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Congenital 
Anomalies of Larynx 
Page 2


Congenital 
Anomalies of Larynx 
? The larynx develops from the 
fourth and fifth branchial 
arches. At the third week of 
gestation, the respiratory 
primordium is derived from the 
primitive foregut to later form 
the lung bud and later the 
bronchial bud which will 
eventually develop into the 
tracheobronchial tree.   
? At the fourth and fifth week of 
gestation the tracheo-
oesophageal folds fuse to 
form the tracheo-oesophageal 
septum leading to the 
separation of the tracheal 
airway lumen from the 
esophageal digestive tract.  
Page 3


Congenital 
Anomalies of Larynx 
? The larynx develops from the 
fourth and fifth branchial 
arches. At the third week of 
gestation, the respiratory 
primordium is derived from the 
primitive foregut to later form 
the lung bud and later the 
bronchial bud which will 
eventually develop into the 
tracheobronchial tree.   
? At the fourth and fifth week of 
gestation the tracheo-
oesophageal folds fuse to 
form the tracheo-oesophageal 
septum leading to the 
separation of the tracheal 
airway lumen from the 
esophageal digestive tract.  
Page 4


Congenital 
Anomalies of Larynx 
? The larynx develops from the 
fourth and fifth branchial 
arches. At the third week of 
gestation, the respiratory 
primordium is derived from the 
primitive foregut to later form 
the lung bud and later the 
bronchial bud which will 
eventually develop into the 
tracheobronchial tree.   
? At the fourth and fifth week of 
gestation the tracheo-
oesophageal folds fuse to 
form the tracheo-oesophageal 
septum leading to the 
separation of the tracheal 
airway lumen from the 
esophageal digestive tract.  
Development of Larynx 
? Larynx develops from 
the caudal hypobranchial 
eminence which later 
becomes the epiglottis 
and the cuneiform 
cartilages.  
? Laryngotracheal groove 
is formed at the level of 
the 6th arch and its 
opening is further 
developed to become T 
shaped. On the sides of 
the ‘T’ will be the 
connection of the two 
arytenoids swellings. 
 
Page 5


Congenital 
Anomalies of Larynx 
? The larynx develops from the 
fourth and fifth branchial 
arches. At the third week of 
gestation, the respiratory 
primordium is derived from the 
primitive foregut to later form 
the lung bud and later the 
bronchial bud which will 
eventually develop into the 
tracheobronchial tree.   
? At the fourth and fifth week of 
gestation the tracheo-
oesophageal folds fuse to 
form the tracheo-oesophageal 
septum leading to the 
separation of the tracheal 
airway lumen from the 
esophageal digestive tract.  
Development of Larynx 
? Larynx develops from 
the caudal hypobranchial 
eminence which later 
becomes the epiglottis 
and the cuneiform 
cartilages.  
? Laryngotracheal groove 
is formed at the level of 
the 6th arch and its 
opening is further 
developed to become T 
shaped. On the sides of 
the ‘T’ will be the 
connection of the two 
arytenoids swellings. 
 
? The arytenoid swelling later 
on become the arytenoid 
cartilages. The transverse 
groove forming the 
transverse bar of the T will 
form the ary-epiglottic folds 
and muscles together with 
the corniculate cartilages of 
the larynx. 
? The laryngotracheal groove 
itself forms the respiratory 
tract. Its proximal end forms 
the trachea, the middle forms 
the bronchi while the distal 
forms the lungs. 
 
 
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FAQs on Congenital Anomalies of Larynx Congenital Anomalies of Larynx ? The larynx develops from the

1. What are congenital anomalies of the larynx?
Ans. Congenital anomalies of the larynx are abnormalities in the structure or function of the larynx that are present at birth. These anomalies can affect the vocal cords, cartilage, muscles, or other components of the larynx, leading to a variety of symptoms and potential complications.
2. What causes congenital anomalies of the larynx?
Ans. The exact cause of congenital anomalies of the larynx is often unknown. However, some factors that may contribute to these anomalies include genetic mutations or abnormalities, maternal exposure to certain medications or substances during pregnancy, and disruptions in the normal development of the fetal larynx.
3. What are the common types of congenital anomalies of the larynx?
Ans. Some common types of congenital anomalies of the larynx include vocal cord paralysis, laryngeal web, laryngomalacia, and subglottic stenosis. Vocal cord paralysis refers to the inability of one or both vocal cords to move properly, while a laryngeal web is an abnormal tissue growth that partially blocks the airway. Laryngomalacia is characterized by floppy or weak cartilage in the larynx, and subglottic stenosis is a narrowing of the area below the vocal cords.
4. What are the symptoms of congenital anomalies of the larynx?
Ans. The symptoms of congenital anomalies of the larynx can vary depending on the specific anomaly present. Common symptoms may include hoarseness, difficulty breathing or noisy breathing, stridor (a high-pitched sound during inhalation), recurrent respiratory infections, feeding difficulties, and failure to thrive. In some cases, these anomalies may also cause aspiration or difficulty swallowing.
5. How are congenital anomalies of the larynx diagnosed and treated?
Ans. Congenital anomalies of the larynx are typically diagnosed through a combination of physical examination, medical history review, and imaging tests such as laryngoscopy or CT scan. Treatment options depend on the specific anomaly and its severity. Mild anomalies may not require intervention and may resolve on their own over time. More severe cases may require surgical intervention, such as laryngeal reconstruction or vocal cord surgery, to improve breathing and voice function. Speech therapy and other supportive measures may also be recommended to help manage symptoms and improve quality of life.
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