Test: Practice Test - 4 - Class 10 MCQ

Question is based on the following passage.

This passage is adapted from MacDonald Harris, The Balloonist. ©2011 by The Estate of Donald Heiney. During the summer of 1897, the narrator of this story, afictional Swedish scientist, has set out for the North Pole in a hydrogen powered balloon.

My emotions are complicated and not
readily verifiable. I feel a vast yearning that is
simultaneously a pleasure and a pain. I am certain
of the consummation of this yearning, but I don’t
5 know yet what form it will take, since I do not
understand quite what it is that the yearning desires.
For the first time there is borne in upon me the full
truth of what I myself said to the doctor only an hour
ago: that my motives in this undertaking are not
10 entirely clear. For years, for a lifetime, the machinery
of my destiny has worked in secret to prepare for this
moment; its clockwork has moved exactly toward
this time and place and no other. Rising slowly from
the earth that bore me and gave me sustenance, I am
15 carried helplessly toward an uninhabited and hostile,
or at best indifferent, part of the earth, littered with
the bones of explorers and the wrecks of ships, frozen
supply caches, messages scrawled with chilled fingers
and hidden in cairns that no eye will ever see.
20 Nobody has succeeded in this thing, and many have
died. Yet in freely willing this enterprise, in choosing
this moment and no other when the south wind
will carry me exactly northward at a velocity of
eight knots, I have converted the machinery of my
25 fate into the servant of my will. All this I understand,
as I understand each detail of the technique by which
this is carried out. What I don’t understand is why I
am so intent on going to this particular place. Who
wants the North Pole! What good is it! Can you eat
30 it? Will it carry you from Gothenburg to Malmö like
a railway? The Danish ministers have declared from
their pulpits that participation in polar expeditions is
beneficial to the soul’s eternal well-being, or so I read
in a newspaper. It isn’t clear how this doctrine is to
35 be interpreted, except that the Pole is something
difficult or impossible to attain which must
nevertheless be sought for, because man is
condemned to seek out and know everything
whether or not the knowledge gives him pleasure. In
40 short, it is the same unthinking lust for knowledge
that drove our First Parents out of the garden.
And suppose you were to find it in spite of all, this
wonderful place that everybody is so anxious to stand
on! What would you find? Exactly nothing.
45 A point precisely identical to all the others in a
completely featureless wasteland stretching around it
for hundreds of miles. It is an abstraction, a
mathematical fiction. No one but a Swedish madman
could take the slightest interest in it. Here I am. The
50 wind is still from the south, bearing us steadily
northward at the speed of a trotting dog. Behind us,
perhaps forever, lie the Cities of Men with their
teacups and their brass bedsteads. I am going forth of
my own volition to join the ghosts of Bering and
55 poor Franklin, of frozen De Long and his men.
What I am on the brink of knowing, I now see, is not
an ephemeral mathematical spot but myself. The
doctor was right, even though I dislike him.
Fundamentally I am a dangerous madman, and what
60 I do is both a challenge to my egotism and a
surrender to it.

Q. The sentence in lines 10-13 (“For years... other”) mainly serves to

Question is based on the following passage.

This passage is adapted from MacDonald Harris, The Balloonist. ©2011 by The Estate of Donald Heiney. During the summer of 1897, the narrator of this story, afictional Swedish scientist, has set out for the North Pole in a hydrogen powered balloon.

My emotions are complicated and not
readily verifiable. I feel a vast yearning that is
simultaneously a pleasure and a pain. I am certain
of the consummation of this yearning, but I don’t
5 know yet what form it will take, since I do not
understand quite what it is that the yearning desires.
For the first time there is borne in upon me the full
truth of what I myself said to the doctor only an hour
ago: that my motives in this undertaking are not
10 entirely clear. For years, for a lifetime, the machinery
of my destiny has worked in secret to prepare for this
moment; its clockwork has moved exactly toward
this time and place and no other. Rising slowly from
the earth that bore me and gave me sustenance, I am
15 carried helplessly toward an uninhabited and hostile,
or at best indifferent, part of the earth, littered with
the bones of explorers and the wrecks of ships, frozen
supply caches, messages scrawled with chilled fingers
and hidden in cairns that no eye will ever see.
20 Nobody has succeeded in this thing, and many have
died. Yet in freely willing this enterprise, in choosing
this moment and no other when the south wind
will carry me exactly northward at a velocity of
eight knots, I have converted the machinery of my
25 fate into the servant of my will. All this I understand,
as I understand each detail of the technique by which
this is carried out. What I don’t understand is why I
am so intent on going to this particular place. Who
wants the North Pole! What good is it! Can you eat
30 it? Will it carry you from Gothenburg to Malmö like
a railway? The Danish ministers have declared from
their pulpits that participation in polar expeditions is
beneficial to the soul’s eternal well-being, or so I read
in a newspaper. It isn’t clear how this doctrine is to
35 be interpreted, except that the Pole is something
difficult or impossible to attain which must
nevertheless be sought for, because man is
condemned to seek out and know everything
whether or not the knowledge gives him pleasure. In
40 short, it is the same unthinking lust for knowledge
that drove our First Parents out of the garden.
And suppose you were to find it in spite of all, this
wonderful place that everybody is so anxious to stand
on! What would you find? Exactly nothing.
45 A point precisely identical to all the others in a
completely featureless wasteland stretching around it
for hundreds of miles. It is an abstraction, a
mathematical fiction. No one but a Swedish madman
could take the slightest interest in it. Here I am. The
50 wind is still from the south, bearing us steadily
northward at the speed of a trotting dog. Behind us,
perhaps forever, lie the Cities of Men with their
teacups and their brass bedsteads. I am going forth of
my own volition to join the ghosts of Bering and
55 poor Franklin, of frozen De Long and his men.
What I am on the brink of knowing, I now see, is not
an ephemeral mathematical spot but myself. The
doctor was right, even though I dislike him.
Fundamentally I am a dangerous madman, and what
60 I do is both a challenge to my egotism and a
surrender to it.

