Postsynaptic PotentialsLesson 10Postsynaptic Potentials Notes | EduRev

Created by: Gagandeep Singh

: Postsynaptic PotentialsLesson 10Postsynaptic Potentials Notes | EduRev

 Page 1


Postsynaptic 
Potentials
Lesson 10
Page 2


Postsynaptic 
Potentials
Lesson 10
Postsynaptic Potentials
? Signaling in Dendrites & Soma
? V
m
changes
? dendrites & soma
? Excitatory:  +
? Inhibitory:  - ~
Page 3


Postsynaptic 
Potentials
Lesson 10
Postsynaptic Potentials
? Signaling in Dendrites & Soma
? V
m
changes
? dendrites & soma
? Excitatory:  +
? Inhibitory:  - ~
Postsynaptic Potentials - PSPs
? Chemically-gated ion channels
? Graded
? Summation
? Duration
? 10 – 100 milliseconds
? Velocity
? Fast ? approximately speed of light
? Decremental 
? Weaken over time & space  ~
Page 4


Postsynaptic 
Potentials
Lesson 10
Postsynaptic Potentials
? Signaling in Dendrites & Soma
? V
m
changes
? dendrites & soma
? Excitatory:  +
? Inhibitory:  - ~
Postsynaptic Potentials - PSPs
? Chemically-gated ion channels
? Graded
? Summation
? Duration
? 10 – 100 milliseconds
? Velocity
? Fast ? approximately speed of light
? Decremental 
? Weaken over time & space  ~
? Excitatory Postsynaptic Potential
? Depolarization (+)
? V
m
becomes more positive
? Na+ influx ~
EPSPs
Page 5


Postsynaptic 
Potentials
Lesson 10
Postsynaptic Potentials
? Signaling in Dendrites & Soma
? V
m
changes
? dendrites & soma
? Excitatory:  +
? Inhibitory:  - ~
Postsynaptic Potentials - PSPs
? Chemically-gated ion channels
? Graded
? Summation
? Duration
? 10 – 100 milliseconds
? Velocity
? Fast ? approximately speed of light
? Decremental 
? Weaken over time & space  ~
? Excitatory Postsynaptic Potential
? Depolarization (+)
? V
m
becomes more positive
? Na+ influx ~
EPSPs
-55 mV
- 65 mv AT REST
V
m
Time 
EPSP
+
-
? Depolarization
more likely to ? AP ~
Record here
+
Read More
Offer running on EduRev: Apply code STAYHOME200 to get INR 200 off on our premium plan EduRev Infinity!