What is the primary neurotransmitter involved in the brain's reward pathway related to substance use disorders?

Dopamine

True or False: Psychological dependence is characterized by physical symptoms when substance use is reduced.

False. Psychological dependence is characterized by persistent cravings for the substance.

The ICD-10 criteria for substance dependence require the presence of how many symptoms within the past year?

Three or more symptoms

Riddle: I can bring euphoria and relaxation but can lead to dependence and withdrawal. What am I?

Alcohol

Fill-in-the-blank: The __________ refers to the phenomenon where the effects of alcohol are more pronounced when BAC is increasing.

Mellanby effect

Which organ metabolizes about 90% of absorbed alcohol?

Liver

What is the most common sign of alcohol withdrawal occurring after 6-8 hours?

Tremors

True or False: Korsakoff's syndrome is characterized by primarily retrograde amnesia.

False. Korsakoff's syndrome is characterized by anterograde amnesia being more pronounced than retrograde amnesia.

Which screening tool consists of four questions to assess alcohol use disorder?

CAGE questionnaire

Fill-in-the-blank: The treatment of Wernicke's encephalopathy involves administering high doses of __________.

Thiamine

What is the primary active ingredient in cannabis responsible for its psychoactive effects?

Tetrahydrocannabinol (THC)

Riddle: I am known for causing hallucinations and can lead to a 'bad trip.' What am I?

Hallucinogens

True or False: Opioid withdrawal symptoms typically begin within 24 hours after the last dose.

False. Opioid withdrawal symptoms typically begin around 6-8 hours after the last dose.

Which condition is characterized by a lack of motivation and interest in activities due to cannabis use?

Amotivational syndrome

Fill-in-the-blank: The symptoms of opioid withdrawal resemble a __________ condition.

Flu-like

What is the main addictive component found in tobacco?

Nicotine

Which drug is known for causing respiratory depression and can be fatal in overdose?

Opioids

Riddle: I am a plant-derived stimulant that can lead to dependency and increased heart rate. What am I?

Caffeine

Fill-in-the-blank: The condition where chronic alcohol use leads to visual hallucinations and confusion is known as __________.

Delirium tremens

What is the legal limit for blood alcohol concentration (BAC) for driving in India?

30 mg/dL

True or False: Cocaine primarily functions by enhancing the reuptake of dopamine.

False. Cocaine primarily functions by blocking dopamine reuptake.

What term describes a pattern of substance use that causes harm but does not meet the criteria for dependence?

Harmful use

Fill-in-the-blank: The treatment approach that replaces illegal short-acting opioids with safer long-acting opioids is called __________.

Opioid substitution therapy

What is the common withdrawal symptom associated with nicotine cessation?

Craving for nicotine

Riddle: I can make you feel excited initially but can lead to severe anxiety if overused. What am I?

Caffeine

True or False: Benzodiazepines can cause withdrawal symptoms similar to those of alcohol.

True

What is the primary treatment for opioid overdose?

Intravenous naloxone

Fill-in-the-blank: The __________ syndrome is associated with a deficiency in thiamine due to chronic alcohol use.

Korsakoff's

What is the term for the psychological phenomenon where past cannabis effects resurface without current use?

Flashback phenomenon

Riddle: I am a synthetic opioid, often used in detox, that helps alleviate withdrawal symptoms. What am I?

Methadone