IIT JAM Biotechnology Past Year Papers - 2019 | IIT JAM Biotechnology Past Year Papers - Biotechnology Engineering (BT) PDF Download

 Page 1


IIT JAM BIOTECHNOLOGY 2019  
             
 
 
SECTION – A 
MULTIPLE CHOICE QUESTIONS (MCQ) 
Q. 1 – Q.10 carry one mark each. 
 
Q.1 The glycosidic linkages in cellulose and amylose 
are ________, respectively.  
(A) a 1-4 and ß 1-4  
(B) ß 1-4 and a 1-4  
(C) ß 1-4 and a 1-6  
(D) a 1-4 and a 1-2  
 
Q.2 A mutation in the operator locus of lac operon 
that confers constitutive expression of ß-
galactosidase is ________.  
(A) cis dominant  
(B) trans dominant  
(C) co-dominant  
(D) dominant negative 
 
Q.3 Which one of the points ?? = (
?? ?? ,
?? ?? ),?? =
(
?? ?? ,
?? ?? ),?? = (
?? ?? ,
????
?? )?????? ?? = (
????
?? ,
?? ?? ) lies ABOVE 
the parabola ?? = ????
?? and INSIDE the circle ?? ?? +
?? ?? = ??? 
(A) P  
(B) Q  
(C) R  
(D) S 
 
Q.4 Let ?? = {??,??,??,??,?? }  A subset S is chosen 
uniformly at random from the non-empty 
subsets of U. What is the probability that S does 
NOT have two consecutive elements? 
(A) 9/31  
(B) 10/31 
(C) 11/31  
(D) 12/31  
 
Q.5 Which one of the following figures represents 
the correct sequence of phases in adult 
eukaryotic cell cycle? 
 
 
 
 
 
 
 
Q.6 At what pH does poly-Glu in an aqueous solution 
form a-helical structure?  
(A) 3  
(B) 7  
(C) 9  
(D) 12  
 
Q.7 The dimensions of coefficient of viscosity are 
_______.  
(A) ML
-1
T
-1
  
(B) ML
-1
T
-2
  
(C) ML
-2
T
-2
  
(D) ML
-2
T
-1
  
 
Q.8 Match the entries in Group I with the entries in 
Group II  
Group I   Group II  
(P) Nylon    (i) Isoprene  
(Q) Natural rubber   (ii) Hexose  
(R) Starch    (iii) Amino acid  
(S) Myoglobin   (iv) Adipic acid  
(A) P-iv, Q-i, R-ii, S-iii  
(B) P-iv, Q-i, R-iii, S-ii  
(C) P-iv, Q-iii, R-ii, S-i  
(D) P-ii, Q-iv, R-i, S-iii  
 
Q.9 The technique that involves impacting samples 
with electrons is _______.  
(A) NMR spectroscopy  
(B) ESI mass spectrometry  
(C) IR spectroscopy  
(D) UV-vis spectroscopy  
 
Q.10 The orbital angular momentum of hydrogen 
atom in the ground state is ________.  
(A) 0  
(B) 
h
2??  
(C) 
h
2
  
(D) h  
 
  
Page 2


IIT JAM BIOTECHNOLOGY 2019  
             
 
 
SECTION – A 
MULTIPLE CHOICE QUESTIONS (MCQ) 
Q. 1 – Q.10 carry one mark each. 
 
Q.1 The glycosidic linkages in cellulose and amylose 
are ________, respectively.  
(A) a 1-4 and ß 1-4  
(B) ß 1-4 and a 1-4  
(C) ß 1-4 and a 1-6  
(D) a 1-4 and a 1-2  
 
Q.2 A mutation in the operator locus of lac operon 
that confers constitutive expression of ß-
galactosidase is ________.  
(A) cis dominant  
(B) trans dominant  
(C) co-dominant  
(D) dominant negative 
 
Q.3 Which one of the points ?? = (
?? ?? ,
?? ?? ),?? =
(
?? ?? ,
?? ?? ),?? = (
?? ?? ,
????
?? )?????? ?? = (
????
?? ,
?? ?? ) lies ABOVE 
the parabola ?? = ????
?? and INSIDE the circle ?? ?? +
?? ?? = ??? 
(A) P  
(B) Q  
(C) R  
(D) S 
 
Q.4 Let ?? = {??,??,??,??,?? }  A subset S is chosen 
uniformly at random from the non-empty 
subsets of U. What is the probability that S does 
NOT have two consecutive elements? 
(A) 9/31  
(B) 10/31 
(C) 11/31  
(D) 12/31  
 
Q.5 Which one of the following figures represents 
the correct sequence of phases in adult 
eukaryotic cell cycle? 
 
