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Principles of Inheritance & Variation - 2 - Free MCQ Practice Test


MCQ Practice Test & Solutions: Test: Principles of Inheritance & Variation - 2 (20 Questions)

You can prepare effectively for NEET Biology Class 12 with this dedicated MCQ Practice Test (available with solutions) on the important topic of "Test: Principles of Inheritance & Variation - 2". These 20 questions have been designed by the experts with the latest curriculum of NEET 2026, to help you master the concept.

Test Highlights:

  • - Format: Multiple Choice Questions (MCQ)
  • - Duration: 20 minutes
  • - Number of Questions: 20

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Test: Principles of Inheritance & Variation - 2 - Question 1

Dihybrid cross proves the law of _________.

Detailed Solution: Question 1

  • In a dihybrid cross, two new kinds of plants with new traits are formed. This is possible only when all traits assort independently and recombine to form a new combination.
  • Mendel found that each pair of alleles segregates independently of the other pairs of alleles during gamete formation. 
  • This is known as the Law of independent assortment and hence it can be proved by the dihybrid cross.

Explain the law of independent assortment with a suitable class 12 biology CBSE

Hence, the correct option is C

Topic in NCERT: Law of Independent Assortment

Line in NCERT: "Based upon such observations on dihybrid crosses (crosses between plants differing in two traits) Mendel proposed a second set of generalisations that we call Mendel's Law of Independent Assortment."

Test: Principles of Inheritance & Variation - 2 - Question 2

In pea plants, yellow seeds are dominant to green, If a heterozygous yellow seeded plant is crossed with a green seeded plant, what ratio of yellow and green seeded plants would you expect in F1 generation?

Detailed Solution: Question 2

  • Since the yellow seeds are dominant to green, the allele for yellow seeds should be represented with upper case letter while the one for green seeds should be written in lower case letter.
  • Let's suppose that the allele for yellow seed is Y and that for green seeds is y. Hence the genotype of the heterozygous yellow seeded plant will be "Yy" and that for green seeded plant will be "yy" (as the recessive allele is expressed only in homozygous conditions).
  • The cross between heterozygous yellow seeded plant and green seeded plant will produce 50% yellow seeded plants and 50% green seeded plants.

Hence, the correct option is C
In pea, yellow seed colour is dominant over green colour. Heterozygous yellow seeded plant is crossed with green seeded plant. The ratio of yellow to green seeded offspring will be ______.9 : 11 : 33 : 150 : 50.

Test: Principles of Inheritance & Variation - 2 - Question 3

In a cross between a pure tall plant with green pod and a pure short plant with yellow pod. How many short plants are produced in F2 generation out of 16?  

Detailed Solution: Question 3

  • Genotype of pure tall plant with green pod = TTGG
  • Genotype of pure dwarf plant with yellow pod = ttgg
  • P generation:  TTGG    X  ttgg
  • F1 generation: TtGg (tall plant, green pod)

Selfing: TtGg X  TtGg

As can be seen from the table, a total 4 short plants with genotypes ttGG, ttGg, ttGg and ttgg are produced.

Hence, the correct option is B

Topic in NCERT: Mendelian Genetics

Line in NCERT: "1/4th of the random fertilisations lead to TT, 1/2 lead to Tt and 1/4th to tt."

Test: Principles of Inheritance & Variation - 2 - Question 4

The test cross is used to determine the  ________.

Detailed Solution: Question 4

In a test cross:

  • The organism with the dominant trait is always crossed with an organism with the recessive trait. 
  • If any offspring show the recessive trait, the unknown genotype is heterozygous
  • If all the offspring have the dominant trait, the unknown genotype is homozygous dominant.

Fig: The test cross

Hence, the correct option is A

Topic in NCERT: Test Cross

Line in NCERT: "Therefore, to determine the genotype of a tall plant at F, Mendel crossed the tall plant from F2 with a dwarf plant. This he called a test cross."

Test: Principles of Inheritance & Variation - 2 - Question 5

The genotypes of a husband and wife are IIB and IAi. Among the blood types of their children how many different genotypes and phenotypes are possible?

