XL Life Science- 2016 GATE Paper (Practice Test) - GATE

R2D2 is a robot. R2D2 can repair aeroplanes. No other robot can repair aeroplanes.
Which of the following can be logically inferred from the above statements?

If |9y−6| =3, then y2 −4y/3 is

Q. 6 – Q. 10 carry two marks each.

Q.

The following graph represents the installed capacity for cement production (in tonnes) and the actual production (in tonnes) of nine cement plants of a cement company. Capacity utilization of a plant is defined as ratio of actual production of cement to installed capacity. A plant with installed capacity of at least 200 tonnes is called a large plant and a plant with lesser capacity is called a small plant. The difference between total production of large plants and small plants, in tonnes is ____.

(Important : you should answer only the numeric value)

A poll of students appearing for masters in engineering indicated that 60 % of the students believed that mechanical engineering is a profession unsuitable for women. A research study on women with masters or higher degrees in mechanical engineering found that 99 % of such women were successful in their professions.
Which of the following can be logically inferred from the above paragraph?

Sourya committee had proposed the establishment of Sourya Institutes of Technology (SITs) in line with Indian Institutes of Technology (IITs) to cater to the technological and industrial needs of a developing country.
Which of the following can be logically inferred from the above sentence?
Based on the proposal,
(i) In the initial years, SIT students will get degrees from IIT.
(ii) SITs will have a distinct national objective.
(iii) SIT like institutions can only be established in consultation with IIT.
(iv) SITs will serve technological needs of a developing country.

Shaquille O’ Neal is a 60% career free throw shooter, meaning that he successfully makes 60 free throws out of 100 attempts on average. What is the probability that he will successfully make exactly 6 free throws in 10 attempts?

The numeral in the units position of 211⁸⁷⁰ + 146¹²⁷ × 3⁴²⁴ is _____.

(Important : you should answer only the numeric value)

Q. 11 – Q. 15 carry one mark each

Q.

The species having shortest B?F bond distance is

The total number of chair conformations possible for 1,2-dimethylcyclohexane is _____.

(Important : you should answer only the numeric value)

‘A harmful substance persists in the environment for a very long period of time’. The
UNACCEPTABLE statement for this fact is

For an enzyme catalyzed reaction, the plot that correctly represents the relationship between the
rate and temperature is

Combinations of a process and equation are given below. The INCORRECT combination is

Q. 16 – Q. 25 carry two marks each.

Q.

The correct comparison of 

Given: The potential energy of two electrons separated by Bohr radius is 27.211 eV. The first Bohr
radius of hydrogen is 0.5292 Å. The electron makes an orbit of radius 0.5295Å around the nucleus
in hydrogen. The calculated ionization energy (eV) of hydrogen atom is __________.

The crystal field stabilization energy (excluding pairing energy, if any) of [CoCl₄]^2? in Δ_o units
is _________.

The correct statement is

Ferrous sulfate on reaction with potassium hexacyanochromate(III) produces a brick red complex.
The number of unpaired electrons on Fe in the red complex is _________.

(Important : you should answer only the numeric value)

The major product formed in the following reaction is (ignore product stereochemistry)

When 1.0 g of urea (Molecular Weight = 60) is dissolved in 200 g of solvent S, the freezing point of S is lowered by 0.25°C. When 1.5 g of a non-electrolyte Y is dissolved in 125 g of S, the freezing point of S is lowered by 0.20°C. The molecular weight of Y is ___________.

The major product formed in the following reaction is

For a weak acid at 298 K the molar conductivities (in ohm^?1 m² mol^?1), at infinite dilution and 0.04 mol dm^?3 are 4.3 × 10^?3 and 1.0 × 10^?3, respectively. The degree of dissociation of the acid (0.04 mol dm^?3) at 298 K is ________.