 
 
 
 
 
 
Q.6 At what pH does poly-Glu in an aqueous solution 
form a-helical structure?  
(A) 3  
(B) 7  
(C) 9  
(D) 12  
 
Q.7 The dimensions of coefficient of viscosity are 
_______.  
(A) ML
-1
T
-1
  
(B) ML
-1
T
-2
  
(C) ML
-2
T
-2
  
(D) ML
-2
T
-1
  
 
Q.8 Match the entries in Group I with the entries in 
Group II  
Group I   Group II  
(P) Nylon    (i) Isoprene  
(Q) Natural rubber   (ii) Hexose  
(R) Starch    (iii) Amino acid  
(S) Myoglobin   (iv) Adipic acid  
(A) P-iv, Q-i, R-ii, S-iii  
(B) P-iv, Q-i, R-iii, S-ii  
(C) P-iv, Q-iii, R-ii, S-i  
(D) P-ii, Q-iv, R-i, S-iii  
 
Q.9 The technique that involves impacting samples 
with electrons is _______.  
(A) NMR spectroscopy  
(B) ESI mass spectrometry  
(C) IR spectroscopy  
(D) UV-vis spectroscopy  
 
Q.10 The orbital angular momentum of hydrogen 
atom in the ground state is ________.  
(A) 0  
(B) 
h
2??  
(C) 
h
2
  
(D) h  
 
  
IIT JAM BIOTECHNOLOGY 2019  
             
 
Q. 11 – Q. 30 carry two marks each. 
 
Q.11 Let ?? =
v?? +?? ?? ???????? =
v?? -?? ?? . Then 
?????? ???8
?? ?? +?? ?? ?? ?? -?? ?? 
(A) is 1  
(B) is ½  
(C) is 0  
(D) does not exist  
 
Q.12 In how many ways can one write the elements 
1, 2, 3, 4 in a sequence ?? ?? ,?? ?? ,?? ?? ,?? ??  with?? ?? ?
?????  
(A) 9  
(B) 10  
(C) 11  
(D) 12 
 
Q.13 Simplify 
???????? ??+???????? +
??+???????? ????????  
(A) 2 sec A  
(B) 2 cosec A   
(C) sec A  
(D) cosec A  
 
Q.14 The evolution of eyes in octopus and in human 
is an example of ________.  
(A) divergent evolution  
(B) convergent evolution  
(C) adaptive radiation  
(D) genetic drift  
 
Q.15 Which one of the following modifications 
occurs both on DNA and protein?  
(A) ADP-ribosylation  
(B) Methylation  
(C) Sumoylation  
(D) Ubiquitination  
 
Q.16 Solutions of the following peptides are 
prepared separately at a concentration of 1 
mM. Among these four, which one has the 
highest A280?  
(A) Ser-Val-Trp-Asp-Phe-Gly-Tyr-Trp-Ala  
(B) Gln-Leu-Glu-Phe-Thr-Leu-Asp-Gly-Tyr  
(C) Met-Gly-Val-Ileu-Asp-Ser-Ala-Trp-His  
(D) His-Pro-Gly-Asp-Val-Ileu-Phe-Met-Leu  
 
Q.17 The free energy required to synthesize a mixed 
anhydride bond of 1,3-bisphosphoglycerate is 
generated by the oxidation of ________.  
(A) an aldehyde to acid  
(B) an alcohol to acid  
(C) an alcohol to aldehyde  
(D) NADH to NAD+  
 
 
Q.18 The following reaction is an example of 
___________.  
  
(A) enolization  
(B) racemization  
(C) isomerization  
(D) epimerization  
 
Q.19 Which one of the following parameters changes 
upon doubling the enzyme concentration?  
(A) K M  
(B) V max  
(C) k cat  
(D) K eq  
 
Q.20 Which one of the following statements is a 
correct description of modes of action of taxol 
and colchicine?  
(A) Taxol causes DNA damage and colchicine 
prevents microtubule formation  
(B) Taxol stabilizes microtubules and colchicine 
inhibits protein synthesis  
(C) Taxol destabilizes microtubules and 
colchicine promotes microtubule formation  
(D) Taxol stabilizes microtubules and colchicine 
prevents microtubule formation  
 
Q.21 In a simple microscope, _______.  
(A) a lens with negative power is used  
(B) the focal length of the lens is less than the 
least distance for clear vision  
(C) the focal length of the lens is greater than 
the least distance for clear vision  
(D) magnification depends only on the focal 
length of the lens 
  
Q.22 Which one of the following statements is 
INCORRECT with respect to bacterial 
conjugation?  
(A) It facilitates transfer of genetic material  
(B) It requires flagellum  
(C) It can spread antibiotic resistance  
(D) It can transfer virulence factors  
 
  
Page 3


IIT JAM BIOTECHNOLOGY 2019  
             
 
 
SECTION – A 
MULTIPLE CHOICE QUESTIONS (MCQ) 
Q. 1 – Q.10 carry one mark each. 
 
