Biomacromolecules (NCERT) - Free MCQ Practice Test with solutions, NEET

Lipids, though they do not have high molecular weights like other macromolecules, are part of the acid insoluble fraction because they arrange into structures like cell membranes. When tissues are ground up, these membranes break into vesicles that are not water-soluble, leading to their categorization as part of the acid insoluble fraction despite their smaller size.

Topic in NCERT: Biomolecules

Line in NCERT: "therefore, these membrane fragments in the form of vesicles get separated along with the acid insoluble pool and hence in the macromolecular fraction."

The acid soluble pool within cells primarily represents the cytoplasmic composition, comprising various small molecules that play roles in cellular metabolism and function. This includes metabolites, ions, and other small biomolecules that are crucial for cellular processes.

Topic in NCERT: Biomolecules

Line in NCERT: "the acid soluble pool represents roughly the cytoplasmic composition."

Proteins constitute a significant portion of the cellular mass, making up about 10-15% of it. This makes them vital for numerous cellular functions, including acting as enzymes, structural components, and signaling molecules.

Topic in NCERT: Proteins

Line in NCERT: "proteins\n% of the total\ncellular mass\n10-15"

The acid soluble pool is characterized by having lower molecular weight compounds ranging from 18 to around 800 daltons and typically includes water and small ions, matching with Option B in Column II. The acid insoluble fraction includes macromolecules such as proteins, nucleic acids, and polysaccharides, which generally have molecular weights above ten thousand daltons, aligning with Option A in Column II. Thus, the correct match is 1-B, 2-A.

Topic in NCERT: Nature of enzyme action

Line in NCERT: Error occcured while getting response from embedding

The assertion is true as lipids, though typically having molecular weights not exceeding 800 Da, are found in the acid insoluble fraction. The reason correctly explains this by stating that lipids are involved in forming cell membrane structures that are not water-soluble. When tissues are disrupted, these membrane structures break into vesicles that end up in the macromolecular fraction due to their insolubility in water. Thus, Reason R provides the correct explanation for Assertion A.