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GATE Biotechnology Mock Test - 4 - GATE Biotechnology MCQ


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30 Questions MCQ Test - GATE Biotechnology Mock Test - 4

GATE Biotechnology Mock Test - 4 for GATE Biotechnology 2025 is part of GATE Biotechnology preparation. The GATE Biotechnology Mock Test - 4 questions and answers have been prepared according to the GATE Biotechnology exam syllabus.The GATE Biotechnology Mock Test - 4 MCQs are made for GATE Biotechnology 2025 Exam. Find important definitions, questions, notes, meanings, examples, exercises, MCQs and online tests for GATE Biotechnology Mock Test - 4 below.
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GATE Biotechnology Mock Test - 4 - Question 1
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Examine the subsequent statements:
(i) Every individual in the class is ready for the examination.
(ii) Babu extended an invitation to Danish at his residence because he takes pleasure in playing chess.
What is the ACCURATE observation regarding the two sentences mentioned above?

GATE Biotechnology Mock Test - 4 - Question 2
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_____ relates to surgery in the same way that a writer relates to ________
Which of the following options preserves a corresponding logical relationship in the statement above?

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GATE Biotechnology Mock Test - 4 - Question 3
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Secret is to Furtive as Audible is to __________.

Detailed Solution for GATE Biotechnology Mock Test - 4 - Question 3

Furtive is more intensely secret, and resonant is more intensely audible.

GATE Biotechnology Mock Test - 4 - Question 4
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Which number should follow in this sequence?

6, 10, 7, 11, 8, 12, ?
Detailed Solution for GATE Biotechnology Mock Test - 4 - Question 4

This is a simple alternating addition and subtraction series. In the first pattern, 4 is added and in the second, 3 is subtracted.
Pattern is:
6 + 4 = 10,
10 - 3 = 7,
7 + 4 = 11,
11 - 3 = 8,
8 + 4 = 12,
12 - 3 = 9.

GATE Biotechnology Mock Test - 4 - Question 5
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Analyze the subsequent two statements and select the correct option.

Assertion (A): The differential equation (ey - 4) sin x dx - ey cos x dy = 0 is not an exact equation.
Reason (R): The differential equation Mdx Ndy = 0 is considered exact if

Detailed Solution for GATE Biotechnology Mock Test - 4 - Question 5

We have (ey - 4) sin x dx - ey cos x dy = 0
Here M = (ey - 4) sin x and N = - ey cos x

The differential equation is exact. Thus, A is false, but R is true.

GATE Biotechnology Mock Test - 4 - Question 6
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Which amino acid listed below does not engage in transamination during the process of catabolism?
Detailed Solution for GATE Biotechnology Mock Test - 4 - Question 6

Transamination involves the movement of α-amino group from donor amino acid to the acceptor α-keto acid. Three amino acids: lysine, proline and threonine do not participate in this process.

GATE Biotechnology Mock Test - 4 - Question 7
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Valinomycin acts as a mobile ion carrier and is utilized as an antibiotic. Which organism(s) is/are the source of this antibiotic?
Detailed Solution for GATE Biotechnology Mock Test - 4 - Question 7

Many microbial species produce antibiotics, which are toxic to certain other microbial species. For example, valinomycin is produced by Streptomyces fulvissimus. It functions as a potassium-specific transporter and facilitates the movement of potassium ions through lipid membranes "down" the electrochemical potential gradient.

GATE Biotechnology Mock Test - 4 - Question 8
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Which of the following serves as the primary location for the detoxification of xenobiotics within a cell?
Detailed Solution for GATE Biotechnology Mock Test - 4 - Question 8

SER in hepatic cells are the major sites for removal of xenobiotics. Cytochrome P-450 present in the SER catalyses this reaction.

GATE Biotechnology Mock Test - 4 - Question 9
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In which of the following microbial species is extrachromosomal plasmid DNA not present?
Detailed Solution for GATE Biotechnology Mock Test - 4 - Question 9

E. coli K - 12 is a bacterial strain, which does not contain plasmid (though it can be transformed). E.coli is a ''lab strain'' and the most commonly used strain in transformation experiments.

GATE Biotechnology Mock Test - 4 - Question 10
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The diagram depicting the process and instrumentation for a feedback control system designed to sustain the liquid level (h) in a tank by controlling a valve (V) is illustrated below. F1 represents the inflow rate of the liquid, F2 indicates the outflow rate, LT stands for the liquid level transmitter, LC is the liquid level controller, hsp denotes the desired liquid level setpoint, hm is the actual liquid level measurement, and PV signifies the pressure of the valve.

The variable(s) being manipulated is/are
GATE Biotechnology Mock Test - 4 - Question 11
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A circular plasmid, which was closed, underwent cleavage by the restriction endonuclease EcoRI, resulting in two fragments of equal length. How many EcoRI restriction sites are present on the plasmid?
Detailed Solution for GATE Biotechnology Mock Test - 4 - Question 11

Cleavage of a circular plasmid can yield two fragments only if the endonuclease has two restriction sites on the plasmid.

