MCQ Test: Molecular Basis of Inheritance NEET Notes | EduRev

NEET : MCQ Test: Molecular Basis of Inheritance NEET Notes | EduRev

 Page 1


ADHAR INSTITUTE 
  We say what we do 
SCO-350, Sec-34 A, Chandigarh,  Phone Nos. 9216777953,  7837779254 
 
 Molecular Basis of Inheritance 
 ( LEVEL – 2 ) 
Time Allowed : 2 hours         Marks Obtained _________,   Total Marks : 50    
 
Student’s Name ________________             Phone No’s______________ 
 
( OBJECTIVE BIOLOGY ) 
1. 1ength of one loop of  B DNA 
(a)   3.4 nm    (b)  0.34 nm 
(c)   20 nm    (d)  10 nm 
2. In negative operon 
(a) corepressor binds with repressor 
(b) corepressor does not bind with repressor 
(c) corepressor binds with inducer 
(d) CAMP have negative effect on lac operon 
3. What would happen if in a gene encoding a polypeptide 50 amino acids, 25"' codon (UAU) is mutated 
to UAA ? 
(a) a polypeptide of  24 amino acids will be formed 
(b) two polypeptides of  24and 25 amino acids will formed 
(c) a polypeptide of 49 amino acids will be formed 
(d) a polypeptide of 25 amino acids will be formed 
4. During transcription, if the nucleotide sequence of the DNA strand that is being coded is ATACG then 
the nucleotide sequence in the mRNA would be 
(a) AAAT box    (b) TATA box 
(c) GGTT box    (d) CAAT box 
5. Which one of the following triplet codes, is correctly matched with its specificity for an amino acid in 
protein synthesis or as ‘start’ or ‘stop’ codon ? 
(a) UCG – start    (b) UUU stop 
(c) UGU – leucine   (d) UAC – tyrosine 
6. Which one of the following correctly represents the manner of replication of DNA ? 
 
                     Be Determined Towards Your Goal 
Page 2


ADHAR INSTITUTE 
  We say what we do 
SCO-350, Sec-34 A, Chandigarh,  Phone Nos. 9216777953,  7837779254 
 
 Molecular Basis of Inheritance 
 ( LEVEL – 2 ) 
Time Allowed : 2 hours         Marks Obtained _________,   Total Marks : 50    
 
Student’s Name ________________             Phone No’s______________ 
 
( OBJECTIVE BIOLOGY ) 
1. 1ength of one loop of  B DNA 
(a)   3.4 nm    (b)  0.34 nm 
(c)   20 nm    (d)  10 nm 
2. In negative operon 
(a) corepressor binds with repressor 
(b) corepressor does not bind with repressor 
(c) corepressor binds with inducer 
(d) CAMP have negative effect on lac operon 
3. What would happen if in a gene encoding a polypeptide 50 amino acids, 25"' codon (UAU) is mutated 
to UAA ? 
(a) a polypeptide of  24 amino acids will be formed 
(b) two polypeptides of  24and 25 amino acids will formed 
(c) a polypeptide of 49 amino acids will be formed 
(d) a polypeptide of 25 amino acids will be formed 
4. During transcription, if the nucleotide sequence of the DNA strand that is being coded is ATACG then 
the nucleotide sequence in the mRNA would be 
(a) AAAT box    (b) TATA box 
(c) GGTT box    (d) CAAT box 
5. Which one of the following triplet codes, is correctly matched with its specificity for an amino acid in 
protein synthesis or as ‘start’ or ‘stop’ codon ? 
(a) UCG – start    (b) UUU stop 
(c) UGU – leucine   (d) UAC – tyrosine 
6. Which one of the following correctly represents the manner of replication of DNA ? 
 