Q.1 The glycosidic linkages in cellulose and amylose 
are ________, respectively.  
(A) a 1-4 and ß 1-4  
(B) ß 1-4 and a 1-4  
(C) ß 1-4 and a 1-6  
(D) a 1-4 and a 1-2  
 
Q.2 A mutation in the operator locus of lac operon 
that confers constitutive expression of ß-
galactosidase is ________.  
(A) cis dominant  
(B) trans dominant  
(C) co-dominant  
(D) dominant negative 
 
Q.3 Which one of the points ?? = (
?? ?? ,
?? ?? ),?? =
(
?? ?? ,
?? ?? ),?? = (
?? ?? ,
????
?? )?????? ?? = (
????
?? ,
?? ?? ) lies ABOVE 
the parabola ?? = ????
?? and INSIDE the circle ?? ?? +
?? ?? = ??? 
(A) P  
(B) Q  
(C) R  
(D) S 
 
Q.4 Let ?? = {??,??,??,??,?? }  A subset S is chosen 
uniformly at random from the non-empty 
subsets of U. What is the probability that S does 
NOT have two consecutive elements? 
(A) 9/31  
(B) 10/31 
(C) 11/31  
(D) 12/31  
 
Q.5 Which one of the following figures represents 
the correct sequence of phases in adult 
eukaryotic cell cycle? 
 
 
 
 
 
 
 
Q.6 At what pH does poly-Glu in an aqueous solution 
form a-helical structure?  
(A) 3  
(B) 7  
(C) 9  
(D) 12  
 
Q.7 The dimensions of coefficient of viscosity are 
_______.  
(A) ML
-1
T
-1
  
(B) ML
-1
T
-2
  
(C) ML
-2
T
-2
  
(D) ML
-2
T
-1
  
 
Q.8 Match the entries in Group I with the entries in 
Group II  
Group I   Group II  
(P) Nylon    (i) Isoprene  
(Q) Natural rubber   (ii) Hexose  
(R) Starch    (iii) Amino acid  
(S) Myoglobin   (iv) Adipic acid  
(A) P-iv, Q-i, R-ii, S-iii  
(B) P-iv, Q-i, R-iii, S-ii  
(C) P-iv, Q-iii, R-ii, S-i  
(D) P-ii, Q-iv, R-i, S-iii  
 
Q.9 The technique that involves impacting samples 
with electrons is _______.  
(A) NMR spectroscopy  
(B) ESI mass spectrometry  
(C) IR spectroscopy  
(D) UV-vis spectroscopy  
 
Q.10 The orbital angular momentum of hydrogen 
atom in the ground state is ________.  
(A) 0  
(B) 
h
2??  
(C) 
h
2
  
(D) h  
 
  
IIT JAM BIOTECHNOLOGY 2019  
             
 
Q. 11 – Q. 30 carry two marks each. 
 
Q.11 Let ?? =
v?? +?? ?? ???????? =
v?? -?? ?? . Then 
?????? ???8
?? ?? +?? ?? ?? ?? -?? ?? 
(A) is 1  
(B) is ½  
(C) is 0  
(D) does not exist  
 
Q.12 In how many ways can one write the elements 
1, 2, 3, 4 in a sequence ?? ?? ,?? ?? ,?? ?? ,?? ??  with?? ?? ?
?????  
(A) 9  
(B) 10  
(C) 11  
(D) 12 
 
Q.13 Simplify 
???????? ??+???????? +
??+???????? ????????  
(A) 2 sec A  
(B) 2 cosec A   
(C) sec A  
(D) cosec A  
 
Q.14 The evolution of eyes in octopus and in human 
is an example of ________.  
(A) divergent evolution  
(B) convergent evolution  
(C) adaptive radiation  
(D) genetic drift  
 
Q.15 Which one of the following modifications 
occurs both on DNA and protein?  
(A) ADP-ribosylation  
(B) Methylation  
(C) Sumoylation  
(D) Ubiquitination  
 
Q.16 Solutions of the following peptides are 
prepared separately at a concentration of 1 
mM. Among these four, which one has the 
highest A280?  
(A) Ser-Val-Trp-Asp-Phe-Gly-Tyr-Trp-Ala  
(B) Gln-Leu-Glu-Phe-Thr-Leu-Asp-Gly-Tyr  
(C) Met-Gly-Val-Ileu-Asp-Ser-Ala-Trp-His  
(D) His-Pro-Gly-Asp-Val-Ileu-Phe-Met-Leu  
 
Q.17 The free energy required to synthesize a mixed 
anhydride bond of 1,3-bisphosphoglycerate is 
generated by the oxidation of ________.  
(A) an aldehyde to acid  
(B) an alcohol to acid  
(C) an alcohol to aldehyde  
(D) NADH to NAD+  
 
 
Q.18 The following reaction is an example of 
___________.  
  
(A) enolization  
(B) racemization  
(C) isomerization  
(D) epimerization  
 
Q.19 Which one of the following parameters changes 
upon doubling the enzyme concentration?  
(A) K M  
(B) V max  
(C) k cat  
(D) K eq  
 
Q.20 Which one of the following statements is a 
correct description of modes of action of taxol 
and colchicine?  
(A) Taxol causes DNA damage and colchicine 
prevents microtubule formation  
(B) Taxol stabilizes microtubules and colchicine 
inhibits protein synthesis  
(C) Taxol destabilizes microtubules and 
colchicine promotes microtubule formation  
(D) Taxol stabilizes microtubules and colchicine 
prevents microtubule formation  
 
Q.21 In a simple microscope, _______.  
(A) a lens with negative power is used  
(B) the focal length of the lens is less than the 
least distance for clear vision  
(C) the focal length of the lens is greater than 
the least distance for clear vision  
(D) magnification depends only on the focal 
length of the lens 
  