GATE Biotechnology Mock Test - 4 - Question 12
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Which of the following options is/are utilized for bioremediation?
Detailed Solution for GATE Biotechnology Mock Test - 4 - Question 12

Bioremediation is a process used to treat contaminated media, including water, soil and subsurface material, by altering environmental conditions to stimulate growth of microorganisms and degrade the target pollutants. Aerobic, anaerobic bacteria and ligninolytic fungi can be used for this purpose.

GATE Biotechnology Mock Test - 4 - Question 13
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Which of the following statements most accurately describes the characteristics of interleukin 1 (IL-1)?
Detailed Solution for GATE Biotechnology Mock Test - 4 - Question 13

Interleukin 1 is a protein produced by macrophages that has three biologically active forms: IL-,  and . Its functions include activation of B cells and stimulation of helper and cytotoxic T cells. Its activity is not histocompatibility restrained.

*Answer can only contain numeric values
GATE Biotechnology Mock Test - 4 - Question 14
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The DNA obtained from the cells of a specific species underwent biochemical analysis to determine its sequence. It was observed that the content of A (adenine) in the DNA is approximately 30%. Calculate the percentage of G (guanine) present.
(Give your answer in percentage)

Detailed Solution for GATE Biotechnology Mock Test - 4 - Question 14

According to the Chargaff's rule, the molar ratio of A to T (or G to C) equals 1, i.e. the amount of A in a dsDNA is equal to that of T.
Thus,
Amount of T in the DNA = 30%
The total content of A + T = 30 + 30 = 60%
Therefore, the remaining 40% DNA would be constituted by G and C.
Since, G = C, G = C = 40/2 = 20% each
or, the content of G in DNA = 20%

GATE Biotechnology Mock Test - 4 - Question 15
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If , then which of the following statements holds true?
Detailed Solution for GATE Biotechnology Mock Test - 4 - Question 15

Let the value of f(x) be y.

Or, f-1(x) =  = f(x) for all the values of x.

GATE Biotechnology Mock Test - 4 - Question 16
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A peptide was cleaved into two smaller peptides through the action of cyanogen bromide (CNBr) and into two distinct fragments by trypsin (Trp). The sequences obtained were as follows:

Identify the sequence of the original parent peptide.
Detailed Solution for GATE Biotechnology Mock Test - 4 - Question 16

Cyanogen bromide hydrolyzes peptide bonds at the C-terminus of methionine residues.Trypsin cleaves peptide chains mainly at the carboxyl side of the amino acids lysine or arginine.
By arranging the sequences in an overlapping set, it is possible to determine the parent sequence:

GATE Biotechnology Mock Test - 4 - Question 17
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Which of the following tools is utilized to analyze all potential six-open reading frames of a specific nucleotide query sequence against all existing six-open reading frames in the nucleotide sequence database?
GATE Biotechnology Mock Test - 4 - Question 18
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A significant category of pumps powered by ATP are the ABC-type ATPases, commonly referred to as ABC transporters. The catalytic domains of these proteins bind ATP during the transport process.

Which of the following statements is/are incorrect?

A. ATPases were first identified in prokaryotic organisms, but an increasing number have also been found in eukaryotic organisms.

B. They form a vast superfamily of transport proteins that share similarities in both sequence and molecular mechanism.

C. They possess only two ATP-binding domains and lack integral domains.

D. In contrast to most ABC transporters, MDR exhibits a notably broad specificity, enabling it to export a diverse array of chemically distinct drugs from cells.
Detailed Solution for GATE Biotechnology Mock Test - 4 - Question 18

The typical ABC-type ATPase has four domains, two of which are highly hydrophobic while the other two are peripherally located on the cytosolic side of the membrane. Each of the two embedded domains has six transmembrane segments that form a structure through which solutes pass. The two peripheral domains are actually the cassettes that bind ATP and couple ATP hydrolysis to the intracellular transport. In some cases, these four domains are a part of a large multifunctional polypeptide.

GATE Biotechnology Mock Test - 4 - Question 19
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The modification of proteins after translation occurs within the ER and Golgi apparatus.
I. The formation of disulphide bonds in the lumen of the ER is aided by the enzyme Protein Disulphide Isomerase (PDI).
II. Proteins synthesized on free ribosomes in the cytoplasm and organelles do not contain disulphide bonds.

Assess the most suitable relationship between the two statements provided.
Detailed Solution for GATE Biotechnology Mock Test - 4 - Question 19

The cytosol has a reducing environment which maintains cysteine residues in their reduced state and disulphide bonds are not formed. Hence, cytoplasmic proteins and organelle proteins synthesized on free ribosome lack disulphide bonds. The disulphide bonds in secretory proteins are synthesized in the ER lumen facilitated by enzyme Protein Disulphide Isomerase (PDI).

GATE Biotechnology Mock Test - 4 - Question 20
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Which of the following assertions regarding E. coli are accurate?

P. E. coli is classified as a gram-negative, non-spore forming prokaryote.

Q. It has the ability to undergo natural transformation with foreign genes, making it a valuable tool in recombinant DNA technology.

