Chemistry Exam > Chemistry Videos > Organic Chemistry > Baeyer Villiger Oxidation
Baeyer Villiger Oxidation Video Lecture | Organic Chemistry
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FAQs on Baeyer Villiger Oxidation Video Lecture - Organic Chemistry
| 1. What is Baeyer Villiger Oxidation? |  |
Ans. Baeyer Villiger Oxidation is a chemical reaction in which a ketone or an aldehyde is converted into an ester or a lactone, respectively, by using a peracid as an oxidizing agent.
| 2. How does Baeyer Villiger Oxidation occur? | |
Ans. Baeyer Villiger Oxidation occurs through the nucleophilic attack of a peracid on the carbonyl group of a ketone or an aldehyde. This attack leads to the formation of a tetrahedral intermediate, which then rearranges to yield the desired ester or lactone product.
| 3. What are the applications of Baeyer Villiger Oxidation? | |
Ans. Baeyer Villiger Oxidation finds widespread applications in organic synthesis. It is often used to introduce an oxygen atom into a molecule, which can be useful in the synthesis of various pharmaceuticals, natural products, and fine chemicals.
| 4. What are the limitations of Baeyer Villiger Oxidation? | |
Ans. Baeyer Villiger Oxidation can sometimes be limited by the availability of suitable peracids. Additionally, certain functional groups, such as strong electron-withdrawing groups, can hinder the reaction. The reaction may also exhibit selectivity issues, leading to the formation of undesired byproducts.
| 5. Are there any alternative methods to Baeyer Villiger Oxidation? | |
Ans. Yes, there are alternative methods to achieve similar transformations. Some of these include using other oxidizing agents such as m-CPBA (meta-chloroperoxybenzoic acid), catalytic systems, or enzymatic approaches. These alternative methods may offer different selectivity or functional group compatibility.
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Nov 22, 2024 Last updated |
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