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Page 1 Respiratorymechanicsin Respiratory mechanics in mechanical ventilation ArjunSrinivasan Page 2 Respiratorymechanicsin Respiratory mechanics in mechanical ventilation ArjunSrinivasan • Introduction • Mechanicsduringventilation Mechanics during ventilation • PV curves • Application in health & disease • Difficulties&pitfalls Difficulties & pitfalls • The future…. Page 3 Respiratorymechanicsin Respiratory mechanics in mechanical ventilation ArjunSrinivasan • Introduction • Mechanicsduringventilation Mechanics during ventilation • PV curves • Application in health & disease • Difficulties&pitfalls Difficulties & pitfalls • The future…. MonitoringMechanics Monitoring Mechanics P fl d l • Pressure, flow, and volume • Time-based graphics (waveforms) P – Pressure – Flow – Volume Volume • Derived measures – Compliance p – Resistance • Loops – Pressure volume – Flow volume Page 4 Respiratorymechanicsin Respiratory mechanics in mechanical ventilation ArjunSrinivasan • Introduction • Mechanicsduringventilation Mechanics during ventilation • PV curves • Application in health & disease • Difficulties&pitfalls Difficulties & pitfalls • The future…. MonitoringMechanics Monitoring Mechanics P fl d l • Pressure, flow, and volume • Time-based graphics (waveforms) P – Pressure – Flow – Volume Volume • Derived measures – Compliance p – Resistance • Loops – Pressure volume – Flow volume Pressures Pressures • Peak inspiratorypressure (PIP) – Pressure generated to drive gas into the lungs to overcome resistance & elastic property of RS – Dependant on flow, resistance, TV, compliance & PEEP – Slope of the curve depends on flow pattern • Plateaupressure(P ) • Plateau pressure( P plat ) – Measured after E ins pause of ~2 secs R ll – Represents alveolar pressure – True inflation pressure Page 5 Respiratorymechanicsin Respiratory mechanics in mechanical ventilation ArjunSrinivasan • Introduction • Mechanicsduringventilation Mechanics during ventilation • PV curves • Application in health & disease • Difficulties&pitfalls Difficulties & pitfalls • The future…. MonitoringMechanics Monitoring Mechanics P fl d l • Pressure, flow, and volume • Time-based graphics (waveforms) P – Pressure – Flow – Volume Volume • Derived measures – Compliance p – Resistance • Loops – Pressure volume – Flow volume Pressures Pressures • Peak inspiratorypressure (PIP) – Pressure generated to drive gas into the lungs to overcome resistance & elastic property of RS – Dependant on flow, resistance, TV, compliance & PEEP – Slope of the curve depends on flow pattern • Plateaupressure(P ) • Plateau pressure( P plat ) – Measured after E ins pause of ~2 secs R ll – Represents alveolar pressure – True inflation pressure PEEP PEEP i P f ii P E i h b fPEEP • Presence of positive P aw at E exp in the absence of PEEP E • Measured by application of E exp pause • Etiology – Dynamic hyperinflation with airflow obstruction – Dynamic hyperinflation without airflow obstruction – Without either Ld • Leads to – Hyperinflation-volutrauma D ti iti it fti – Decreases trigger sensitivity-fatigue – Hemodynamic compromiseRead More