Detailed Solution: Question 5

A cross between two individuals, one with AB blood group and the other with A blood group will produce four genotypes and three phenotypes.

The genotypes of a husband and wife are IAIB and IAi.
Four different possible genotypes of their children are: IAIB, IAi, IBi, IAIA

The possible number of phenotypes of their children are:

  • Blood group A (IAIA, IAi)
  • Blood group B (IBi)
  • Blood group AB (IAIB)

Fig: Cross between blood groups AB and A 
Hence, the correct option is B.
NCERT Reference: Topic  Co-dominance” of chapter "Principles of Inheritance and Variation"  of NCERT 

Topic in NCERT: ABO Blood Group Genetics

Line in NCERT: "Since there are three different alleles, there are six different combinations of these three alleles that are possible, and therefore, a total of six different genotypes of the human ABO blood types."

Test: Principles of Inheritance & Variation - 2 - Question 6

Which of the following is an example of co-dominance?

Detailed Solution: Question 6

  • Co-dominance is the phenomenon that deviates from Mendel’s law of inheritance.
  • Both the alleles appear in offspring instead of one as in Mendel’s experiment.
  • ABO blood grouping in human beings is an example of co-dominance in which both IA and IB appear simultaneously to form AB blood type.

Hence, the correct option is D.

Topic in NCERT: Co-dominance

Line in NCERT: "A good example is different types of red blood cells that determine ABO blood grouping in human beings."

Test: Principles of Inheritance & Variation - 2 - Question 7

A human male produces sperms with the genotypes AB, Ab, aB, ab pertaining to two diallelic characters in equal proportions. What is the corresponding genotype of this person?

Detailed Solution: Question 7

  • If the genotype is AaBb the alleles that are produced will be AB, Ab, aB, ab, since there are two diallelic characters in the genotypes the person must be heterozygous for both genes. AABB is homozygous. So, the correct answer is "AaBb".

Fig: Diallelic characters in the genotype

Hence, the correct option is B.

NCERT Reference: Topic - INHERITANCE OF TWO GENES” of chapter "Principles of Inheritance and Variation"  of NCERT 

Test: Principles of Inheritance & Variation - 2 - Question 8

In Mirabilis jalapa, when two F1 pink flowered plants were crossed with each other, the F2 generation produced 40 red, 80 pink and 40 white flowering plants. This a case of:

Detailed Solution: Question 8

  • F1 pink flowered plants are heterozygous. When selfing is done the genotype and phenotype develops as 1:2:1 as 40 red, 80 pink and 40 white flowering plants.  It is called Incomplete dominance.
  • The appearance of a new phenotype in the progeny but not either of the parents is called Incomplete dominance.

Fig: Cross showing incomplete dominance in Mirabilis jalapa

Hence, the correct option is C.
NCERT Reference: Topic-  Incomplete Dominance” of chapter "Principles of Inheritance and Variation" of NCERT.

Topic in NCERT: Incomplete Dominance

Line in NCERT: "When the F, was self-pollinated the F2 resulted in the following ratio 1 (RR) Red: 2 (Rr) Pink: 1 (rr) White."

Test: Principles of Inheritance & Variation - 2 - Question 9

Assertion: The cross between red and white flower-bearing snapdragon plants results in pink coloured flower.
Reason: Incomplete dominance of red and white flower results in pink coloured flowers.

Detailed Solution: Question 9

  • In Snapdragon flower, cross between true-breeding white and red coloured flower produce pink coloured flower in the F1 generation.
  • This happens due to the incomplete dominance of alleles over the other.

Hence, the correct option is A.
NCERT Reference: Topic -  Incomplete Dominance of chapter "Principles of Inheritance and Variation" of NCERT.

Topic in NCERT: Incomplete Dominance

Line in NCERT: "The inheritance of flower colour in the dog flower (snapdragon or Antirrhinum sp.) is a good example to understand incomplete dominance. In a cross between true-breeding red-flowered (RR) and true-breeding white-flowered plants (rr), the F1 (Rr) was pink."

Test: Principles of Inheritance & Variation - 2 - Question 10

When two genes are situated very close to one another on a chromosome _________.

