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Mnemonics: Inflammation

Cardinal Signs of Inflammation

What needs to be memorized: The 5 classic signs of inflammation: Rubor (Redness), Calor (Heat), Tumor (Swelling), Dolor (Pain), Functio laesa (Loss of function)

Mnemonic: "Ram's Car Tyre Definitely Failed"

🔗 The Breakdown:

  • Ram's → Rubor (Redness)
  • Car → Calor (Heat)
  • Tyre → Tumor (Swelling)
  • Definitely → Dolor (Pain)
  • Failed → Functio laesa (Loss of function)

Steps of Leukocyte Extravasation (Migration)

What needs to be memorized: The sequential steps WBCs take to leave blood vessels: Margination, Rolling, Adhesion, Transmigration, Chemotaxis

Mnemonic: "My Rickshaw Always Takes Chai-breaks"

🔗 The Breakdown:

  • My → Margination
  • Rickshaw → Rolling
  • Always → Adhesion
  • Takes → Transmigration
  • Chai-breaks → Chemotaxis

Cell-Derived Chemical Mediators of Inflammation

What needs to be memorized: Major cell-derived mediators: Histamine, Serotonin, Prostaglandins, Leukotrienes, Platelet Activating Factor (PAF), Cytokines, Nitric Oxide

Mnemonic: "Hot Samosas Please! Later Paneer Curry Needed"

🔗 The Breakdown:

  • Hot → Histamine
  • Samosas → Serotonin
  • Please → Prostaglandins
  • Later → Leukotrienes
  • Paneer → PAF (Platelet Activating Factor)
  • Curry → Cytokines
  • Needed → Nitric Oxide

Cells in Chronic Inflammation

What needs to be memorized: Main cells present in chronic inflammation: Macrophages, Lymphocytes, Plasma cells, Eosinophils, Fibroblasts

Mnemonic: "Mummy's Lunch Paratha's Extra Filling"

🔗 The Breakdown:

  • Mummy's → Macrophages
  • Lunch → Lymphocytes
  • Paratha's → Plasma cells
  • Extra → Eosinophils
  • Filling → Fibroblasts

Causes of Caseating Granulomas

What needs to be memorized: Main causes of caseating granulomas: Tuberculosis, Leprosy, Fungal infections

Mnemonic: "Tiffin Left Friday"

🔗 The Breakdown:

  • Tiffin → Tuberculosis
  • Left → Leprosy
  • Friday → Fungal infections

Causes of Non-Caseating Granulomas

What needs to be memorized: Main causes: Sarcoidosis, Crohn's disease, Berylliosis, Cat scratch disease, Foreign body

Mnemonic: "Sachin's Cricket Bat Continuously Fabulous"

🔗 The Breakdown:

  • Sachin's → Sarcoidosis
  • Cricket → Crohn's disease
  • Bat → Berylliosis
  • Continuously → Cat scratch disease
  • Fabulous → Foreign body

Types of Inflammatory Exudates

What needs to be memorized: Four main types: Serous, Fibrinous, Purulent (Suppurative), Hemorrhagic

Mnemonic: "Students Frequently Postpone Homework"

🔗 The Breakdown:

  • Students → Serous
  • Frequently → Fibrinous
  • Postpone → Purulent
  • Homework → Hemorrhagic

Outcomes of Acute Inflammation

What needs to be memorized: Four possible outcomes: Resolution, Repair/Fibrosis, Chronic inflammation, Abscess formation

Mnemonic: "Results Regularly Create Anxiety"

🔗 The Breakdown:

  • Results → Resolution
  • Regularly → Repair/Fibrosis
  • Create → Chronic inflammation
  • Anxiety → Abscess formation

Sequential Vascular Changes in Acute Inflammation

What needs to be memorized: The sequence: Transient vasoconstriction → Vasodilation → Increased permeability → Stasis

Mnemonic: "Traffic Vehicles Initially Stop"

🔗 The Breakdown:

  • Traffic → Transient vasoconstriction
  • Vehicles → Vasodilation
  • Initially → Increased permeability
  • Stop → Stasis

Positive Acute Phase Reactants

What needs to be memorized: Proteins that increase in inflammation: CRP, Serum Amyloid A (SAA), Fibrinogen, Ferritin, Hepcidin, Complement

Mnemonic: "Cricket Score Finally Favours Home Captain"

🔗 The Breakdown:

  • Cricket → CRP (C-Reactive Protein)
  • Score → SAA (Serum Amyloid A)
  • Finally → Fibrinogen
  • Favours → Ferritin
  • Home → Hepcidin
  • Captain → Complement

Arachidonic Acid Metabolic Pathways

What needs to be memorized: COX pathway produces Prostaglandins & Thromboxane; LOX pathway produces Leukotrienes, Lipoxins & HETE

Mnemonic: "COX pathway = 'PT class' | LOX pathway = 'LLH group'"

🔗 The Breakdown:

  • COX pathway (PT class):
    • PProstaglandins
    • TThromboxane
  • LOX pathway (LLH group):
    • LLeukotrienes
    • LLipoxins
    • HHETE

💡 Tip: "PT class" reminds you of Physical Training class - easy to remember!

Complement Activation Pathways

What needs to be memorized: Three pathways of complement activation: Classical, Alternative, Lectin (MBL pathway)

Mnemonic: "Chai Aur Lassi"

🔗 The Breakdown:

  • Chai → Classical pathway
  • Aur → Alternative pathway
  • Lassi → Lectin pathway (MBL)

Lysosomal Enzymes in Inflammation

What needs to be memorized: Important lysosomal enzymes: Acid proteases, Elastase, Collagenase, Cathepsins

Mnemonic: "Aunty's Elder Children Cry"

🔗 The Breakdown:

  • Aunty's → Acid proteases
  • Elder → Elastase
  • Children → Collagenase
  • Cry → Cathepsins

Systemic Effects of Inflammation

What needs to be memorized: Constitutional symptoms: Fever, Leukocytosis, Increased heart rate, Anorexia, Somnolence

Mnemonic: "Flu Leaves Indians Always Sleepy"

🔗 The Breakdown:

  • Flu → Fever
  • Leaves → Leukocytosis
  • Indians → Increased heart rate
  • Always → Anorexia
  • Sleepy → Somnolence
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