                     Be Determined Towards Your Goal 
                                           For Success attitude is equally as important as ability 
7. The codon for anticodon 3'-UUUA-5' is  
(a)   5'-UAAA3'   (b) 3'-AAAU5' 
(c)   5'AAAU3'   (d) 3'-UAAD5' 
8. Base composition in RNA is 
(a) A +T =G + C   (b) A +G =T +C 
(c) A + U = G + C   (d) A + G = U + C 
9. DNA and RNA differ by 
(a) N-bases and phosphate groups 
(b) number of C-atoms in sugars 
(c) N-bases and sugar 
(d) sugar and phosphate groups 
10. Which DNA molecule among the following will melt at lowest temperature ? 
(a)   5'-A-A-T-G-C-T-G-C-3' 
 3'-T-T-A-C-G-A-C-G-5' 
(b)  5'-A-A-T-A-A-A-G-C-T-3'  
3'-T-T-A-T-T-T-C-G-A-5' 
(c)  5'-G-C-A-T-A-G-C-T-3' 
 3'-C-G-T-A-T-C-G-A-5' 
(d)  5'-A-T-G-C-T-G-A-T-3'  
3'-T-A-C-G-A-C-T-A-5' 
11. The antiparallel nature of DNA refers to 
(a) its charged phosphate groups 
(b) the formation of hydrogen bonds between bases from opposite strands 
(c) the opposite direction of the two strands 
(d) the pairing of bases on one strand with bases on the outer strand. 
12. Unwinding due to release of coiling tension ahead of moving replication fork is due to 
(a)   topoisomerases   (b) ligase\ 
(c)  helicase    (d) DNA polymerase 
13. Choose the odd statement for RNA. 
(a) sugar moiety is ribose 
(b) uracil replaces thymine 
(c) single stranded 
(d) exclusive to viruses. 
14. Which is not related with eukaryotic mRNA ? 
(a)  intron, exon    (b) ribosomes binding site 
(c)   poly A tail    (d) Okazaki piece. 
15. The process in which DNA of a bacterial cell is transferred into another bacterial cell by virus 
is called  
(a)   transduction   (b) transformation 
(c)   conjugation   (d) reproduction 
                     Be Determined Towards Your Goal 
Page 3


ADHAR INSTITUTE 
  We say what we do 
SCO-350, Sec-34 A, Chandigarh,  Phone Nos. 9216777953,  7837779254 
 
 Molecular Basis of Inheritance 
 ( LEVEL – 2 ) 
Time Allowed : 2 hours         Marks Obtained _________,   Total Marks : 50    
 
Student’s Name ________________             Phone No’s______________ 
 
( OBJECTIVE BIOLOGY ) 
1. 1ength of one loop of  B DNA 
(a)   3.4 nm    (b)  0.34 nm 
(c)   20 nm    (d)  10 nm 
2. In negative operon 
(a) corepressor binds with repressor 
(b) corepressor does not bind with repressor 
(c) corepressor binds with inducer 
(d) CAMP have negative effect on lac operon 
3. What would happen if in a gene encoding a polypeptide 50 amino acids, 25"' codon (UAU) is mutated 
to UAA ? 
(a) a polypeptide of  24 amino acids will be formed 
(b) two polypeptides of  24and 25 amino acids will formed 
(c) a polypeptide of 49 amino acids will be formed 
(d) a polypeptide of 25 amino acids will be formed 
4. During transcription, if the nucleotide sequence of the DNA strand that is being coded is ATACG then 
the nucleotide sequence in the mRNA would be 
(a) AAAT box    (b) TATA box 
(c) GGTT box    (d) CAAT box 
5. Which one of the following triplet codes, is correctly matched with its specificity for an amino acid in 
protein synthesis or as ‘start’ or ‘stop’ codon ? 
(a) UCG – start    (b) UUU stop 
(c) UGU – leucine   (d) UAC – tyrosine 
6. Which one of the following correctly represents the manner of replication of DNA ? 
 
