Respiratory Mechanics In Mechanical Ventilation

Respiratory Mechanics In Mechanical Ventilation

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 Page 1


Respiratorymechanicsin Respiratory mechanics in 
mechanical ventilation
ArjunSrinivasan
Page 2


Respiratorymechanicsin Respiratory mechanics in 
mechanical ventilation
ArjunSrinivasan
• Introduction
• Mechanicsduringventilation Mechanics during ventilation
• PV curves
• Application in health & disease
• Difficulties&pitfalls Difficulties & pitfalls
• The future….
Page 3


Respiratorymechanicsin Respiratory mechanics in 
mechanical ventilation
ArjunSrinivasan
• Introduction
• Mechanicsduringventilation Mechanics during ventilation
• PV curves
• Application in health & disease
• Difficulties&pitfalls Difficulties & pitfalls
• The future….
MonitoringMechanics Monitoring Mechanics 
P fl d l • Pressure, flow, and volume 
• Time-based graphics (waveforms)
P – Pressure
– Flow
– Volume Volume
• Derived measures
– Compliance p
– Resistance
• Loops
– Pressure volume 
– Flow volume
Page 4


Respiratorymechanicsin Respiratory mechanics in 
mechanical ventilation
ArjunSrinivasan
• Introduction
• Mechanicsduringventilation Mechanics during ventilation
• PV curves
• Application in health & disease
• Difficulties&pitfalls Difficulties & pitfalls
• The future….
MonitoringMechanics Monitoring Mechanics 
P fl d l • Pressure, flow, and volume 
• Time-based graphics (waveforms)
P – Pressure
– Flow
– Volume Volume
• Derived measures
– Compliance p
– Resistance
• Loops
– Pressure volume 
– Flow volume
Pressures Pressures 
• Peak inspiratorypressure (PIP)
– Pressure generated to drive gas into the lungs to 
overcome resistance & elastic  property of RS
– Dependant on flow, resistance, TV, compliance & PEEP
– Slope of the curve depends on flow pattern
• Plateaupressure(P ) • Plateau pressure( P
plat
)
– Measured after E
ins
pause of ~2 secs
R ll – Represents alveolar pressure
– True inflation pressure
Page 5


Respiratorymechanicsin Respiratory mechanics in 
mechanical ventilation
ArjunSrinivasan
• Introduction
• Mechanicsduringventilation Mechanics during ventilation
• PV curves
• Application in health & disease
• Difficulties&pitfalls Difficulties & pitfalls
• The future….
MonitoringMechanics Monitoring Mechanics 
P fl d l • Pressure, flow, and volume 
• Time-based graphics (waveforms)
P – Pressure
– Flow
– Volume Volume
• Derived measures
– Compliance p
– Resistance
• Loops
– Pressure volume 
– Flow volume
Pressures Pressures 
• Peak inspiratorypressure (PIP)
– Pressure generated to drive gas into the lungs to 
overcome resistance & elastic  property of RS
– Dependant on flow, resistance, TV, compliance & PEEP
– Slope of the curve depends on flow pattern
• Plateaupressure(P ) • Plateau pressure( P
plat
)
– Measured after E
ins
pause of ~2 secs
R ll – Represents alveolar pressure
– True inflation pressure
PEEP PEEP
i
P f ii P E i h b fPEEP • Presence of positive P
aw 
at E
exp
in the absence of PEEP
E
• Measured by application of E
exp
pause
• Etiology
– Dynamic hyperinflation with airflow obstruction
– Dynamic hyperinflation without airflow obstruction
– Without either
Ld • Leads to 
– Hyperinflation-volutrauma
D ti iti it fti – Decreases trigger sensitivity-fatigue
– Hemodynamic compromise
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