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Homeostasis:

A human being is shaped by millions of cells that are working together for the maintenance of all organs in a human body. All cells require quite the similar metabolism but they perform different functions. For the well-being for the entire human organism, every individual cell needs to maintain the internal environment like glucose, oxygen, mineral ions and waste removal.

The process that a body maintains internally is collectively called as homeostasis. The concept of homeostasis was first described in 1865 by a French Physiologist named Claude Bernard, but the word was first used in 1926 by Walter Bradford Cannon.

 

Homeostasis | Biology for SSS 3

 

What is Homeostasis?

Homeostasis is a property of a human biological system where the self-regulating process tends to maintain the balance for the survival. The regulation takes place in a defined internal environment. For example, the regulation of body temperature, glucose in blood plasma, extracellular fluids of an animal changes despite what the animal has eaten or what it is doing. Every variable is controlled by homeostasis together to maintain life.

In simple terms, it could be referred as a balance in a system to maintain a stable internal environment for the survival of the animal. If the homeostasis regulates successfully, life continues or if unsuccessful, death or disaster occurs.

The regulation by homeostasis consist of three mechanisms:

  1. Receptor
  2. Control Center
  3. Effector

Receptor: The receptor acts as a receiver. It receives the changes in the environment.

Control Center: The Control Center is also known as integration center. It receives all the information that the receptor has collected from the changes in the environment.

Effector: As the name suggests, it responds to the commands of the control center. It could either oppose or change the stimulus.

The entire process continuously works to maintain the homeostasis regulation. For instance, the regulation of body temperature, there are receptors in the skin, that communicates information to the brain, which acts as the control center and the blood vessels (effector) and sweat glands in our skin maintain the temperature.

Examples of physiological homeostasis:

  1. Arterial blood pressure homeostat.
  2. Blood glucose homeostat.
  3. Blood oxygen content homeostat.
  4. Blood partial pressure of oxygen and carbon dioxide homeostasis
  5. Core body temperature homeostat.
  6. Extracellular fluid pH homeostat.
  7. Extracellular potassium concentration homeostat.
  8. Extracellular sodium concentration homeostat.
  9. Plasma ionized calcium homeostat.
  10. Volume of body water homeostat.

Homeostasis Breakdown:

The failure of homeostasis function in an internal environment will result in many diseases. A functional component of homeostasis can malfunction due to an inherited defect or by affected disease. Few homeostasis has the capability of inbuilt redundancy, ensuring safer life even if a homeostasis component malfunctions. However, in other cases, a malfunction in any component of homeostasis leads to severe disease or death.

Body Systems and Homeostasis:

The body system participates in maintaining homeostasis regulations. The function of body system describes various regulatory mechanisms where every system is contributed to homeostasis. Here are few tables that describe the function of every organs homeostasis.

Formed Elements
NameFunction
PlateletsIt assist blood clotting
Red blood cellsHelps to transport hydrogen and oxygen ions
White blood cellsIt fights against infection

 

Plasma
ComponentFunction
NutrientsRequired for cellular metabolism
ProteinsCreate osmotic pressure, aid clotting, and help buffer blood
HormonesKnown as chemical messengers
WaterProvides fluid environment
SaltsAid metabolic activity and help buffer blood
Wastes

Produced by cellular metabolism

 

Nervous System
Central Nervous System
CerebrumConsciousness, creativity, thought, morals, memory
Lower portionsReception of sensory data, coordination of muscular activity, homeostasis
Spinal cordAutomatic reflex actions
Peripheral Nervous System
Autonomic systemThose cranial and spinal motor nerves that control internal organs
Cranial nerves, spinal nervesCarry sensory information to motor impulses from the CNS

 

Major Endocrine Glands and Their Major Hormones
NameHormoneFunction
Adrenal cortexGlucocorticoids (e.g., cortisol)Promotes gluconeogenesis
Mineralocorticoids (e.g., aldosterone)Promotes sodium reabsorption by kidneys
Adrenal medullaEpinephrine and norepinephrineStimulates fight or flight reaction
Anterior pituitaryThyroid-stimulatingStimulates thyroid
AdrenocorticotropicStimulates adrenal cortex
GonadotropicStimulates gonads
GonadsAndrogens (male) Estrogens and progesterone (female)Promotes secondary sex characteristics
HypothalamusHypothalamic-releasing and release-inhibiting hormonesRegulate anterior pituitary hormones
Posterior pituitaryAntidiureticPromotes water reabsorption by kidney
ParathyroidParathyroidMaintains blood calcium and phosphorus levels
ThyroidThyroxinIncreases metabolic rate
PancreasInsulinLowers blood sugar level
GlucagonRaises blood sugar level
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FAQs on Homeostasis - Biology for SSS 3

1. What is homeostasis?
Ans. Homeostasis is the body's ability to maintain a stable and balanced internal environment despite external changes. It involves various physiological processes that help regulate body temperature, blood sugar levels, pH balance, and other vital functions.
2. How does homeostasis work?
Ans. Homeostasis works through a negative feedback mechanism. When the body senses a deviation from the set point, such as an increase in temperature, it activates mechanisms to reverse the change and bring it back to the normal range. For example, sweating and vasodilation help cool down the body when it becomes too hot.
3. What are examples of homeostasis in the human body?
Ans. Examples of homeostasis in the human body include the regulation of body temperature, blood pressure, blood sugar levels, pH balance, and water balance. These mechanisms ensure that the body's internal environment remains stable and optimal for proper functioning.
4. How does the body regulate blood sugar levels?
Ans. The body regulates blood sugar levels through the action of insulin and glucagon, both hormones produced by the pancreas. When blood sugar levels rise after a meal, insulin is released to facilitate the uptake of glucose by cells, thus lowering blood sugar levels. Conversely, when blood sugar levels drop, glucagon is released to stimulate the breakdown of glycogen into glucose, increasing blood sugar levels.
5. What happens if homeostasis is disrupted?
Ans. If homeostasis is disrupted, it can lead to various health problems. For example, if body temperature regulation fails, hyperthermia or hypothermia can occur. Imbalances in blood sugar levels can result in conditions like diabetes. Disruptions in pH balance can lead to acid-base imbalances. Therefore, maintaining homeostasis is crucial for overall health and well-being.
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