Q.22 Which one of the following statements is 
INCORRECT with respect to bacterial 
conjugation?  
(A) It facilitates transfer of genetic material  
(B) It requires flagellum  
(C) It can spread antibiotic resistance  
(D) It can transfer virulence factors  
 
  
IIT JAM BIOTECHNOLOGY 2019  
             
 
 
Q.23 A particle starting from rest is subjected to a 
constant force. The plot of distance traveled 
along the direction of the force as a function of 
time is a/an ______.  
(A) straight line  
(B) circle  
(C) parabola  
(D) ellipse  
 
Q.24 Indole acetic acid (IAA) is involved in ______.  
(A) gravitropism  
(B) flowering  
(C) ripening  
(D) senescence  
 
Q.25 Which one of the following remains unchanged 
when light waves enter water from air?  
(A) Wavelength  
(B) Wavenumber  
(C) Frequency  
(D) Intensity  
 
Q.26 According to the kinetic theory of gases, the 
average energy of a diatomic molecule in an 
ideal gas depends on _______.  
(A) mass of each atom and the temperature  
(B) mass of each atom and the bond length  
(C) mass of each atom, bond length, and 
temperature  
(D) temperature only  
 
Q.27 Match the entries in Group I with entries in 
Group II  
Group I    Group II  
(P) Bacteria   (i) Malaria  
(Q) Virus    (ii) Tuberculosis  
(R) Protozoa   (iii) Influenza  
(S) Autoantibodies  (iv) Myasthenia gravis 
(A) P-ii, Q-i, R-iii, S-iv  
(B) P-ii, Q-iii, R-i, S-iv  
(C) P-iv, Q-iii, R-i, S-ii  
(D) P-i, Q-iv, R-ii, S-iii  
 
Q.28 pKa increases in the order _______.  
(A) HN 3 > NH 3OH
+
 > N 2H 5
+
 > NH 3  
(B) NH 3OH
+
 > N 2H 5
+
 > HN 3 > NH 3  
(C) NH 3 > NH 3OH+ > N 2H 5
+
 > HN 3  
(D) HN 3 > N 2H 5
+
 > NH 3 > NH 3OH
+
  
 
 
 
 
 
Q.29 H 2 reacts with trans-(Ph 3P) 2Ir(CO)Cl to primarily 
produce _______.  
  
 
 
Q.30 Among the following species, the metal center 
that has the highest number of unpaired 
electrons is _______.  
(A) VCl 4  
(B) Ni(CO) 4  
(C) [AuCl 4]
 ?
  
(D) [CdBr 4]
 2 ?
  
Page 4


IIT JAM BIOTECHNOLOGY 2019  
             
 
 
SECTION – A 
MULTIPLE CHOICE QUESTIONS (MCQ) 
Q. 1 – Q.10 carry one mark each. 
 
Q.1 The glycosidic linkages in cellulose and amylose 
are ________, respectively.  
(A) a 1-4 and ß 1-4  
(B) ß 1-4 and a 1-4  
(C) ß 1-4 and a 1-6  
(D) a 1-4 and a 1-2  
 
Q.2 A mutation in the operator locus of lac operon 
that confers constitutive expression of ß-
galactosidase is ________.  
(A) cis dominant  
(B) trans dominant  
(C) co-dominant  
(D) dominant negative 
 
Q.3 Which one of the points ?? = (
?? ?? ,
?? ?? ),?? =
(
?? ?? ,
?? ?? ),?? = (
?? ?? ,
????
?? )?????? ?? = (
????
?? ,
?? ?? ) lies ABOVE 
the parabola ?? = ????
?? and INSIDE the circle ?? ?? +
?? ?? = ??? 
(A) P  
(B) Q  
(C) R  
(D) S 
 
Q.4 Let ?? = {??,??,??,??,?? }  A subset S is chosen 
uniformly at random from the non-empty 
subsets of U. What is the probability that S does 
NOT have two consecutive elements? 
(A) 9/31  
(B) 10/31 
(C) 11/31  
(D) 12/31  
 
Q.5 Which one of the following figures represents 
the correct sequence of phases in adult 
eukaryotic cell cycle? 
 
 
 
 
 
 
 
Q.6 At what pH does poly-Glu in an aqueous solution 
form a-helical structure?  
(A) 3  
(B) 7  
(C) 9  
(D) 12  
 
Q.7 The dimensions of coefficient of viscosity are 
_______.  
(A) ML
-1
T
-1
  
(B) ML
-1
T
-2
  
(C) ML
-2
T
-2
  
(D) ML
-2
T
-1
  
 
Q.8 Match the entries in Group I with the entries in 
Group II  
Group I   Group II  
(P) Nylon    (i) Isoprene  
(Q) Natural rubber   (ii) Hexose  
(R) Starch    (iii) Amino acid  
(S) Myoglobin   (iv) Adipic acid  
(A) P-iv, Q-i, R-ii, S-iii  
(B) P-iv, Q-i, R-iii, S-ii  
(C) P-iv, Q-iii, R-ii, S-i  
(D) P-ii, Q-iv, R-i, S-iii  
 