For propene at 298 K, the molar enthalpy of hydrogenation is -124.27 kJ mol^-1 and the standard
enthalpy of formation is 20.42 kJ mol^-1. For propane at 298 K, the standard enthalpy of formation in kJ mol^-1 is______________.

Q. 26 – Q. 35 carry one mark each.

Q.

Heterologous expression of green fluorescent protein is possible because the genetic code is

Phosphoglucose isomerase was incubated with 0.2 M of glucose 6-phosphate. On reaching
equilibrium, 55% of glucose 6-phosphate was converted to fructose 6-phosphate. The equilibrium constant for this reaction is _______.

Hydrolysis of a peptide involves cleavage of the bond between the atoms

Inter-conversion of UDP-glucose and UDP-galactose is catalyzed by

Gel filtration profile and corresponding activity data for a pure enzyme are shown in the figure
below. The same enzyme sample on SDS-PAGE runs as a 30 kDa polypeptide.

Which one of the following is the correct interpretation of the data?

Amino acid residues predominantly involved in protein-DNA interactions are

Cellulose serves as a structural polymer whereas starch does not. This is because cellulose contains

Molar absorption spectra labeled (i), (ii) and (iii) for three different amino acids are shown below.

Which one of the following is the correct combination of spectral assignments?

The fluidity of a phospholipid membrane increases when the fatty acid

Polypeptides are biosynthesized on the ribosomes inside the cell. Chemical synthesis of polypeptides is also possible through Merrifield’s solid-phase peptide synthesis. In both the cases
the polypeptide chain is extended one amino acid at a time. The direction of polypeptide synthesis is from

Q. 36 – Q. 45 carry two marks each

Q.

Four groups of metabolites are given below. Choose the group in which all the compounds contain
at least one bond whose ΔG'o of hydrolysis is ≤ −7.0kcal/mole.

The ΔG'^o for the malate dehydrogenase catalyzed step of Krebs cycle is +7.1 kcal/mole. Nevertheless, the conversion of malate to oxaloacetate in vivo proceeds spontaneously because the subsequent reaction that consumes oxaloacetate has a ΔG'^o of

When freshly isolated intact mitochondria were incubated with ADP and inorganic phosphate neither the oxygen consumption nor the ATP synthesis could be detected. Addition of succinate resulted in increased oxygen consumption as well as ATP synthesis with time. Subsequent addition of cyanide to this system will result in which one of the following?

Three micrograms of a circular plasmid of 4200 bp was digested with a restriction enzyme and subjected to agarose gel electrophoresis. Five DNA fragments of different sizes were observed and their sizes summed up to 4200 bp. The number of picomoles of DNA ends generated after complete digestion with the enzyme is _______.
(Given: average molecular weight of each base pair is 660 Da)

An enzyme was purified using ion-exchange chromatography and the results are shown in the table below.

Which one of the following is the correct interpretation of these data?

Aspartate residues are found in the active sites of many enzymes. The pK_a for the β-carboxylate of aspartate is 3.86. At physiological pH this group can function as

Kinetic parameters for the enzyme fumarase with three different substrates are given below.

The specificity of fumarase for the substrates decreases in the order

A polypeptide with the amino acid sequence ‘AGKPDHEKAHL’ was dissolved in a buffer of pH 1.8. The predominant form of the polypeptide will have a net charge of

An N-terminal His-tagged protein of molecular weight 40 kDa was purified using Ni-NTA column. This protein sample was subjected to SDS-PAGE. A western blot of the same using anti-His antibodies is shown below.

Which one of the following interpretations is correct?

The sequence of a polypeptide that forms a transmembrane helix is shown below

Which one of the following segments of the peptide is most likely to span the membrane?

Q. 46 – Q. 55 carry one mark each.

Q.

Which of the following is most abundant in the aleurone layer of wheat seeds?

Which of the following does NOT use xylem to transport water?

Which of the following is the closest ancestor of all land plants?

4',6 diamidino 2-phenylindole (DAPI) is a fluorescent dye used to stain the nucleus. Which of the
following plant cells, when mature, cannot be stained by DAPI?

