Grignard reagent (Part 1) - Organic Chemsitry Video Lecture - Class 11

gray not pleased gray not recent missile
or economical come for organic compounds
are those the most in which carbon is
directly attached with the metal gets
reference between metal organic
economically metal known organic and
organo metallic then come on organ attic
as I told you where carbon is directly
attached net metal but madam ugly is all
make energy but the scholar is attached
with some non metal such as oxygen
sulfur and this electronegative atom is
not as depth matter such a compound is
called as metal oak or may come for
example example of alpha metric is ch3
align ch3 and z vr cs3 twice see you
align cs3 twice seven here coverage
directly attached with metal Carla is
directing a times width matter so this
type of compound is called as ornamental
but cs300 a ch3 as ening ch3coo easy it
is si in which component of a condition
where an oxygen sulphur oxygen is
directly attached with matter
so these type of hormones are
metal or nickel or very hot is very
mechanism is commonly called as our MZ x
that is Carmen is directing a test with
metal so it is an example of or no metal
come home and ice as I told you Gilligan
on occasion is our MZ x so first
vibrations here Jia means bring up
things we can prepare green odd reason
just like taking alkali it's against
with magnesium
so when Alki high is created with
magnesium entire ether as a solvent then
our MZ x is for necklace.this this is
our X this is magnesium lone pair of air
tones of hello soon a half over
magnesium and this electone of magnesium
and over carbon and that's this book and
finally our MZ x will be opening so
increase of preparation of zr al-qaida
height is driven with magnesium in ether
drinker and on jaques is obtained this
is subscribe this is reason
this is solvent and this one is the
product this Ziya may act as a reason
for some other chemical reaction this
substrate has to bar that is alcohol and
haricot first we consider a problem
arise out of a guy or a this are maybe
single warning this are maybe double
bonded this are even maybe take a wonder
this are maybe already this are maybe
aliphatic case I think this are maybe
heterocyclic this are maybe heterocyclic
anointing this are maybe / reset
aldehyde nowadays we can take any type
of our of alkali but one thing is clear
this are do not have a cell hydrogen or
Parcel Post
Karla where this negative on me attack
so important what is this this are maybe
single bonded never wanted triple wanted
an emetic aliphatic ill cyclic had no
cyclic anything but it does not have a
cell hydrogen or Parcel Post a center
that is
ah maybe single bonded or maybe single
bonded double bonded triple wanted
aromatic
any cyclic heterocyclic they said it is
anything but he wanted what is this this
R does not have acetic hydrogen a
partial positive Center ah does not have
a sonic hydrogen or partial positive
Center now come to the other part this
Felson maybe I mean maybe going maybe
Chloe or maybe throwing this are then
attached to i BR CL on F but very
carefully analyzed I are we are our seal
and hive
then F is placed here then you will
access definitely difference between
these spots
yep on top goes that side so yo graphic
Center and basic electro decreases so in
normal cases flowing is not used for the
preparation of Xia
so normally al-qaida iodine join and a
kind collects are used for the
preparation of our mg acts so we can use
iodine blowing employee in
but generally flowing is away now as
required magnesium in objects so this
magnesium must be present we can change
the solvent meter the solvent Ethan may
be acyclic may be cyclic may be polyter
well as I click on a cyclic it will not
be a box ID or four-member cyclic ether
it is important this organ should not be
free never cyclic ether or for we were
segregated because three member and four
membered cyclic ether have strain the
angle is 60 degree and here angle is 90
degree so carbon is sp3 carbon is sp3
but anti is 16 someone could have
industry and you to angle screen
discover municipal service users and Zr
is a good nucleophile may attack over
this carbon and crack this boom so
further chemical reaction may decrease
so these two eaters are over yet but we
can use five membered cyclic ether we
can use a cyclic ethers we can also use
poly ether so normal n equals I used by
elimination is three member and four
member cycling little so now the
question is can you use any other medium
other than eater in one part is very
observe the basic behind
rmgx here rmgx the Alki bar or objects
is electron rich so it will will very
good baits and it will also be a very
good nucleophile so whenever there is
partial positive Center partial forcing
center this are we act as a nucleophile
to attack over the spot so any height
kilo ohms
astral a CLI mmm and hydrate our tripod
of objects is a very good nucleophile so
it may attack the more partial forces
until this angle may be a carbonyl yes
until value of al-qaeda right listen to
them waving of M oxide so we can now see
we cannot use acetone and solvent
because as you do not have partial
positive charge over the garden so this
gr can attack over this carbon and make
the elbow suffer mechanical action take
place with a ketone so we cannot use
ketone as a solvent for the preparation
of Zr now this Alki part of RDX is also
very good base so it can attack Oh
this is a hydrogen this is the basic
part is the same part so it is also a
good base so it can easily attack over
the proton so we cannot use water
because water is like Adelson this ways
may attack over this Adelson we cannot
use alcohol because hydrogen is again
acetic this year is always attack over
hydrocele we cannot use any way shifts
because this hydrogen is again as living
a chip
so a funny part is this we can only use
dry ether for the preparation of three
nod reason because ethers are chemically
unreactive towards in a nucleophile or
base forgive addictions this we cannot
use three membered and four membered
cyclic leaves certain eaters now combine
a chemical reaction is also please a
double root it also act as a stabilizing
phenomena this is our o our this is
again our own ah the lower oxygen gift
upon density towards magnesium
completing is obtained so ether also act
as a stabilizing medium for CR whether
this will not listen is stable along
with maybe providing video for this
calculation now come to the emulation
as I told you our MZ x this R is very
good base and also this R is very good
nucleophile this is the basic of getting
our division so any molecule which have
