Propanamide on treatment with bromine in an aqueous solution of sodium hydroxide gives:
We can obtain ethylamine by Hoffmann bromamide reaction. The amide used in this reaction is:
Nitro compounds are reduced to amines. The catalyst that is preferred is:
Fe + HCl is preferred due to the following reasons:
- Scrap iron i.e Fe is cheap and commercially easily available
- FeCl2 formed will get hydrolysed and release HCl, so, HCl which is required in the reaction will be produced by itself
- Hence only small amount of HCl is required to initiate the reaction.
Aniline can be prepared by:
is a tertiary amine having IUPAC name as:
Which reaction can be used for the direct conversion of amides into 10 amine ?
What is the end product in the following sequence of reactions ?
Acetamide A B
When Primary amide is treated with an aqueous solution of KOH and bromine, it gives a primary amine. The name of the reaction is:
Hoffmann Bromamide reaction is Treatment of alkylamide with KOH and Bromine gas which converts it into alkylamine with one less carbon atom, this reaction is generally helpful in converting Carboxylic acids to amines with one less carbon atom . For reaction you may refer to internet but i can give you a hint .
Acetamide + KOH + Bromine gas —-> Alkylamine+ KBr + K2CO3 + H20 ( not sure about the products)
Gabriel phthalimide synthesis is used in the preparation of :
To convert methyl cyanide to ethylamine we use:
LiAlH4 reduces all oxiginated functional groups to alcohol and all nitrogenated functional groups to amine thus cyanide is a nitrogenated functional group and to convert cyanide to amine LiAlH4 can be used.