                     Be Determined Towards Your Goal 
                                           For Success attitude is equally as important as ability 
7. The codon for anticodon 3'-UUUA-5' is  
(a)   5'-UAAA3'   (b) 3'-AAAU5' 
(c)   5'AAAU3'   (d) 3'-UAAD5' 
8. Base composition in RNA is 
(a) A +T =G + C   (b) A +G =T +C 
(c) A + U = G + C   (d) A + G = U + C 
9. DNA and RNA differ by 
(a) N-bases and phosphate groups 
(b) number of C-atoms in sugars 
(c) N-bases and sugar 
(d) sugar and phosphate groups 
10. Which DNA molecule among the following will melt at lowest temperature ? 
(a)   5'-A-A-T-G-C-T-G-C-3' 
 3'-T-T-A-C-G-A-C-G-5' 
(b)  5'-A-A-T-A-A-A-G-C-T-3'  
3'-T-T-A-T-T-T-C-G-A-5' 
(c)  5'-G-C-A-T-A-G-C-T-3' 
 3'-C-G-T-A-T-C-G-A-5' 
(d)  5'-A-T-G-C-T-G-A-T-3'  
3'-T-A-C-G-A-C-T-A-5' 
11. The antiparallel nature of DNA refers to 
(a) its charged phosphate groups 
(b) the formation of hydrogen bonds between bases from opposite strands 
(c) the opposite direction of the two strands 
(d) the pairing of bases on one strand with bases on the outer strand. 
12. Unwinding due to release of coiling tension ahead of moving replication fork is due to 
(a)   topoisomerases   (b) ligase\ 
(c)  helicase    (d) DNA polymerase 
13. Choose the odd statement for RNA. 
(a) sugar moiety is ribose 
(b) uracil replaces thymine 
(c) single stranded 
(d) exclusive to viruses. 
14. Which is not related with eukaryotic mRNA ? 
(a)  intron, exon    (b) ribosomes binding site 
(c)   poly A tail    (d) Okazaki piece. 
15. The process in which DNA of a bacterial cell is transferred into another bacterial cell by virus 
is called  
(a)   transduction   (b) transformation 
(c)   conjugation   (d) reproduction 
                     Be Determined Towards Your Goal 
                                           For Success attitude is equally as important as ability 
16. If % age of cytosine is 18%, then %age of adenine will be 
(a) 32%     (b) 34% 
(c) 36%     (d) 23% 
17. Find the sequence of binding of the following amino acyl – t RNA complexes during 
translation of a mRNA transcribed by a DNA segment having the base sequence 3' 
TACATGGGTCCG 5'. Choose the answer showing the correct order of alphabets. 
 
(a)  a, b, d, c      (b) b, a,d, c  
(c)  a,b,c,d    (d) b,a,c.d 
18. Which sequence of codons specifies for leucine-threonine-proline? 
(a)  CUC-GCU-CCC      (b) AAA-ACC-CCC 
(c)  UUG-AGC-UAG    (d) CUA-ACA-CCU 
19. Anticodon is a base triplet on 
(a) mRNA complementary to base sequence on rRNA 
(b) mRNA complementary to base sequence on tRNA 
(c) tRNA complementary to base sequence on rRNA 
(d) tRNA complementary to base sequence on mRNA 
20. How many base pairs are present in one turn of DNA? 
(a)   10     (b) 11 
(c)  9     (d) 12 
21. Operon system consists of 
(a) operator and regulator genes 
(b) operator, regulator, repressor genes 
(c) operator, regulator, repressor, structural and prom genes 
(d) none of the above 
22. Identify the pair of nucleotides which are joined by 3 hydrogen bonds in double stranded 
DNA 
(a)  AG     (b) AT 
(c)  TG     (d) CG 
23. DNA synthesis can be specifically measured by estim the incorporation of radio-labelled 
(a)  uracil    (b) adenine 
(c)   thymine    (d) deoxyribose sugar. 
24. If a segment of an mRNA molecule has the sequence 5' GUACCGAUCG 3'. which of the 
following could have been the template DNA molecule 
(a) 5'GCUAGCCAUG 3'  (b) 5'GUACCGAUCG 3' 
(c) 5' CATGGCTAGC 3'  (d) 5' CGATCGGTAC 3' 
25. Removal of RNA polymerase III from nucleoplasm will affect , the synthesis of 
(a)   t RNA    (b)   hnRNA 
                     Be Determined Towards Your Goal 
Page 4


ADHAR INSTITUTE 
  We say what we do 
SCO-350, Sec-34 A, Chandigarh,  Phone Nos. 9216777953,  7837779254 
 
 Molecular Basis of Inheritance 
 ( LEVEL – 2 ) 
Time Allowed : 2 hours         Marks Obtained _________,   Total Marks : 50    
 