The uptake of nitrogen (N) and phosphorus (P) by plant roots often involves interaction between
root and some symbiotic organisms. Which of the following associations is most commonly found
for the uptake of these two nutrients?

Which of the following summarizes the role of Casparian strip in transport of water in the root?

Atropine is a drug used in the management of pesticide poisoning. Which of the following plants
can serve as a commercial source of this anticholinergic drug?

Which of the following is NOT involved in plant immune response?

Which of the following is a neutral phenomenon?

When a plant is infected by a pathogen at one site, the distal parts of the plant and neighboring
plants develop increased resistance to subsequent pathogen attack. Which of the following
molecules mediates this long-distance signal?

Q. 56 – Q. 65 carry two marks each

Q.

An inbred line of a plant with red flower and tall stem was crossed to another inbred line with white
flower and short stem. The F1 plants, which all had red flower and tall stem, were backcrossed to the line with white flower and short stem, and the following F2 individuals were obtained: 103 red,
tall; 89 white, short; 26 red, short; and 23 white, tall. What is the recombination percentage between
the flower color locus and the stem height locus.

Consider the following pathway controlling time to flowering in wheat:

If batch P of wheat seed is vernalized before sowing and batch Q is not vernalized, then which of
the following statements is most likely to be correct?

The three plots P, Q and R (in different units) in the graph below represent the dependence of
photosynthesis rate (PR), leaf expansion rate (LER) and translocation rate of assimilates (TR) in a
plant on leaf water potential. Which of the following statements is correct in this regard?

PIN proteins are plasma membrane-localized carrier proteins required for polar auxin transport in
plants. Four different carrier proteins are shown in the diagram below labeled P1-P4. Arrow
indicates the direction of auxin flow. Which among these is most likely to be a PIN protein?

An RFLP marker shows sequence polymorphism in two ecotypes (X and Y) of a plant. In ecotype
X, the marker contains one GAATTC site in its sequence, whereas in Y it has the sequence
GAAATC at the same site. The rest of the sequence is identical in both ecotypes. In a genotyping
experiment, the marker was PCR amplified from four different seedlings (P, Q, R, S), completely
digested with EcoRI and the products were analyzed by electrophoresis. The diagram below shows
the band patterns obtained. Based on the information provided, which of the following statements is
correct?

The cell surface expands differently in different plant cells. Two common modes of expansion are
shown below (X and Y). Each rectangular box represents a cell marked with dots on its surface.
The spacing between the dots changes after the cell has undergone expansion as indicated by the
arrow. Which of the following statements is correct with respect to the growth of root hair and
pollen tube?

Hardy Weinberg's equilibrium for a locus with two alleles p and q is mathematically defined as P² +
Q² + 2PQ = 1. Which of the following equations represents the corresponding equilibrium for a
locus with three alleles p, q and r? (P, Q and R represent the frequencies of p, q and r, respectively)

The continuous and dashed lines in the following graph represent the velocity of sap flow in two
different parts of a plant at different times of a day. Which of the following statements is most
appropriate based on this graph?

Given below are the names of some genes/enzymes and their use in genetically modified crops.
Match the two columns.

The basic tenets of the ABC model of Arabidopsis flower development are shown below along with
a diagram.

i. A class genes acting alone determine sepal identity
ii. A and B class genes acting together determine petal identity
iii. B and C class genes acting together determine stamen identity
iv. C class genes acting alone determine carpel identity
v. A and C class genes mutually inhibit each other
Which of the following organ arrangements is found in an A class mutant?

Q. 66 – Q. 75 carry one mark each.

Q.

Which one of the following is the most appropriate technique to determine the relatedness of two bacterial species?

Which one of the following phages undergoes non-integrative lysogenic phase?

Which one of the following is NOT a part of human microbiome?