Q.9 The technique that involves impacting samples 
with electrons is _______.  
(A) NMR spectroscopy  
(B) ESI mass spectrometry  
(C) IR spectroscopy  
(D) UV-vis spectroscopy  
 
Q.10 The orbital angular momentum of hydrogen 
atom in the ground state is ________.  
(A) 0  
(B) 
h
2??  
(C) 
h
2
  
(D) h  
 
  
IIT JAM BIOTECHNOLOGY 2019  
             
 
Q. 11 – Q. 30 carry two marks each. 
 
Q.11 Let ?? =
v?? +?? ?? ???????? =
v?? -?? ?? . Then 
?????? ???8
?? ?? +?? ?? ?? ?? -?? ?? 
(A) is 1  
(B) is ½  
(C) is 0  
(D) does not exist  
 
Q.12 In how many ways can one write the elements 
1, 2, 3, 4 in a sequence ?? ?? ,?? ?? ,?? ?? ,?? ??  with?? ?? ?
?????  
(A) 9  
(B) 10  
(C) 11  
(D) 12 
 
Q.13 Simplify 
???????? ??+???????? +
??+???????? ????????  
(A) 2 sec A  
(B) 2 cosec A   
(C) sec A  
(D) cosec A  
 
Q.14 The evolution of eyes in octopus and in human 
is an example of ________.  
(A) divergent evolution  
(B) convergent evolution  
(C) adaptive radiation  
(D) genetic drift  
 
Q.15 Which one of the following modifications 
occurs both on DNA and protein?  
(A) ADP-ribosylation  
(B) Methylation  
(C) Sumoylation  
(D) Ubiquitination  
 
Q.16 Solutions of the following peptides are 
prepared separately at a concentration of 1 
mM. Among these four, which one has the 
highest A280?  
(A) Ser-Val-Trp-Asp-Phe-Gly-Tyr-Trp-Ala  
(B) Gln-Leu-Glu-Phe-Thr-Leu-Asp-Gly-Tyr  
(C) Met-Gly-Val-Ileu-Asp-Ser-Ala-Trp-His  
(D) His-Pro-Gly-Asp-Val-Ileu-Phe-Met-Leu  
 
Q.17 The free energy required to synthesize a mixed 
anhydride bond of 1,3-bisphosphoglycerate is 
generated by the oxidation of ________.  
(A) an aldehyde to acid  
(B) an alcohol to acid  
(C) an alcohol to aldehyde  
(D) NADH to NAD+  
 
 
Q.18 The following reaction is an example of 
___________.  
  
(A) enolization  
(B) racemization  
(C) isomerization  
(D) epimerization  
 
Q.19 Which one of the following parameters changes 
upon doubling the enzyme concentration?  
(A) K M  
(B) V max  
(C) k cat  
(D) K eq  
 
Q.20 Which one of the following statements is a 
correct description of modes of action of taxol 
and colchicine?  
(A) Taxol causes DNA damage and colchicine 
prevents microtubule formation  
(B) Taxol stabilizes microtubules and colchicine 
inhibits protein synthesis  
(C) Taxol destabilizes microtubules and 
colchicine promotes microtubule formation  
(D) Taxol stabilizes microtubules and colchicine 
prevents microtubule formation  
 
Q.21 In a simple microscope, _______.  
(A) a lens with negative power is used  
(B) the focal length of the lens is less than the 
least distance for clear vision  
(C) the focal length of the lens is greater than 
the least distance for clear vision  
(D) magnification depends only on the focal 
length of the lens 
  
Q.22 Which one of the following statements is 
INCORRECT with respect to bacterial 
conjugation?  
(A) It facilitates transfer of genetic material  
(B) It requires flagellum  
(C) It can spread antibiotic resistance  
(D) It can transfer virulence factors  
 
  
IIT JAM BIOTECHNOLOGY 2019  
             
 
 
Q.23 A particle starting from rest is subjected to a 
constant force. The plot of distance traveled 
along the direction of the force as a function of 
time is a/an ______.  
(A) straight line  
(B) circle  
(C) parabola  
(D) ellipse  
 
Q.24 Indole acetic acid (IAA) is involved in ______.  
(A) gravitropism  
(B) flowering  
(C) ripening  
(D) senescence  
 
Q.25 Which one of the following remains unchanged 
when light waves enter water from air?  
(A) Wavelength  
(B) Wavenumber  
(C) Frequency  
(D) Intensity  
 
Q.26 According to the kinetic theory of gases, the 
average energy of a diatomic molecule in an 
ideal gas depends on _______.  
(A) mass of each atom and the temperature  
(B) mass of each atom and the bond length  
(C) mass of each atom, bond length, and 
temperature  
(D) temperature only  
 
Q.27 Match the entries in Group I with entries in 
Group II  
Group I    Group II  
(P) Bacteria   (i) Malaria  
(Q) Virus    (ii) Tuberculosis  
(R) Protozoa   (iii) Influenza  
(S) Autoantibodies  (iv) Myasthenia gravis 
(A) P-ii, Q-i, R-iii, S-iv  
(B) P-ii, Q-iii, R-i, S-iv  
(C) P-iv, Q-iii, R-i, S-ii  
(D) P-i, Q-iv, R-ii, S-iii  
 
Q.28 pKa increases in the order _______.  
(A) HN 3 > NH 3OH
+
 > N 2H 5
+
 > NH 3  
(B) NH 3OH
+
 > N 2H 5
+
 > HN 3 > NH 3  
(C) NH 3 > NH 3OH+ > N 2H 5
+
 > HN 3  
(D) HN 3 > N 2H 5
+
 > NH 3 > NH 3OH
+
  
 
 
 
 
 
Q.29 H 2 reacts with trans-(Ph 3P) 2Ir(CO)Cl to primarily 
produce _______.  
  