Student’s Name ________________             Phone No’s______________ 
 
( OBJECTIVE BIOLOGY ) 
1. 1ength of one loop of  B DNA 
(a)   3.4 nm    (b)  0.34 nm 
(c)   20 nm    (d)  10 nm 
2. In negative operon 
(a) corepressor binds with repressor 
(b) corepressor does not bind with repressor 
(c) corepressor binds with inducer 
(d) CAMP have negative effect on lac operon 
3. What would happen if in a gene encoding a polypeptide 50 amino acids, 25"' codon (UAU) is mutated 
to UAA ? 
(a) a polypeptide of  24 amino acids will be formed 
(b) two polypeptides of  24and 25 amino acids will formed 
(c) a polypeptide of 49 amino acids will be formed 
(d) a polypeptide of 25 amino acids will be formed 
4. During transcription, if the nucleotide sequence of the DNA strand that is being coded is ATACG then 
the nucleotide sequence in the mRNA would be 
(a) AAAT box    (b) TATA box 
(c) GGTT box    (d) CAAT box 
5. Which one of the following triplet codes, is correctly matched with its specificity for an amino acid in 
protein synthesis or as ‘start’ or ‘stop’ codon ? 
(a) UCG – start    (b) UUU stop 
(c) UGU – leucine   (d) UAC – tyrosine 
6. Which one of the following correctly represents the manner of replication of DNA ? 
 
                     Be Determined Towards Your Goal 
                                           For Success attitude is equally as important as ability 
7. The codon for anticodon 3'-UUUA-5' is  
(a)   5'-UAAA3'   (b) 3'-AAAU5' 
(c)   5'AAAU3'   (d) 3'-UAAD5' 
8. Base composition in RNA is 
(a) A +T =G + C   (b) A +G =T +C 
(c) A + U = G + C   (d) A + G = U + C 
9. DNA and RNA differ by 
(a) N-bases and phosphate groups 
(b) number of C-atoms in sugars 
(c) N-bases and sugar 
(d) sugar and phosphate groups 
10. Which DNA molecule among the following will melt at lowest temperature ? 
(a)   5'-A-A-T-G-C-T-G-C-3' 
 3'-T-T-A-C-G-A-C-G-5' 
(b)  5'-A-A-T-A-A-A-G-C-T-3'  
3'-T-T-A-T-T-T-C-G-A-5' 
(c)  5'-G-C-A-T-A-G-C-T-3' 
 3'-C-G-T-A-T-C-G-A-5' 
(d)  5'-A-T-G-C-T-G-A-T-3'  
3'-T-A-C-G-A-C-T-A-5' 
11. The antiparallel nature of DNA refers to 
(a) its charged phosphate groups 
(b) the formation of hydrogen bonds between bases from opposite strands 
(c) the opposite direction of the two strands 
(d) the pairing of bases on one strand with bases on the outer strand. 
12. Unwinding due to release of coiling tension ahead of moving replication fork is due to 
(a)   topoisomerases   (b) ligase\ 
(c)  helicase    (d) DNA polymerase 
13. Choose the odd statement for RNA. 
(a) sugar moiety is ribose 
(b) uracil replaces thymine 
(c) single stranded 
(d) exclusive to viruses. 
14. Which is not related with eukaryotic mRNA ? 
(a)  intron, exon    (b) ribosomes binding site 
(c)   poly A tail    (d) Okazaki piece. 
15. The process in which DNA of a bacterial cell is transferred into another bacterial cell by virus 
is called  
(a)   transduction   (b) transformation 
(c)   conjugation   (d) reproduction 
                     Be Determined Towards Your Goal 
                                           For Success attitude is equally as important as ability 
16. If % age of cytosine is 18%, then %age of adenine will be 
(a) 32%     (b) 34% 
(c) 36%     (d) 23% 
17. Find the sequence of binding of the following amino acyl – t RNA complexes during 
translation of a mRNA transcribed by a DNA segment having the base sequence 3' 
TACATGGGTCCG 5'. Choose the answer showing the correct order of alphabets. 
 
