PASSAGE - 1
The conversion of an amide to an amine with one carbon atom less by the action of alkaline hydrohalite is known as Hofmann bromamide degradation.
In this reaction, RCONHBr is formed from which the reaction has derived its name. Hofmann reaction is accelerated if the migrating group is more electron-releasing. Hofmann degradation reaction is an intramolecular reaction.
Q. How can the conversion of (i) to (ii) be brought about?
PASSAGE - 1
The conversion of an amide to an amine with one carbon atom less by the action of alkaline hydrohalite is known as Hofmann bromamide degradation.
In this reaction, RCONHBr is formed from which the reaction has derived its name. Hofmann reaction is accelerated if the migrating group is more electron-releasing. Hofmann degradation reaction is an intramolecular reaction.
Q. Which is the rate determining step in Hofmann bromamide degradation?
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PASSAGE - 1
The conversion of an amide to an amine with one carbon atom less by the action of alkaline hydrohalite is known as Hofmann bromamide degradation.
In this reaction, RCONHBr is formed from which the reaction has derived its name. Hofmann reaction is accelerated if the migrating group is more electron-releasing. Hofmann degradation reaction is an intramolecular reaction.
Q. What are the constituent amines formed when the mixture of (i) and (ii) undergoes Hofmann bromamide degradation?
PASSAGE - 2
Treatment of compound O with KMnO4/H+ gave P, which on heating with ammonia gave Q. The compound Q on treatment with Br2/NaOH produced R. On strong heating, Q gave S, which on further treatment with ethyl 2-bromopropanoate in the presence of KOH followed by acidification, gave a compound T.
Q. The compound R is
PASSAGE - 2
Treatment of compound O with KMnO4/H+ gave P, which on heating with ammonia gave Q. The compound Q on treatment with Br2/NaOH produced R. On strong heating, Q gave S, which on further treatment with ethyl 2-bromopropanoate in the presence of KOH followed by acidification, gave a compound T.
Q. The compound T is
Read the following Statement-1(Asseration) and Statement -2 (Reason) and answer as per the options given below :
Q.
Statement - 1: p-Nitrophenol is a stronger acid than o-nitrophenol.
Statement - 2 : Intramolecular hydrogen bonding makes the o-isomer weaker than the p-isomer.
Statement - 1: Benzonitrile is prepared by the reaction of chlorobenzene with potassium cyanide.
Statement - 2 : Cyanide (CN–) is a strong nucleophile.
Statement - 1 : In strongly acidic solutions, aniline becomes more reactive towards electrophilic reagents.
Statement-2 : The amino group being completely protonated in strongly acidic solution, the lone pair of electrons on the nitrogen is no longer available for resonance.
Statement - 1 : Aniline on reaction with NaNO2 / HCl at 0oC followed by coupling with β-naphthol gives a dark blue precipitate. and
Statement - 2 : The colour of the compound formed in the reaction of aniline with NaNO2/HCl at 0oC followed by coupling with β-naphthol is due to the extended conjugation.
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the compounds ‘A’ and ‘B’ respectively are
A compound with molecular mass 180 is acylated with CH3COCl to get a compound with molecular mass 390. The number of amino groups present per molecule of the former compound is :
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The gas leaked from a storage tank of the Union Carbide plant in Bhopal gas tragedy was :
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In the reaction
the product E is :
In the Hofmann bromamide degradation reaction, the number of moles of NaOH and Br2 used per mole of amine produced are :
327 docs|185 tests
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327 docs|185 tests
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