Detailed Solution: Question 10

  • When two genes are situated very close to one another on the chromosome, hardly any cross-over is produced.
  • Such genes are called linkage and do not separate from each other during gamete formation.

Hence, the correct option is A.

Topic in NCERT: Linkage and Recombination

Line in NCERT: "some genes were very tightly linked (showed very low recombination)"

Test: Principles of Inheritance & Variation - 2 - Question 11

Statement I: The bridge between one generation and the next is sperm and ovum.
Statement II: Both sperm and ovum contribute equally to heredity.
Statement III: Somatic diploid cells possess two sets of chromosomes, one set inherited from each parent, and two alleles (Mendelian factors) for each gene, one on each homologous chromosome.

Detailed Solution: Question 11

Statement I: The bridge between one generation and the next is sperm and ovum.

  • This is correct. Sperm and ovum are the gametes that combine during fertilization to form a zygote, which then develops into a new individual, thereby bridging generations.

Statement II: Both sperm and ovum contribute equally to heredity.

  • This is generally correct, but with a slight clarification. While both sperm and ovum contribute genetic material (DNA), they do so in equal amounts (each contributing one set of chromosomes), meaning the genetic contribution is equal in terms of number of chromosomes. However, the ovum provides the majority of the cytoplasm and organelles, while the sperm provides the genetic material. So, strictly speaking, they contribute equally in terms of the genetic information, but not necessarily in all aspects of heredity.

Statement iii : Somatic diploid cells possess two sets of chromosomes, one set inherited from each parent, and two alleles (Mendelian factors) for each gene, one on each homologous chromosome.

  • Somatic diploid cells: These are cells with two complete sets of chromosomes (diploid), one from each parent.
  • Two sets of chromosomes: This emphasizes that somatic cells have pairs of chromosomes (in humans, 23 pairs).
  • Two alleles for each gene: This clarifies that each gene has two alleles, one on each of the homologous chromosomes.

Test: Principles of Inheritance & Variation - 2 - Question 12

How can a female be haemophilic?

Detailed Solution: Question 12

This sex linked recessive disease, which shows its transmission from unaffected carrier female to some of the male progeny has been widely studied. In this disease, a single protein that is a part of the cascade of proteins involved in the clotting of blood is affected. Due to this, in an affected individual a simple cut will result in non-stop bleeding. The heterozygous female (carrier) for haemophilia may transmit the disease to sons.The possibility of a female becoming a haemophilic is extremely rare because mother of such a female has to be at least carrier and the father should be haemophilic (unviable in the later stage of life). If Mother is normal and father is haemophilic then daughter will be carrier not haemophilic.

Hence, the correct option is D.

NCERT Reference: Topic “Haemophilia” of chapter  "Principles of Inheritance and Variation" of NCERT.

Topic in NCERT: Haemophilia

Line in NCERT: "The possibility of a female becoming a haemophilic is extremely rare because mother of such a female has to be at least carrier and the father should be haemophilic."

Test: Principles of Inheritance & Variation - 2 - Question 13

A colour blind girl is rare because she will be born only when 

Detailed Solution: Question 13

  • The father of a colour blind female must be colour blind.
  • The mother has to be at least a carrier. This is possible if the maternal grandfather was colour blind [remember criss-cross].

Hence, the correct option is B.

NCERT Reference: Topic- Colour Blindness of chapter "Principles of Inheritance and Variation" of NCERT.

Test: Principles of Inheritance & Variation - 2 - Question 14

Which of the following is a recessive trait for a character chosen by Mendel in garden pea?

Detailed Solution: Question 14

  • Yellow pod colour of the pea plant is a recessive trait.
  • Mendel studied seven contrasting traits in pea (Pisum sativum), which are as follows:


Hence, the correct option is B.

