Nucleic Acids - PPT, IBT, Biotechnology, Engineering, Semester Biotechnology Engineering (BT) Notes | EduRev

Biotechnology Engineering (BT) : Nucleic Acids - PPT, IBT, Biotechnology, Engineering, Semester Biotechnology Engineering (BT) Notes | EduRev

 Page 1


Chapter 19 (part 1)
Nucleic Acids
Page 2


Chapter 19 (part 1)
Nucleic Acids
Nucleic Acids Are Essential For 
Information Transfer in Cells
• Information encoded in a DNA 
molecule is transcribed via synthesis 
of an RNA molecule 
• The sequence of the RNA molecule 
is "read" and is translated into the 
sequence of amino acids in a 
protein. 
Page 3


Chapter 19 (part 1)
Nucleic Acids
Nucleic Acids Are Essential For 
Information Transfer in Cells
• Information encoded in a DNA 
molecule is transcribed via synthesis 
of an RNA molecule 
• The sequence of the RNA molecule 
is "read" and is translated into the 
sequence of amino acids in a 
protein. 
Central Dogma of Biology
Page 4


Chapter 19 (part 1)
Nucleic Acids
Nucleic Acids Are Essential For 
Information Transfer in Cells
• Information encoded in a DNA 
molecule is transcribed via synthesis 
of an RNA molecule 
• The sequence of the RNA molecule 
is "read" and is translated into the 
sequence of amino acids in a 
protein. 
Central Dogma of Biology
Nucleic Acids
• First discovered in 1869 by Miescher.
• Found as a precipitate that formed when 
extracts from nuclei were treated with 
acid.
• Compound contained C, N, O, and high 
amount of P.
• Was an acid compound found in nuclei 
therefore named nucleic acid
Page 5


Chapter 19 (part 1)
Nucleic Acids
Nucleic Acids Are Essential For 
Information Transfer in Cells
• Information encoded in a DNA 
molecule is transcribed via synthesis 
of an RNA molecule 
• The sequence of the RNA molecule 
is "read" and is translated into the 
sequence of amino acids in a 
protein. 
Central Dogma of Biology
Nucleic Acids
• First discovered in 1869 by Miescher.
• Found as a precipitate that formed when 
extracts from nuclei were treated with 
acid.
• Compound contained C, N, O, and high 
amount of P.
• Was an acid compound found in nuclei 
therefore named nucleic acid
Nucleic Acids
• 1944 Oswald, Avery, MacLeod and 
McCarty demonstrated that DNA is 
the molecule that carrier genetic 
information.
• 1953 Watson and Crick proposed 
the double helix model for the 
structure of DNA
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