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In an antigen antibody interaction in the zone of equivalence, the isolated antigen IgA complex was found to be in the molar ratio of antigen : IgA, 2 : 1. The number of epitopes present on the antigen is/are_____.
Correct answer is '1'. Can you explain this answer?
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In an antigen antibody interaction in the zone of equivalence, the iso...
Antigen-Antibody Interaction in the Zone of Equivalence
In an antigen-antibody interaction, the zone of equivalence refers to a situation where the amount of antigen and antibody in a solution is balanced. This means that all the antigen molecules present in the solution are bound by the antibodies, forming antigen-antibody complexes. In this zone, the reaction reaches its maximum, and precipitation or agglutination occurs.
Isolated Antigen IgA complex in a 2:1 Molar Ratio
In the given scenario, the isolated antigen IgA complex was found to be in a molar ratio of antigen to IgA of 2:1. This means that for every 2 antigen molecules, there is 1 IgA molecule present in the complex.
To understand the number of epitopes present on the antigen, we need to consider the concept of valency. Valency refers to the number of binding sites or epitopes present on an antigen. The valency of an antigen determines the number of antibody molecules that can bind to it.
Epitopes and Valency
Epitopes are specific regions on an antigen molecule that bind to antibodies. Each epitope can bind to one antibody molecule. Therefore, the number of epitopes present on an antigen is equal to its valency.
In the given scenario, the molar ratio of antigen to IgA is 2:1. This means that for every 2 antigen molecules, there is 1 IgA molecule present in the complex. Since the ratio is 2:1, it indicates that each antigen molecule is bound by only one IgA molecule.
Conclusion
Based on the 2:1 molar ratio of antigen to IgA in the isolated antigen IgA complex, we can conclude that there is only one epitope present on the antigen. This is because each antigen molecule is bound by one IgA molecule, indicating that each antigen molecule has only one binding site or epitope.
Therefore, the correct answer to the question "The number of epitopes present on the antigen is/are _____" is '1'.
In an antigen-antibody interaction, the zone of equivalence refers to a situation where the amount of antigen and antibody in a solution is balanced. This means that all the antigen molecules present in the solution are bound by the antibodies, forming antigen-antibody complexes. In this zone, the reaction reaches its maximum, and precipitation or agglutination occurs.
Isolated Antigen IgA complex in a 2:1 Molar Ratio
In the given scenario, the isolated antigen IgA complex was found to be in a molar ratio of antigen to IgA of 2:1. This means that for every 2 antigen molecules, there is 1 IgA molecule present in the complex.
To understand the number of epitopes present on the antigen, we need to consider the concept of valency. Valency refers to the number of binding sites or epitopes present on an antigen. The valency of an antigen determines the number of antibody molecules that can bind to it.
Epitopes and Valency
Epitopes are specific regions on an antigen molecule that bind to antibodies. Each epitope can bind to one antibody molecule. Therefore, the number of epitopes present on an antigen is equal to its valency.
In the given scenario, the molar ratio of antigen to IgA is 2:1. This means that for every 2 antigen molecules, there is 1 IgA molecule present in the complex. Since the ratio is 2:1, it indicates that each antigen molecule is bound by only one IgA molecule.
Conclusion
Based on the 2:1 molar ratio of antigen to IgA in the isolated antigen IgA complex, we can conclude that there is only one epitope present on the antigen. This is because each antigen molecule is bound by one IgA molecule, indicating that each antigen molecule has only one binding site or epitope.
Therefore, the correct answer to the question "The number of epitopes present on the antigen is/are _____" is '1'.
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In an antigen antibody interaction in the zone of equivalence, the isolated antigen IgA complex was found to be in the molar ratio of antigen : IgA, 2 : 1. The number of epitopes present on the antigen is/are_____.Correct answer is '1'. Can you explain this answer?
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