(a)  a, b, d, c      (b) b, a,d, c  
(c)  a,b,c,d    (d) b,a,c.d 
18. Which sequence of codons specifies for leucine-threonine-proline? 
(a)  CUC-GCU-CCC      (b) AAA-ACC-CCC 
(c)  UUG-AGC-UAG    (d) CUA-ACA-CCU 
19. Anticodon is a base triplet on 
(a) mRNA complementary to base sequence on rRNA 
(b) mRNA complementary to base sequence on tRNA 
(c) tRNA complementary to base sequence on rRNA 
(d) tRNA complementary to base sequence on mRNA 
20. How many base pairs are present in one turn of DNA? 
(a)   10     (b) 11 
(c)  9     (d) 12 
21. Operon system consists of 
(a) operator and regulator genes 
(b) operator, regulator, repressor genes 
(c) operator, regulator, repressor, structural and prom genes 
(d) none of the above 
22. Identify the pair of nucleotides which are joined by 3 hydrogen bonds in double stranded 
DNA 
(a)  AG     (b) AT 
(c)  TG     (d) CG 
23. DNA synthesis can be specifically measured by estim the incorporation of radio-labelled 
(a)  uracil    (b) adenine 
(c)   thymine    (d) deoxyribose sugar. 
24. If a segment of an mRNA molecule has the sequence 5' GUACCGAUCG 3'. which of the 
following could have been the template DNA molecule 
(a) 5'GCUAGCCAUG 3'  (b) 5'GUACCGAUCG 3' 
(c) 5' CATGGCTAGC 3'  (d) 5' CGATCGGTAC 3' 
25. Removal of RNA polymerase III from nucleoplasm will affect , the synthesis of 
(a)   t RNA    (b)   hnRNA 
                     Be Determined Towards Your Goal 
                                           For Success attitude is equally as important as ability 
(c)   mRNA    (d) rRNA 
26. In mRNA. AUG is the initiation codon and UAA. UAG at UGA are termination codons. 
therefore polypeptide cannot be synthesized beyond any of these triplets to the end of mRNA. 
Then which one of the following mRNA can be translated completely 
(a) AUG UUC UCC UGG UAA UAU (b) AUG UUC UCC UGA UGG UAU 
(c) AUC ACG UAU UUC UGA CUC (d) AUG UAU UUC UGC CUC UAG 
27. Consider the following statements 
(i) r-RNA provides the template for synthesis of proteins 
(ii) t-RNA brings amino acids and reads the genetic code 
(iii) RNA polymerase binds to promoter and initiates transcription 
(iv) A segment of DNA coding for polypeptide is called intron 
(a) A) and (C) are correct 
(b) (A) and (B) are correct 
(c) (A), (B) and (C) are correct 
(d) (B) and (C) are correct 
(e) (A),(B) and (D) are correct 
28. Locations or sites in the human DNA where single base DNA differences occurs are called 
(a) Repetitive DNA   (b) VNTR 
(c) SNP     (d) SSCP 
(d) Expressed sequence tags 
29. Genes that are involved in turning on or off the transcription of a set of structural genes are 
called 
(a) Polymorphic genes   (b) Operator genes 
(c) Redundant genes   (d) Regulatory genes 
30. Functioning of structural genes is controlled by 
(a) Operator    (b) Promoter 
(c) Ligase    (d) Regulatory gene 
31. Code of m - RNA and proteins are 
 (a) Coplanar     (b) Colinear 
(c) Nonlinear    (d) Irregular 
32. In a given DNA segment ATGACC AGG ACC CCA ACA the first base gets mutated. The 
effect of this on coding by this DNA segment will result in 
(a) Complete change in the type as well as sequence of amino acids 
(b) Change in the first amino acid only 
(c) No change in the sequence 
(d) One amino acid less in the protein 
(e) No coding 
33. Which of the following group of codons code for amino acid serine 
(a) CUU, CUC. CUA and CUG  
(b) UAU, UAC, UGU and UGC 
                     Be Determined Towards Your Goal 
Page 5


ADHAR INSTITUTE 
  We say what we do 
SCO-350, Sec-34 A, Chandigarh,  Phone Nos. 9216777953,  7837779254 
 
 Molecular Basis of Inheritance 
 ( LEVEL – 2 ) 
Time Allowed : 2 hours         Marks Obtained _________,   Total Marks : 50    
 
Student’s Name ________________             Phone No’s______________ 
 
( OBJECTIVE BIOLOGY ) 
1. 1ength of one loop of  B DNA 
(a)   3.4 nm    (b)  0.34 nm 
(c)   20 nm    (d)  10 nm 
2. In negative operon 
(a) corepressor binds with repressor 
(b) corepressor does not bind with repressor 
(c) corepressor binds with inducer 
(d) CAMP have negative effect on lac operon 
3. What would happen if in a gene encoding a polypeptide 50 amino acids, 25"' codon (UAU) is mutated 
to UAA ? 
(a) a polypeptide of  24 amino acids will be formed 
(b) two polypeptides of  24and 25 amino acids will formed 
(c) a polypeptide of 49 amino acids will be formed 
(d) a polypeptide of 25 amino acids will be formed 
4. During transcription, if the nucleotide sequence of the DNA strand that is being coded is ATACG then 
the nucleotide sequence in the mRNA would be 
(a) AAAT box    (b) TATA box 
(c) GGTT box    (d) CAAT box 
5. Which one of the following triplet codes, is correctly matched with its specificity for an amino acid in 
protein synthesis or as ‘start’ or ‘stop’ codon ? 
(a) UCG – start    (b) UUU stop 
(c) UGU – leucine   (d) UAC – tyrosine 
6. Which one of the following correctly represents the manner of replication of DNA ? 
 