R. Its genome was the first to be sequenced among prokaryotes.

S. Certain strains of E. coli can cause disease in humans.
Detailed Solution for GATE Biotechnology Mock Test - 4 - Question 20

E. coli is a gram-negative, non-spore forming prokaryote and some of the strains are pathogenic to humans. Though it is used as a microbial model in genetics experiments, it cannot be naturally transformed. It is transformed by first making it competent for taking up foreign genes. Its genome was the first prokaryotic genome to be sequenced.

GATE Biotechnology Mock Test - 4 - Question 21
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Which of the following statements is true for both archaebacteria and eubacteria?

P. The cell wall of archaebacteria includes muramic acid, whereas the cell wall of eubacteria consists of peptidoglycan lacking muramic acid.
Q. The cell wall of archaebacteria does not have muramic acid, while eubacteria's cell wall contains peptidoglycan with muramic acid.
R. Archaebacteria show no sensitivity to chloramphenicol, in contrast to eubacteria, which do exhibit sensitivity to chloramphenicol.
S. Archaebacteria are sensitive to chloramphenicol, whereas eubacteria are not.
Detailed Solution for GATE Biotechnology Mock Test - 4 - Question 21

Archaebacteria are primitive bacteria that are usually found in extreme environments. They differ highly from eubacteria in their cell structure and functions, e.g. they don't have muramic acid in their cell walls while eubacteria do. Similarly, archae are insensitive to chloramphenicol but eubacteria are sensitive to it.

*Answer can only contain numeric values
GATE Biotechnology Mock Test - 4 - Question 22
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Given the values of two random variables (X, Y) as (121, 360), (242, 364), and (363, 362), what is the correlation coefficient between X and Y when rounded to one decimal place?

*Answer can only contain numeric values
GATE Biotechnology Mock Test - 4 - Question 23
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What is the determinant of the matrix


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GATE Biotechnology Mock Test - 4 - Question 24
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Evaluate the integral given below:

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GATE Biotechnology Mock Test - 4 - Question 25
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The probability distribution for a random variable X is displayed below:

Given that E(X) = 2.3, determine the value of k.
(Provide your answer rounded to the nearest integer)

Detailed Solution for GATE Biotechnology Mock Test - 4 - Question 25




⇒ k = 2

*Answer can only contain numeric values
GATE Biotechnology Mock Test - 4 - Question 26
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If the helix pitch (H; the distance along the axis for a complete 360-degree rotation) of a DNA molecule is 33.2 Å and the helix rise per base pair (Δp) is 3.32 Å, calculate the number of turns in the molecule assuming it contains 5000 base pairs.

Detailed Solution for GATE Biotechnology Mock Test - 4 - Question 26

No. of bp per turn, n = H/Δp
n = 33.2/3.32 = 10
No. of bp in the DNA molecule = 5000
No. of turns in the molecule, N = 5000/10
N = 500 turns

*Answer can only contain numeric values
GATE Biotechnology Mock Test - 4 - Question 27
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A feed stream ( F1 ) that includes components A and B is treated within a system featuring a separation unit and a mixer, as depicted in the schematic diagram below. The mole fractions of components A and B are represented as xA and xB, respectively. Given that
F1 F2 = 100 kg h−1, the degrees of freedom of the system is ________.

*Answer can only contain numeric values
GATE Biotechnology Mock Test - 4 - Question 28
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Calculate the number of peptide units present in an enzyme, given that its molecular weight was measured to be 160,000 and 40,000 using gel filtration and SDS-PAGE respectively. (Provide your answer as a single-digit whole number.)

Detailed Solution for GATE Biotechnology Mock Test - 4 - Question 28

The detergent SDS causes the dissociation of quaternary structures and allows the determination of molecular weight of the component subunits. The given data suggests that the enzyme comprises four identical subunits of molecular weight 40,000 each yielding a tetramer of 160,000.

*Answer can only contain numeric values
GATE Biotechnology Mock Test - 4 - Question 29
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Instructions: Each amino acid in a protein is represented by a distinct triplet nucleotide sequence in mRNA, referred to as a codon. This means that for every 3 nucleotide base pairs in the gene, there corresponds one amino acid in the resulting protein.

What would be the estimated molecular weight of the duplex DNA required to produce a protein with a molecular weight of 40,000?

Detailed Solution for GATE Biotechnology Mock Test - 4 - Question 29

Average molecular weight of an amino acid residue = 110
Therefore, the no. of amino acids in the protein = 40,000/110 ~ 364
Since, three bp are required to code for one amino acid,
Hence, minimum no. of bp in DNA = 3 × 364 = 1090
Average weight of one bp = 650
Hence, molecular weight of 1090 bp = 650 × 1090 = 7,08,500

*Answer can only contain numeric values
GATE Biotechnology Mock Test - 4 - Question 30
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Milk is being heated from 10o C to 85o C as it flows through a stainless steel inner tube with an inner diameter of 40 mm in a double tube-type heater. The process utilizes saturated steam that condenses at 120o C on the outer surface of the inner tube. The total heat transferred (Q) is 146200 Kcal h-1, and the overall heat transfer coefficient is 750 kcal h-1 m-2o C-1. What is the total length of the heating tube in meters (rounded to one decimal place)?

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