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Factors Affecting Bioactivity - Physiological Video Lecture | CSIR NET Crash Course for Chemical Science - CSIR NET Chemical Science
FAQs on Factors Affecting Bioactivity - Physiological Video Lecture - CSIR NET Crash Course for Chemical Science - CSIR NET Chemical Science
| 1. What are some of the key factors that can affect the bioactivity of a molecule? |  |
Ans. Some key factors that can affect the bioactivity of a molecule include its chemical structure, solubility, stability, target receptor interactions, and metabolic transformation within the body.
| 2. How does the physiological environment influence the bioactivity of a compound? | |
Ans. The physiological environment, such as pH levels, presence of enzymes, and other molecules in the body, can significantly impact the bioactivity of a compound by affecting its stability, absorption, distribution, metabolism, and excretion.
| 3. Can the route of administration affect the bioactivity of a molecule? | |
Ans. Yes, the route of administration can influence the bioactivity of a molecule. For example, a molecule may have different bioavailability and potency when administered orally compared to when administered intravenously.
| 4. What role does the molecular weight of a compound play in its bioactivity? | |
Ans. The molecular weight of a compound can affect its bioactivity by influencing its ability to cross biological membranes, interact with target receptors, and be metabolized within the body. Generally, smaller molecules tend to have higher bioavailability and potency.
| 5. How can understanding the factors affecting bioactivity help in the design of more effective drugs? | |
Ans. Understanding the factors affecting bioactivity can help in the rational design of drugs with optimized pharmacokinetic and pharmacodynamic properties. By considering factors such as chemical structure, solubility, stability, and target interactions, researchers can develop drugs that are more potent, selective, and safe.
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Nov 22, 2024 Last updated |
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