Resident macrophages of _________ are called Kupffer cells

The enzyme responsible for generation of hypochlorous ions during phagocytosis is

Teichoic acid is composed of repetitive units of

Biofilm produced by bacteria is detected by

The precursor for the synthesis of aromatic amino acids is

The net yield of NADH in the Embden-Meyerhof pathway in E. coli is________.

(Important : you should answer only the numeric value)

E. coli ribonuclease contains 124 amino acids. The number of nucleotides present in the gene encoding the protein is _______________.

(Important : you should answer only the numeric value)

Q. 11 – Q. 20 carry two marks each.

Q.

Which of the following infectious agents cross the blood-brain barrier?

(P) Streptococcus pneumoniae

(Q) Coxsackie virus
(R) Rotavirus

(S) Streptococcus pyogenes

At OD540_nm= 0.5, which one of the following bacterial mono-dispersed cell suspensions will have (i)
maximum and (ii) minimum number of cells?

(P) Mycoplasma pneumoniae (Q) Micrococcus luteus
(R) Bacillus subtilis (S) Escherichia coli

Which one of the following enzyme combinations allows some bacteria to utilize acetate through glyoxylate pathway?
(P) Isocitrate lyase                                   (Q) Isocitrate dehydrogenase
(R) Succinyl CoA synthetase                    (S) Malate synthase

The decimal reduction time (D₁₂₁) for Clostridium botulinum spores is 0.2 min. The time required to reduce the spore count from 10¹² to one spore at 121°C is_______ minutes

(Important : you should answer only the numeric value)

E. coli requires three genes, galK (kinase), galT (transacetylase) and galE (epimerase) to utilize galactose. If there is a mutation in any one of these genes, the mutant cannot utilize galactose. Which one of the following combinations of merodiploids will support the growth of mutants on galactose?

Nitrogenase reduces N2 to NH3. Metal co-factors required for this activity are __________.

If a bacterial cell contains 5,000 genes and if the average mutation frequency per gene is 2 ×10^-4 per generation, the average number of new mutations per generation is _________.

(Important : you should answer only the numeric value)

The growth profile of E. coli on glucose plus lactose is shown below. The specific growth rate of the second exponential phase is____h^-1.

Match the cell structure components given in Group I with appropriate functions from Group II.

Match the antibiotics given in Group I with appropriate targets from Group II.

Q. 86 – Q. 95 carry one mark each.

Q.

Acorn worms (Saccoglassus sp.) belong to which ONE of the following Phyla?

A population of Bees develops resistance to pesticides and the trait gets fixed within a few
generations. This is an example of

The nature of the polymorphic DNA fragment used for mapping is

The sex of a Drosophila melanogaster, which has 4 copies of X-chromosomes and 4 sets of autosomes will be

Which of the following cations are found in higher concentration in extracellular fluid as compared
to intracellular fluid in animals?

Detoxification of alcohol occurs in liver cells where peroxisomal enzymes remove hydrogen from it, which is

When cells are treated with cyanide, which ONE of the following organelles will have the highest
level of cyanide inside?

Toxoplasmosis in humans is caused by Toxoplasma gondii, an obligate intracellular parasite with two different life cycles, sexual and asexual. The sexual cycle occurs in which ONE of the following definitive hosts?

Which ONE of the following is often a life-threatening systemic inflammatory response?

During the gastrulation stage of amphibian development, ectoderm formation takes place by the
expansion of epithelial cell sheet over mesodermal cells. This type of cell movement is termed as

Q. 96 – Q. 105 carry two marks each.

Q.

In a population, 600 individuals have MM blood group, 300 have MN blood group and 100 have
NN blood group. What will be the frequencies of M and N alleles in this population?

The molecules, hexanoic acid, lysine, histidine and glucose, each contain 6 carbon atoms, but have
completely different properties due to the presence of different functional groups. Which ONE of these molecules has a high calorific value?