Topic in NCERT: Contrasting Traits Studied by Mendel in Pea

Line in NCERT: "Contrasting Traits\nS.No.\nCharacters\n1.\nStem height\nTall/dwarf\n2.\nFlower colour\nViolet/white\n3.\nFlower position\n4.\nPod shape\n5.\nPod colour\n6.\nSeed shape\nAxial/terminal\nInflated/constricted\nGreen/yellow\nRound/wrinkled\n7.\nSeed colour\nYellow/green"

Test: Principles of Inheritance & Variation - 2 - Question 15

Identify the incorrect statement:

Detailed Solution: Question 15

  • Both tall and dwarf plants produce gametes by mitosis.
  • Plants use meiosis only to produce spores that develop into multicellular haploid gametophytes which produce gametes by mitosis.

Therefore, gamete formation in both tall and dwarf plants is by mitosis.

Hence, the correct option is A.
Note: This question is based on basic understanding of inheritance of genes.

Topic in NCERT: Segregation of Alleles

Line in NCERT: "only one allele is transmitted to a gamete."

Test: Principles of Inheritance & Variation - 2 - Question 16

The ultimate source of allelic variation is:

Detailed Solution: Question 16

  • Gene is a segment of DNA and new alleles arise by mutation - a sudden inheritable change in DNA. Mutations can alter single nucleotides or entire chromosomes.
  • The ultimate source of genetic variation is random mutation i.e. changes in nucleotide sequences of DNA. They may involve only a single base pair or many as in chromosomal mutations.
  • Change in the allele frequency and introduction of new alleles are the basis of genetic variation occurring in any population.

Fig: Showing Mutation 

Hence, the correct option is C.
NCERT Reference: Topic- MUTATION” of chapter  "Principles of Inheritance and Variation" of NCERT.

Topic in NCERT: MUTATION

Line in NCERT: "Such an alteration or change in the genetic material is referred to as mutation."

Test: Principles of Inheritance & Variation - 2 - Question 17

In the inheritance of flower color in the dog flower (snapdragon or Antirrhinum sp.), what is observed when a true-breeding red-flowered (RR) plant is crossed with a true-breeding white-flowered (rr) plant?

Detailed Solution: Question 17

In the scenario where a true-breeding red-flowered (RR) plant is crossed with a true-breeding white-flowered (rr) plant in the dog flower species, the resulting F1 offspring displays a pink flower color. This outcome is a classic example of incomplete dominance, where neither of the parental traits dominates completely, leading to an intermediate phenotype in the offspring. This phenomenon is crucial in understanding genetic inheritance patterns beyond simple dominant and recessive relationships.

Topic in NCERT: Incomplete Dominance

Line in NCERT: "The F1 (Rr) was pink."

Test: Principles of Inheritance & Variation - 2 - Question 18

In the context of co-dominance, what happens when both the IA and IB alleles are present in an individual?

Detailed Solution: Question 18

In the scenario of co-dominance where both IA and IB alleles are present, they express their own types of sugars simultaneously. This occurrence is due to the unique nature of co-dominance, where neither allele suppresses the other, resulting in the expression of both sugar types. This leads to red blood cells displaying both A and B types of sugars, showcasing a co-dominant inheritance pattern.

Topic in NCERT: Co-dominance

Line in NCERT: "But when I A and B are present together they both express their own types of sugars: this is because of co-dominance."

Test: Principles of Inheritance & Variation - 2 - Question 19

How does the Law of Segregation explain the inheritance of traits in offspring?

Detailed Solution: Question 19

The Law of Segregation clarifies that alleles segregate independently during gamete formation, ensuring that each gamete receives only one of the two factors or alleles from a parent. This segregation process underlies the inheritance of traits and explains why both parental traits are not always visible in the F1 generation. Heterozygous parents, which carry two different alleles for a trait, produce gametes with equal proportions of each allele, contributing to genetic diversity in offspring.

Topic in NCERT: Law of Segregation

Line in NCERT: "Though the parents contain two alleles during gamete formation, the factors or alleles of a pair segregate from each other such that a gamete receives only one of the two factors."

Test: Principles of Inheritance & Variation - 2 - Question 20

What type of inheritance pattern does thalassemia follow?

Detailed Solution: Question 20

Thalassemia follows an autosomal recessive inheritance pattern, meaning that two copies of the mutated gene are necessary for the disease to manifest.

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