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All questions of Gastroenterology for PLAB/UKMLA Exam
All of the following is true regarding G.E.R.D except? (JIPMER Nov 2014)- a)Occurs during transient relaxation of L.E S
- b)Can present with nocturnal cough
- c)Bicarbonate secreted by esophageal mucosa neutralizes the acid
- d)Normal esophageal mucosa on endoscopy excludes G.E.R.D
Correct answer is option 'C'. Can you explain this answer?
All of the following is true regarding G.E.R.D except? (JIPMER Nov 2014)
a)
Occurs during transient relaxation of L.E S
b)
Can present with nocturnal cough
c)
Bicarbonate secreted by esophageal mucosa neutralizes the acid
d)
Normal esophageal mucosa on endoscopy excludes G.E.R.D
 | Dr. Ritesh Malhotra answered |
- Mechanisms of GERD:
- Transient LES relaxations
- LES hypotension
- Anatomic distortion of the esophagogastric junction inclusive of hiatus hernia
- The acid can reflux can lead to chemical tracheitis leading to nocturnal cough and bronchospasm.
- GERD is often diagnosed in the absence of endoscopic esophagitis, which would otherwise define the disease. In setting of partially treated disease ambulatory 24 hours pH monitoring is done and the outcome is expressed as the percentage of the day that the pH was less than 4 (indicative of recent acid reflux), with values exceeding 5% indicative of GERD.
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