 
 
Q.30 Among the following species, the metal center 
that has the highest number of unpaired 
electrons is _______.  
(A) VCl 4  
(B) Ni(CO) 4  
(C) [AuCl 4]
 ?
  
(D) [CdBr 4]
 2 ?
  
IIT JAM BIOTECHNOLOGY 2019  
             
 
  
 
SECTION -B  
MULTIPLE SELECT QUESTIONS (MSQ) 
 
Q. 31 – Q. 40 carry two marks each.  
 
Q.31 Pick the correct statement(s) with respect to 
the inter-conversion of the topoisomers of a 
circularly closed double stranded DNA.  
(A) Only one strand needs to be cut  
(B) Both strands have to be cut  
(C) No strand needs to be cut  
(D) ATP is required for inter-conversion  
 
Q.32 Let ?? = {??,??,…, ???? } . Let ?? ? ?? consist of all 
prime numbers, ?? ? ??  consist of all even 
numbers and ?? ? ?? consist of all multiples of 
3. Let ?? = ?? - ?? . Then, which of the following 
is/are CORRECT?  
(A) |?? | = 5 ?????? |?? ? ?? | = 9 
(B) |?? | = 6 ?????? |?? ? ?? | = 9  
(C) |?? | = 5?????? |?? n ?? | = 1  
(D) |?? | = 6 ?????? |?? n ?? | = 1  
  
 
Q.33 Let ?? = (?? ) = (?? - ?? )(?? - ?? )(?? - ?? )(?? -
?? )?????? ?????? ?= ?? (
?? ?? ),?? = ?? (
?? ?? )?????? ?? =
?? (
?? ?? ).  
Which of the following is/are CORRECT?  
(A) ? and ?? have the same sign  
(B) ? and ?? have the same sign  
(C) ?? and ?? have the same sign  
(D) ? ?? and ???? have the same sign  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Q.34 The characteristic oxygen binding profile of 
hemoglobin shown below arises due to the 
________.  
  
(A) quaternary structure  
(B) subunit dissociation  
(C) cooperativity  
(D) conformational change  
 
 
Q.35 The advantage(s) of storing chemical energy in 
the form of starch and not as free glucose 
is/are that it________.  
(A) minimizes diffusion  
(B) enables compact storage  
(C) reduces osmotic pressure  
(D) protects against chemical reactivity of 
aldehyde groups  
 
Q.36 Which of the following cell types can develop 
from myeloid lineage?  
(A) Macrophages  
(B) T lymphocytes  
(C) B lymphocytes  
(D) Erythrocytes  
 
Q.37 Electromagnetic waves _______.  
(A) carry energy  
(B) carry momentum  
(C) are transverse in nature while travelling in 
vacuum  
(D) do not need a material medium to travel  
 
  
Page 5


IIT JAM BIOTECHNOLOGY 2019  
             
 
 
SECTION – A 
MULTIPLE CHOICE QUESTIONS (MCQ) 
Q. 1 – Q.10 carry one mark each. 
 
Q.1 The glycosidic linkages in cellulose and amylose 
are ________, respectively.  
(A) a 1-4 and ß 1-4  
(B) ß 1-4 and a 1-4  
(C) ß 1-4 and a 1-6  
(D) a 1-4 and a 1-2  
 
Q.2 A mutation in the operator locus of lac operon 
that confers constitutive expression of ß-
galactosidase is ________.  
(A) cis dominant  
(B) trans dominant  
(C) co-dominant  
(D) dominant negative 
 
Q.3 Which one of the points ?? = (
?? ?? ,
?? ?? ),?? =
(
?? ?? ,
?? ?? ),?? = (
?? ?? ,
????
?? )?????? ?? = (
????
?? ,
?? ?? ) lies ABOVE 
the parabola ?? = ????
?? and INSIDE the circle ?? ?? +
?? ?? = ??? 
(A) P  
(B) Q  
(C) R  
(D) S 
 
Q.4 Let ?? = {??,??,??,??,?? }  A subset S is chosen 
uniformly at random from the non-empty 
subsets of U. What is the probability that S does 
NOT have two consecutive elements? 
(A) 9/31  
(B) 10/31 
(C) 11/31  
(D) 12/31  
 
Q.5 Which one of the following figures represents 
the correct sequence of phases in adult 
eukaryotic cell cycle? 
 
