Disinfection in hospital practice Notes | EduRev

: Disinfection in hospital practice Notes | EduRev

 Page 1


Dr.T.V.Rao MD 
DISINFECTION IN HOSPITALS 
DR.T.V.RAO MD 1 
Page 2


Dr.T.V.Rao MD 
DISINFECTION IN HOSPITALS 
DR.T.V.RAO MD 1 
WHAT IS DISINFECTION  
• Disinfection may be defined as: Cleaning an 
article of some or all of the pathogenic 
organisms which may cause infection  
• Perfect disinfectant would also offer complete 
and full sterilization, without harming other forms 
of life, be inexpensive, and non-corrosive. 
Unfortunately ideal disinfectants do not exist. 
Most disinfectants are also, by their very nature, 
potentially harmful (even toxic) to humans or 
animals.  
DR.T.V.RAO MD 2 
Page 3


Dr.T.V.Rao MD 
DISINFECTION IN HOSPITALS 
DR.T.V.RAO MD 1 
WHAT IS DISINFECTION  
• Disinfection may be defined as: Cleaning an 
article of some or all of the pathogenic 
organisms which may cause infection  
• Perfect disinfectant would also offer complete 
and full sterilization, without harming other forms 
of life, be inexpensive, and non-corrosive. 
Unfortunately ideal disinfectants do not exist. 
Most disinfectants are also, by their very nature, 
potentially harmful (even toxic) to humans or 
animals.  
DR.T.V.RAO MD 2 
THE IDEAL DISINFECTANT 
? Resistant to inactivation 
? Broadly active (killing pathogens) 
? Not poisonous (or otherwise harmful) 
? Penetrating (to pathogens) 
? Not damaging to non-living materials 
? Stable 
? Easy to work with 
? Otherwise not unpleasant 
DR.T.V.RAO MD 3 
Page 4


Dr.T.V.Rao MD 
DISINFECTION IN HOSPITALS 
DR.T.V.RAO MD 1 
WHAT IS DISINFECTION  
• Disinfection may be defined as: Cleaning an 
article of some or all of the pathogenic 
organisms which may cause infection  
• Perfect disinfectant would also offer complete 
and full sterilization, without harming other forms 
of life, be inexpensive, and non-corrosive. 
Unfortunately ideal disinfectants do not exist. 
Most disinfectants are also, by their very nature, 
potentially harmful (even toxic) to humans or 
animals.  
DR.T.V.RAO MD 2 
THE IDEAL DISINFECTANT 
? Resistant to inactivation 
? Broadly active (killing pathogens) 
? Not poisonous (or otherwise harmful) 
? Penetrating (to pathogens) 
? Not damaging to non-living materials 
? Stable 
? Easy to work with 
? Otherwise not unpleasant 
DR.T.V.RAO MD 3 
WHY DISINFECTION AND STERILIZATION? 
• Contagious diseases 
• Hospital infection (e.g., OR, ID ward) or other opportunistic 
infection  
• Lab contamination 
• Etc.  
• Microbes: 
- usually easy to grow in environment;  
- but also can be inhibited or killed by certain environmental (physical or 
chemical) factors/conditions.  
DR.T.V.RAO MD 4 
Page 5


Dr.T.V.Rao MD 
DISINFECTION IN HOSPITALS 
DR.T.V.RAO MD 1 
WHAT IS DISINFECTION  
• Disinfection may be defined as: Cleaning an 
article of some or all of the pathogenic 
organisms which may cause infection  
• Perfect disinfectant would also offer complete 
and full sterilization, without harming other forms 
of life, be inexpensive, and non-corrosive. 
Unfortunately ideal disinfectants do not exist. 
Most disinfectants are also, by their very nature, 
potentially harmful (even toxic) to humans or 
animals.  
DR.T.V.RAO MD 2 
THE IDEAL DISINFECTANT 
? Resistant to inactivation 
? Broadly active (killing pathogens) 
? Not poisonous (or otherwise harmful) 
? Penetrating (to pathogens) 
? Not damaging to non-living materials 
? Stable 
? Easy to work with 
? Otherwise not unpleasant 
DR.T.V.RAO MD 3 
WHY DISINFECTION AND STERILIZATION? 
• Contagious diseases 
• Hospital infection (e.g., OR, ID ward) or other opportunistic 
infection  
• Lab contamination 
• Etc.  
• Microbes: 
- usually easy to grow in environment;  
- but also can be inhibited or killed by certain environmental (physical or 
chemical) factors/conditions.  
DR.T.V.RAO MD 4 
TERMINOLOGY 
• Antisepsis: chemical destruction of 
vegetative pathogens on living tissue 
• Degerming: mechanical removal of 
microbes from limited area 
• Sanitization: lowering microbial counts 
on eating and drinking utensils to safe 
levels 
DR.T.V.RAO MD 5 
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