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Practice Test: Reading Comprehension - 83 | 100 RCs for GMAT PDF Download

Directions: Read the given passage carefully and answer the questions as follows:

Passage

Protein synthesis begins when the gene encoding a protein is activated. The gene’s sequence of nucleotides is transcribed into a molecule of messenger RNA (mRNA), which reproduces the information contained in that sequence. Transported outside the nucleus to the cytoplasm, the mRNA is translated into the protein it encodes by an organelle known as a ribosome, which strings together amino acids in the order specified by the sequence of elements in the mRNA molecule. Since the amount of mRNA in a cell determines the amount of the corresponding protein, factors affecting the abundance of mRNA’s play a major part in the normal functioning of a cell by appropriately regulating protein synthesis. For example, an excess of certain proteins can cause cells to proliferate abnormally and become cancerous; a lack of the protein insulin results in diabetes.

Biologists once assumed that the variable rates at which cells synthesize different mRNA’s determine the quantities of mRNA’s and their corresponding proteins in a cell. However, recent investigations have shown that the concentrations of most mRNA’s correlate best, not with their synthesis rate, but rather with the equally variable rates at which cells degrade the different mRNA’s in their cytoplasm. If a cell degrades both a rapidly and a slowly synthesized mRNA slowly, both mRNA’s will accumulate to high levels.

An important example of this phenomenon is the development of red blood cells from their unspecialized parent cells in bone marrow. For red blood cells to accumulate sufficient concentrations of hemoglobin (which transports oxygen) to carry out their main function, the cells’ parent cells must simultaneously produce more of the constituent proteins of hemoglobin and less of most other proteins. To do this, the parent cells halt synthesis of non-hemoglobin mRNA’s in the nucleus and rapidly degrade copies of the non-hemoglobin mRNA’s remaining in the cytoplasm. Halting synthesis of mRNA alone would not affect the quantities of proteins synthesized by the mRNA’s still existing in the cytoplasm. Biologists now believe that most cells can regulate protein production most efficiently by varying both mRNA synthesis and degradation, as developing red cells do, rather than by just varying one or the other.

Question for Practice Test: Reading Comprehension - 83
Try yourself:According to the passage, which of the following can happen when protein synthesis is not appropriately regulated?
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Question for Practice Test: Reading Comprehension - 83
Try yourself:The accumulation of concentrations of hemoglobin in red blood cells is mentioned in the passage as an example of which of the following?
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Question for Practice Test: Reading Comprehension - 83
Try yourself:The passage is primarily concerned with discussing the
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Question for Practice Test: Reading Comprehension - 83
Try yourself:According to the passage, which of the following best describes the current view on the relationship between the synthesis and the degradation of mRNA in regulating protein synthesis?
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Question for Practice Test: Reading Comprehension - 83
Try yourself:Which of the following best describes the relationship between the second and third paragraphs of the passage?
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Question for Practice Test: Reading Comprehension - 83
Try yourself:The passage suggests that a biologist who detected high levels of two proteins in a certain type of cell would be likely to consider which of the following as a possible explanation?
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Question for Practice Test: Reading Comprehension - 83
Try yourself:The passage suggests that a biologist who held the view described in the first sentence of the second paragraph would most probably also have believed which of the following?
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Question for Practice Test: Reading Comprehension - 83
Try yourself:To begin to control a disease caused by a protein deficiency, the passage suggests that a promising experimental treatment would be to administer a drug that would reduce
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