 
 
 
 
 
 
Q.6 At what pH does poly-Glu in an aqueous solution 
form a-helical structure?  
(A) 3  
(B) 7  
(C) 9  
(D) 12  
 
Q.7 The dimensions of coefficient of viscosity are 
_______.  
(A) ML
-1
T
-1
  
(B) ML
-1
T
-2
  
(C) ML
-2
T
-2
  
(D) ML
-2
T
-1
  
 
Q.8 Match the entries in Group I with the entries in 
Group II  
Group I   Group II  
(P) Nylon    (i) Isoprene  
(Q) Natural rubber   (ii) Hexose  
(R) Starch    (iii) Amino acid  
(S) Myoglobin   (iv) Adipic acid  
(A) P-iv, Q-i, R-ii, S-iii  
(B) P-iv, Q-i, R-iii, S-ii  
(C) P-iv, Q-iii, R-ii, S-i  
(D) P-ii, Q-iv, R-i, S-iii  
 
Q.9 The technique that involves impacting samples 
with electrons is _______.  
(A) NMR spectroscopy  
(B) ESI mass spectrometry  
(C) IR spectroscopy  
(D) UV-vis spectroscopy  
 
Q.10 The orbital angular momentum of hydrogen 
atom in the ground state is ________.  
(A) 0  
(B) 
h
2??  
(C) 
h
2
  
(D) h  
 
  
IIT JAM BIOTECHNOLOGY 2019  
             
 
Q. 11 – Q. 30 carry two marks each. 
 
Q.11 Let ?? =
v?? +?? ?? ???????? =
v?? -?? ?? . Then 
?????? ???8
?? ?? +?? ?? ?? ?? -?? ?? 
(A) is 1  
(B) is ½  
(C) is 0  
(D) does not exist  
 
Q.12 In how many ways can one write the elements 
1, 2, 3, 4 in a sequence ?? ?? ,?? ?? ,?? ?? ,?? ??  with?? ?? ?
?????  
(A) 9  
(B) 10  
(C) 11  
(D) 12 
 
Q.13 Simplify 
???????? ??+???????? +
??+???????? ????????  
(A) 2 sec A  
(B) 2 cosec A   
(C) sec A  
(D) cosec A  
 
Q.14 The evolution of eyes in octopus and in human 
is an example of ________.  
(A) divergent evolution  
(B) convergent evolution  
(C) adaptive radiation  
(D) genetic drift  
 
Q.15 Which one of the following modifications 
occurs both on DNA and protein?  
(A) ADP-ribosylation  
(B) Methylation  
(C) Sumoylation  
(D) Ubiquitination  
 
Q.16 Solutions of the following peptides are 
prepared separately at a concentration of 1 
mM. Among these four, which one has the 
highest A280?  
(A) Ser-Val-Trp-Asp-Phe-Gly-Tyr-Trp-Ala  
(B) Gln-Leu-Glu-Phe-Thr-Leu-Asp-Gly-Tyr  
(C) Met-Gly-Val-Ileu-Asp-Ser-Ala-Trp-His  
(D) His-Pro-Gly-Asp-Val-Ileu-Phe-Met-Leu  
 
Q.17 The free energy required to synthesize a mixed 
anhydride bond of 1,3-bisphosphoglycerate is 
generated by the oxidation of ________.  
(A) an aldehyde to acid  
(B) an alcohol to acid  
(C) an alcohol to aldehyde  
(D) NADH to NAD+  
 
 
Q.18 The following reaction is an example of 
___________.  
  
(A) enolization  
(B) racemization  
(C) isomerization  
(D) epimerization  
 
Q.19 Which one of the following parameters changes 
upon doubling the enzyme concentration?  
(A) K M  
(B) V max  
(C) k cat  
(D) K eq  
 
Q.20 Which one of the following statements is a 
correct description of modes of action of taxol 
and colchicine?  
(A) Taxol causes DNA damage and colchicine 
prevents microtubule formation  
(B) Taxol stabilizes microtubules and colchicine 
inhibits protein synthesis  
(C) Taxol destabilizes microtubules and 
colchicine promotes microtubule formation  
(D) Taxol stabilizes microtubules and colchicine 
prevents microtubule formation  
 
Q.21 In a simple microscope, _______.  
(A) a lens with negative power is used  
(B) the focal length of the lens is less than the 
least distance for clear vision  
(C) the focal length of the lens is greater than 
the least distance for clear vision  
(D) magnification depends only on the focal 
length of the lens 
  
Q.22 Which one of the following statements is 
INCORRECT with respect to bacterial 
conjugation?  
(A) It facilitates transfer of genetic material  
(B) It requires flagellum  
(C) It can spread antibiotic resistance  
(D) It can transfer virulence factors  
 
  
IIT JAM BIOTECHNOLOGY 2019  
             
 
 
Q.23 A particle starting from rest is subjected to a 
constant force. The plot of distance traveled 
along the direction of the force as a function of 
time is a/an ______.  
(A) straight line  
(B) circle  
(C) parabola  
(D) ellipse  
 
Q.24 Indole acetic acid (IAA) is involved in ______.  
(A) gravitropism  
(B) flowering  
(C) ripening  
(D) senescence  
 
Q.25 Which one of the following remains unchanged 
when light waves enter water from air?  
(A) Wavelength  
(B) Wavenumber  
(C) Frequency  
(D) Intensity  
 