as any chiral sin anymore you'll the
chaff acetic I do sir
this is Yong will attack and give our H
as the program but they're more you have
passive warships under further CR act as
a nucleophile so in these off
le hides ketone and hydrate esters in an
easy derive act as a dip your file in
case of alkali in case of a box I will
remember when a four-member it can
attack assumed name your file so
calculation may be a Sydney's
calculation may be nucleophilic if y1 is
broken hydrogen attached so calculation
may be nucleophilic addition if
nucleophile attack over this for hello
zone is replaced so a very nucleophilic
substitution so we will care one by one
what are the reactions of green are
using first a sea bass H
this is our MZ x on training event water
on train Madrid elbow on treatment with
terminal alkynes on take method just
twist on Raymond with our such on trade
word with fin all on a quintet
carboxylic acid whether aliphatic or
anodic trading with with any chicks take
one with
Delta boonie comments take with it
Pender DYI this our will act as a base
attacks all this hydrogen and finally
form our H as a product and respawn
attach this to give MZ x + H similarly
if we consider these part as V so
remaining part is MZ x + V so this this
is the cycler and this is the way to
another say what is our when Z our
attack with acetic hydrogen this phone
is broken and I drew some is attacks
with alcohol this all as I told you may
be Saints in the water
maybe down ponder maybe take your own
net so chemical ation you'll be asked
like this find the product of
pollination unzips water
this may be lightness orange it's at sea
maybe like this Isaac's water so there's
a acetic hydrogen this is about bass can
easily attack above this to give
this type of work so one type of a
change is a race where hydrogen is
attached to the alcohol now second is
the organization organization as I call
you al Qaeda book of our Jets is a copy
of your file so first substitution entry
when Al Qaeda high is created with rmgx
this mainly aah
this may be hard are destined GX this is
a particular file can attack over this
carbon and leaves a solution as a living
will and final product will be on our
ass as it is a choreography so nation of
nation we be will be sn2 question very
house like this ch3cl
ch3 ch2 and z VL really ch3 ch2 ch3 MZ
be our nucleophile attack over this
carbon lace the seal give pervane and
some product here again nucleophile
attack over this carbon resolution to
give no pain again as a product but
pushing will be if this is r1 and this
is r2 which chemical reaction is having
faster rate so important part goes to
let's ascent you
we can look about the Stipe factor over
the alpha life not the nucleophile this
carbon has passed
oh she chose less steric hindrance so
yes they will fight easily attack over
this carbon and it is healthy but this
carbon has more steric factor so
nucleophilic attack over this carbon is
respectable so rate of r1 is positive as
compared to order say chemical reaction
may be asked on the lysis of sn2
mechanism that is fine the reactivity
find the lead of the calculation for the
reputation of one type of product
calculation laney from any height or
Tito's this R is a particular file can
use easily attack over this carbonyl
carbon breakfast norm for burning a cave
or h1r every drop this particular
molecule into another container which
are acidic hydrogen suggests water
so this nebula file-based attack of a
proton to give final alcohol as a
product so here my wants are broken
corresponding to u sigma boats are for
so this is erection of addition so
addition product is form after the
election of grignard reagent over the
happy to similarly a said I am I right
after this
rmgx will attack Rex this one similar to
the Gambino's on owning it in acts Oh
cor or here this carbon has two air
colligative atom PI bond is formed and
this lemon goes boo boo so ketone or
aldehyde this maybe catch or are this
may be edge on are so very high or
ketones are form creativity of a VIP
rose a higher as
he said away and hide right off a strip
because of additional conjugation with
the lone pair of oxygen ions on with the
co lo for a activity of any IQ knows a
higher as compared to a satellite and
hydrated ester so another Zr which is
present in the ocean can even attack
over the spot and give during active on
our h and r sm ah there's finally take
protons from William from other actions
and dinner and finally secondary or
testing and what is okay if this column
is gas with hydrogen then secondary role
will be obtained and if this carbon is
there too attached to carbon until C L
will be obtained as long present so
important what is this Ziya attack with
radii key tone to give alcohol Ziya also
attachment attack with etc and hydrate
ester to give alcohol but here when one
of CR is used in a chemical reaction but
in this case two molecules
Asya are used in a calculation to give
final algo and s own
now
right right f CR / nitelite this is our
MZ x this carbon also have our suppose
she chose so this gr may attack over
discarded brats this I want to give our
see our number one and negative MZ v r+
again when what we said just like a
divorce
abstract prolong to give our see our
double bond nn H
I mean this carbon has faucet position
turn so water will act as a nucleophile
and heck of a discarded let's this pi
bond to give RC r and h o h h- chars
this nitrogen abstract form to give AA
on H and NS to the basic after reducing
is higher as compared to oxygen so
nettles are accepted on this platform
was in this side and ammonia gas is
released and finally the product will be
kilo so Zia attacks over nitrites to
give keto as a trigger a 1 and what is
this this is own will not react with
others here to give Alvarez a product as
I told you he said arrive and I die or
ester because this is a container in
which
Zr is they we added our seein this
raishin container a chemical reaction
occur in this pot now this particular
molecule has water we add this part in
the list and now this reaction this
reaction is started out in this time at
this chamber not in the silver so no
another CR will attack over this part
because this container do not have any
CR molecule so final product is the
cocoon not the algorithm so this is the
best method for the provision of ADUN
from CR that is when ZRX over the
carbonyl carbon ketone will be of T now
hmph epoxy
this is a boss I remember cycling eater
this is r and z ax Alki part of this
orange X is electron rich
electronegativity difference these two
car would have pasta pasta sauce but as
I told you