                     Be Determined Towards Your Goal 
                                           For Success attitude is equally as important as ability 
7. The codon for anticodon 3'-UUUA-5' is  
(a)   5'-UAAA3'   (b) 3'-AAAU5' 
(c)   5'AAAU3'   (d) 3'-UAAD5' 
8. Base composition in RNA is 
(a) A +T =G + C   (b) A +G =T +C 
(c) A + U = G + C   (d) A + G = U + C 
9. DNA and RNA differ by 
(a) N-bases and phosphate groups 
(b) number of C-atoms in sugars 
(c) N-bases and sugar 
(d) sugar and phosphate groups 
10. Which DNA molecule among the following will melt at lowest temperature ? 
(a)   5'-A-A-T-G-C-T-G-C-3' 
 3'-T-T-A-C-G-A-C-G-5' 
(b)  5'-A-A-T-A-A-A-G-C-T-3'  
3'-T-T-A-T-T-T-C-G-A-5' 
(c)  5'-G-C-A-T-A-G-C-T-3' 
 3'-C-G-T-A-T-C-G-A-5' 
(d)  5'-A-T-G-C-T-G-A-T-3'  
3'-T-A-C-G-A-C-T-A-5' 
11. The antiparallel nature of DNA refers to 
(a) its charged phosphate groups 
(b) the formation of hydrogen bonds between bases from opposite strands 
(c) the opposite direction of the two strands 
(d) the pairing of bases on one strand with bases on the outer strand. 
12. Unwinding due to release of coiling tension ahead of moving replication fork is due to 
(a)   topoisomerases   (b) ligase\ 
(c)  helicase    (d) DNA polymerase 
13. Choose the odd statement for RNA. 
(a) sugar moiety is ribose 
(b) uracil replaces thymine 
(c) single stranded 
(d) exclusive to viruses. 
14. Which is not related with eukaryotic mRNA ? 
(a)  intron, exon    (b) ribosomes binding site 
(c)   poly A tail    (d) Okazaki piece. 
15. The process in which DNA of a bacterial cell is transferred into another bacterial cell by virus 
is called  
(a)   transduction   (b) transformation 
(c)   conjugation   (d) reproduction 
                     Be Determined Towards Your Goal 
                                           For Success attitude is equally as important as ability 
16. If % age of cytosine is 18%, then %age of adenine will be 
(a) 32%     (b) 34% 
(c) 36%     (d) 23% 
17. Find the sequence of binding of the following amino acyl – t RNA complexes during 
translation of a mRNA transcribed by a DNA segment having the base sequence 3' 
TACATGGGTCCG 5'. Choose the answer showing the correct order of alphabets. 
 