Q.26 According to the kinetic theory of gases, the 
average energy of a diatomic molecule in an 
ideal gas depends on _______.  
(A) mass of each atom and the temperature  
(B) mass of each atom and the bond length  
(C) mass of each atom, bond length, and 
temperature  
(D) temperature only  
 
Q.27 Match the entries in Group I with entries in 
Group II  
Group I    Group II  
(P) Bacteria   (i) Malaria  
(Q) Virus    (ii) Tuberculosis  
(R) Protozoa   (iii) Influenza  
(S) Autoantibodies  (iv) Myasthenia gravis 
(A) P-ii, Q-i, R-iii, S-iv  
(B) P-ii, Q-iii, R-i, S-iv  
(C) P-iv, Q-iii, R-i, S-ii  
(D) P-i, Q-iv, R-ii, S-iii  
 
Q.28 pKa increases in the order _______.  
(A) HN 3 > NH 3OH
+
 > N 2H 5
+
 > NH 3  
(B) NH 3OH
+
 > N 2H 5
+
 > HN 3 > NH 3  
(C) NH 3 > NH 3OH+ > N 2H 5
+
 > HN 3  
(D) HN 3 > N 2H 5
+
 > NH 3 > NH 3OH
+
  
 
 
 
 
 
Q.29 H 2 reacts with trans-(Ph 3P) 2Ir(CO)Cl to primarily 
produce _______.  
  
 
 
Q.30 Among the following species, the metal center 
that has the highest number of unpaired 
electrons is _______.  
(A) VCl 4  
(B) Ni(CO) 4  
(C) [AuCl 4]
 ?
  
(D) [CdBr 4]
 2 ?
  
IIT JAM BIOTECHNOLOGY 2019  
             
 
  
 
SECTION -B  
MULTIPLE SELECT QUESTIONS (MSQ) 
 
Q. 31 – Q. 40 carry two marks each.  
 
Q.31 Pick the correct statement(s) with respect to 
the inter-conversion of the topoisomers of a 
circularly closed double stranded DNA.  
(A) Only one strand needs to be cut  
(B) Both strands have to be cut  
(C) No strand needs to be cut  
(D) ATP is required for inter-conversion  
 
Q.32 Let ?? = {??,??,…, ???? } . Let ?? ? ?? consist of all 
prime numbers, ?? ? ??  consist of all even 
numbers and ?? ? ?? consist of all multiples of 
3. Let ?? = ?? - ?? . Then, which of the following 
is/are CORRECT?  
(A) |?? | = 5 ?????? |?? ? ?? | = 9 
(B) |?? | = 6 ?????? |?? ? ?? | = 9  
(C) |?? | = 5?????? |?? n ?? | = 1  
(D) |?? | = 6 ?????? |?? n ?? | = 1  
  
 
Q.33 Let ?? = (?? ) = (?? - ?? )(?? - ?? )(?? - ?? )(?? -
?? )?????? ?????? ?= ?? (
?? ?? ),?? = ?? (
?? ?? )?????? ?? =
?? (
?? ?? ).  
Which of the following is/are CORRECT?  
(A) ? and ?? have the same sign  
(B) ? and ?? have the same sign  
(C) ?? and ?? have the same sign  
(D) ? ?? and ???? have the same sign  
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Q.34 The characteristic oxygen binding profile of 
hemoglobin shown below arises due to the 
________.  
  
(A) quaternary structure  
(B) subunit dissociation  
(C) cooperativity  
(D) conformational change  
 
 
Q.35 The advantage(s) of storing chemical energy in 
the form of starch and not as free glucose 
is/are that it________.  
(A) minimizes diffusion  
(B) enables compact storage  
(C) reduces osmotic pressure  
(D) protects against chemical reactivity of 
aldehyde groups  
 
Q.36 Which of the following cell types can develop 
from myeloid lineage?  
(A) Macrophages  
(B) T lymphocytes  
(C) B lymphocytes  
(D) Erythrocytes  
 
Q.37 Electromagnetic waves _______.  
(A) carry energy  
(B) carry momentum  
(C) are transverse in nature while travelling in 
vacuum  
(D) do not need a material medium to travel  
 
  
IIT JAM BIOTECHNOLOGY 2019  
             
 
 
Q.38 Which of the following statement(s) is/are 
true?  
(A) In intrinsic semiconductors, the number of 
electrons is equal to the number of holes at any 
temperature  
(B) An intrinsic semiconductor changes to an n-
type semiconductor upon addition of a trivalent 
element  
(C) The shape of the I-V characteristics of a p-n 
diode is a straight line  
(D) In the reverse bias condition, the current in 
a p-n diode is due to the minority carriers  
 
Q.39 BF3 reacts readily with ________.  
(A) C 5H 5N  
(B) SnCl 2  
(C) SO 3  
(D) (C 5H 5N) ?SnCl 2  
 
Q.40 The reaction of (R)-2-bromobutane with CN ? 
proceeds by ________.  
(A) retention of configuration  
(B) inversion of configuration  
(C) formation of CH 2=CH(CH 2CH 3)  
(D) formation of (S)-2-methylbutanenitrile