A: RNA polymerase is of three types in eukaryotes for the synthesis of all types of RNAs.
R: RNA polymerase consists of six types of polypeptides along with rho factor, which is involved in the termination of RNA synthesis.
A: 5S rRNA and the surrounding protein complex provides the binding site of tRNA.
R: tRNA is soluble RNA with unusual bases.
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A: Operator gene is functional when a repressor does not block it.
R: Regulator gene produces active protein only, which acts on the operon system in E.coli.
A: Peptidyl transfer site is contributed by a larger subunit of ribosome.
R: Both 23S and 16S ribosomal sub-units contribute the enzyme peptidyl transferase.
A: Teminism is the unidirectional flow of information.
R: It requires DNA dependent RNA polymerase enzyme.
A: In the bacterial translation mechanism, two tRNA are required by methionine.
R: AUG codes for methionine, and it shows non-ambiguity also.
A: Nutritional mutant strain of pink mould is auxotroph.
R: It is not able to prepare its own metabolites from the raw materials obtained from outside.
A: In DNA fingerprinting, hybridization is done with the molecular probe.
R: Molecular probe is a small DNA segment synthesized in a laboratory with a known sequence that recognises the complementary sequence in RNA.
A: c-DNA libraries are important to scientists in human genomics.
R: c-DNA is a synthetic type of DNA generated from mRNA.
A: SNPs-pronounced "snips" are common in the human genome.
R: It is minute variations that occur at a frequency of one in every 300 bases.
A: Catalytic functions were assigned to RNA molecule during evolution.
R: The rate of mutation is quite fast in RNA.
A: Kornberg enzyme is associated with the removal of primers and thymine dimer.
R: DNA polymerase I does exonuclease activity in 5’→3’ and 3’→5’ directions.
A: Wobbling reduces the number of tRNAs required for polypeptide synthesis.
R: It increases the effect of code degeneracy.
A: Unknown DNA after hybridization with VNTR probe, the autoradiogram gives many bands of differing sizes in DNA profiling.
R: These bands represent the DNA fingerprint of an organism.
A: Polypeptide sequences are dictated by DNA and represented by mRNA.
R: Sequence of amino acids in a polypeptide can be predicted by the exact sequence of nucleotides on the mRNA and template DNA.
A: Triplet genetic code can be confirmed by frameshift mutations.
R: Frame shifting involves the change in protein product coded by triplet codons.
A: Lac operon exerts negative control only.
R: The operator is occupied by aporepressor during regulation.
A: Single DNA dependent RNA polymerase catalyses the transcription of all types of RNA in all except bacteria.
R: Structural genes in bacteria are monocistronic.
A: Sigma factor of RNA polymesase recognizes the start signal region in prokaryotes.
R: Promotor region lies at 5¢ of the template strand.
A: HGP was completed in 2003 by sequencing all genes of all chromosomes.
R: All coding and noncoding genes were sequenced by ESTs.