(a)  a, b, d, c      (b) b, a,d, c  
(c)  a,b,c,d    (d) b,a,c.d 
18. Which sequence of codons specifies for leucine-threonine-proline? 
(a)  CUC-GCU-CCC      (b) AAA-ACC-CCC 
(c)  UUG-AGC-UAG    (d) CUA-ACA-CCU 
19. Anticodon is a base triplet on 
(a) mRNA complementary to base sequence on rRNA 
(b) mRNA complementary to base sequence on tRNA 
(c) tRNA complementary to base sequence on rRNA 
(d) tRNA complementary to base sequence on mRNA 
20. How many base pairs are present in one turn of DNA? 
(a)   10     (b) 11 
(c)  9     (d) 12 
21. Operon system consists of 
(a) operator and regulator genes 
(b) operator, regulator, repressor genes 
(c) operator, regulator, repressor, structural and prom genes 
(d) none of the above 
22. Identify the pair of nucleotides which are joined by 3 hydrogen bonds in double stranded 
DNA 
(a)  AG     (b) AT 
(c)  TG     (d) CG 
23. DNA synthesis can be specifically measured by estim the incorporation of radio-labelled 
(a)  uracil    (b) adenine 
(c)   thymine    (d) deoxyribose sugar. 
24. If a segment of an mRNA molecule has the sequence 5' GUACCGAUCG 3'. which of the 
following could have been the template DNA molecule 
(a) 5'GCUAGCCAUG 3'  (b) 5'GUACCGAUCG 3' 
(c) 5' CATGGCTAGC 3'  (d) 5' CGATCGGTAC 3' 
25. Removal of RNA polymerase III from nucleoplasm will affect , the synthesis of 
(a)   t RNA    (b)   hnRNA 
                     Be Determined Towards Your Goal 
                                           For Success attitude is equally as important as ability 
(c)   mRNA    (d) rRNA 
26. In mRNA. AUG is the initiation codon and UAA. UAG at UGA are termination codons. 
therefore polypeptide cannot be synthesized beyond any of these triplets to the end of mRNA. 
Then which one of the following mRNA can be translated completely 
(a) AUG UUC UCC UGG UAA UAU (b) AUG UUC UCC UGA UGG UAU 
(c) AUC ACG UAU UUC UGA CUC (d) AUG UAU UUC UGC CUC UAG 
27. Consider the following statements 
(i) r-RNA provides the template for synthesis of proteins 
(ii) t-RNA brings amino acids and reads the genetic code 
(iii) RNA polymerase binds to promoter and initiates transcription 
(iv) A segment of DNA coding for polypeptide is called intron 
(a) A) and (C) are correct 
(b) (A) and (B) are correct 
(c) (A), (B) and (C) are correct 
(d) (B) and (C) are correct 
(e) (A),(B) and (D) are correct 
28. Locations or sites in the human DNA where single base DNA differences occurs are called 
(a) Repetitive DNA   (b) VNTR 
(c) SNP     (d) SSCP 
(d) Expressed sequence tags 
29. Genes that are involved in turning on or off the transcription of a set of structural genes are 
called 
(a) Polymorphic genes   (b) Operator genes 
(c) Redundant genes   (d) Regulatory genes 
30. Functioning of structural genes is controlled by 
(a) Operator    (b) Promoter 
(c) Ligase    (d) Regulatory gene 
31. Code of m - RNA and proteins are 
 (a) Coplanar     (b) Colinear 
(c) Nonlinear    (d) Irregular 
32. In a given DNA segment ATGACC AGG ACC CCA ACA the first base gets mutated. The 
effect of this on coding by this DNA segment will result in 
(a) Complete change in the type as well as sequence of amino acids 
(b) Change in the first amino acid only 
(c) No change in the sequence 
(d) One amino acid less in the protein 
(e) No coding 
33. Which of the following group of codons code for amino acid serine 
(a) CUU, CUC. CUA and CUG  
(b) UAU, UAC, UGU and UGC 
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(c) UCU, UCC, UCA and UCG  
(d) UGU, UGC, UGA and UAG  
(e) GUU, GUC, GCU and GCC 
34. Which conserved   motifs  are  found in E. coli genes 
(a) TATA box    (b) CAAT box 
(c) Pribnow box    (d) All of these 
35. Terminism is also called as 
(a) Reverse transcription  (b) Transcription 
(c) Translation    (d) Replication 
36. Which of the following inhibits protein synthesis by binding to 50 S ribosome 
(a) Tetracycline    (b) Streptomycin 
(c) Erythromycin   (d) Penicillin 
37. During protein denaturation which of the following is disrupted 
(a) 2D structure    (b) 3D structure 
(c) Peptide bond   (d) AA sequence 
38. Initiation  of polypeptide chain   in  eukaryotic  protein synthesis is induced by 
(a) Methionine (AUG)   (b) Leucine 
(c) Lysine    (d) Glycine 
39. Which of the following sequences will be produced as a result of transcription of the 
DNA sequence CGATTACAG 
(a) GCUAAUGUC   (b) CGUAAUCUG 
(c) GCTAATGTC   (d) GCUAATCTG 
40. Balbiani rings are sites of 
(a) DNA replication 
(b) RNA and protein synthesis 
(c) Synthesis of lipids 
(d) Synthesis of polysaccharides 
41. Actin binding sites are located on 
(a) Troponin 
(b) Tropomyosin 
(c) Meromyosin 
(d) Both tropomyosin and meromyosin 
(e) Both troponin and tropomyosin 
42. Alleles are 
(a) Alternate forms of a gene 
(b) Homologous chromosome 
(c) Pair of sex chromosome 
(d) None of these 
43. The grouping of human chromosomes is based on 
(a) Secondary constrictions alone 
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