The primary function of polysaccharides attached to glycoproteins in the animal cell membrane is
to

Which ONE of the following mechanisms is used to coordinate the expression of multiple, related
genes in eukaryotic cells?

In an experiment involving development of 64-cell stage sea urchin, an isolated animal hemisphere was combined with isolated micromeres. Which ONE of the following will be the resulting
structure?

Glycoprotein hormones, hCG and eCG, are synthesized in women and mares respectively, during pregnancy. Both of these chorionic gonadotropin hormones

Entamoeba histolytica is an intestinal parasite that causes dysentery in humans. This parasite
resides in the isotonic environment of intestine and other tissues in the human body and does not
possess contractile vacuoles. If this parasite is placed in fresh water, it will

In an experiment involving Drosophila development, a large amount of purified bicoid mRNA was injected into the posterior end of a wild-type embryo, the resulting developing embryo will have

The migratory desert locust, Schistocerca gregaria, exists in two mutually exclusive forms: a
short-winged, uniformly colored, solitary insect and a long-winged, brightly colored, gregarious morph. These phenotypes depend on crowding. Such phenotypic plasticity is called

Given below is the list of animals and their respective characteristics.

Which ONE of the following represents the correct match?

Q. 106 – Q. 115 carry one mark each.

Q.

Bread staling is caused by _________.

The grades of tea in the increasing order of their leaf size are ____, _____ and _____

Fruit juice is being pasteurized in a tubular heat exchanger. The retention time in holding tube of
0.2 m² cross sectional area is 3 seconds. If the flow rate of juice is 0.4 m3 s-1, the length of the
holding tube in m, is _____

The oil, which experiences flavor reversion even at the lower peroxide value is _______.

80 kg of wheat containing 10 kg of moisture has been dried to a moisture content of 8% wet basis in 3 hours under constant rate period of drying. The drying rate in kg h^-1 is _____

The rate of cream separation in a disc bowl centrifuge can be increased by ______

Rigor mortis is caused due to __________

Oxygen is permeating through an EVOH film of thickness ‘t’ and solubility coefficient ‘S’. If
diffusivity of oxygen through the film is ‘D’, then permeability of oxygen through the film will be ___________

Condensing steam is used to heat vegetable oil in a double pipe co-current heat exchanger. If the
inlet and outlet temperature of steam are T_hi and T_ho, and for vegetable oil T_ci and T_co respectively, the log mean temperature difference (ΔT_LM ) will be _______

To produce Blue veined cheese, the curd is inoculated with strains of ________.

Q. 116 – Q. 125 carry two marks each

Q.

Match the food spoilage organisms given in Column I with the associated foods given in Column II

Fluid is flowing inside a pipe of radius ‘R’ in fully developed laminar flow. If the velocity of the
fluid at the centre at a distance ‘L’ is ‘v_max ’, velocity at radial distance of ¾ (R) will be __times v_max

The amount of sugar to be added (kg) to 40 kg of mango pulp to increase its total soluble solids
from 20% wt. to 65% wt. is ________

a) Assertion: Acidulates are added in soft drinks to provide a buffering action.

r) Reason: Buffers tend to prevent changes in pH and prevent excessive tartness.

Choose the correct answer from the following

The D₁₂₁ and Z values for C. botulinum spores in canned food are 0.2 min and 10^oC, respectively. Total time required in min, to reduce the spores from 10² to 10^-6 at 111^oC is _______

In a typical Psychrometric Chart shown below, the processes OP, OQ and OR related to air water vapor mixture are _____, _______ and __________.

Match the enzymes in Column I with their functions in Column II

Match the terms in Column I with their most appropriate description in Column II

Match the products in Column I with their Original Phase in Column II

a) Assertion: Presence of low sulphur containing amino acids makes casein in milk to boil, sterilize
and concentrate without coagulation even at higher temperatures.
r) Reason: This is due to the restricted formation of di-sulphide bonds resulting in increased
stability. Choose the correct answer from the following