Q. The narrator indicates that many previous explorers seeking the North Pole have

Question is based on the following passage.

This passage is adapted from MacDonald Harris, The Balloonist. ©2011 by The Estate of Donald Heiney. During the summer of 1897, the narrator of this story, afictional Swedish scientist, has set out for the North Pole in a hydrogen powered balloon.

My emotions are complicated and not
readily verifiable. I feel a vast yearning that is
simultaneously a pleasure and a pain. I am certain
of the consummation of this yearning, but I don’t
5 know yet what form it will take, since I do not
understand quite what it is that the yearning desires.
For the first time there is borne in upon me the full
truth of what I myself said to the doctor only an hour
ago: that my motives in this undertaking are not
10 entirely clear. For years, for a lifetime, the machinery
of my destiny has worked in secret to prepare for this
moment; its clockwork has moved exactly toward
this time and place and no other. Rising slowly from
the earth that bore me and gave me sustenance, I am
15 carried helplessly toward an uninhabited and hostile,
or at best indifferent, part of the earth, littered with
the bones of explorers and the wrecks of ships, frozen
supply caches, messages scrawled with chilled fingers
and hidden in cairns that no eye will ever see.
20 Nobody has succeeded in this thing, and many have
died. Yet in freely willing this enterprise, in choosing
this moment and no other when the south wind
will carry me exactly northward at a velocity of
eight knots, I have converted the machinery of my
25 fate into the servant of my will. All this I understand,
as I understand each detail of the technique by which
this is carried out. What I don’t understand is why I
am so intent on going to this particular place. Who
wants the North Pole! What good is it! Can you eat
30 it? Will it carry you from Gothenburg to Malmö like
a railway? The Danish ministers have declared from
their pulpits that participation in polar expeditions is
beneficial to the soul’s eternal well-being, or so I read
in a newspaper. It isn’t clear how this doctrine is to
35 be interpreted, except that the Pole is something
difficult or impossible to attain which must
nevertheless be sought for, because man is
condemned to seek out and know everything
whether or not the knowledge gives him pleasure. In
40 short, it is the same unthinking lust for knowledge
that drove our First Parents out of the garden.
And suppose you were to find it in spite of all, this
wonderful place that everybody is so anxious to stand
on! What would you find? Exactly nothing.
45 A point precisely identical to all the others in a
completely featureless wasteland stretching around it
for hundreds of miles. It is an abstraction, a
mathematical fiction. No one but a Swedish madman
could take the slightest interest in it. Here I am. The
50 wind is still from the south, bearing us steadily
northward at the speed of a trotting dog. Behind us,
perhaps forever, lie the Cities of Men with their
teacups and their brass bedsteads. I am going forth of
my own volition to join the ghosts of Bering and
55 poor Franklin, of frozen De Long and his men.
What I am on the brink of knowing, I now see, is not
an ephemeral mathematical spot but myself. The
doctor was right, even though I dislike him.
Fundamentally I am a dangerous madman, and what
60 I do is both a challenge to my egotism and a
surrender to it.

Q. Which choice provides the best evidence for the answer to the previous question?

Question is based on the following passage.

This passage is adapted from MacDonald Harris, The Balloonist. ©2011 by The Estate of Donald Heiney. During the summer of 1897, the narrator of this story, afictional Swedish scientist, has set out for the North Pole in a hydrogen powered balloon.

My emotions are complicated and not
readily verifiable. I feel a vast yearning that is
simultaneously a pleasure and a pain. I am certain
of the consummation of this yearning, but I don’t
5 know yet what form it will take, since I do not
understand quite what it is that the yearning desires.
For the first time there is borne in upon me the full
truth of what I myself said to the doctor only an hour
ago: that my motives in this undertaking are not
10 entirely clear. For years, for a lifetime, the machinery
of my destiny has worked in secret to prepare for this
moment; its clockwork has moved exactly toward
this time and place and no other. Rising slowly from
the earth that bore me and gave me sustenance, I am
15 carried helplessly toward an uninhabited and hostile,
or at best indifferent, part of the earth, littered with
the bones of explorers and the wrecks of ships, frozen
supply caches, messages scrawled with chilled fingers
and hidden in cairns that no eye will ever see.
20 Nobody has succeeded in this thing, and many have
died. Yet in freely willing this enterprise, in choosing
this moment and no other when the south wind
will carry me exactly northward at a velocity of
eight knots, I have converted the machinery of my
25 fate into the servant of my will. All this I understand,
as I understand each detail of the technique by which
this is carried out. What I don’t understand is why I
am so intent on going to this particular place. Who
wants the North Pole! What good is it! Can you eat
30 it? Will it carry you from Gothenburg to Malmö like
a railway? The Danish ministers have declared from
their pulpits that participation in polar expeditions is
beneficial to the soul’s eternal well-being, or so I read
in a newspaper. It isn’t clear how this doctrine is to
35 be interpreted, except that the Pole is something
difficult or impossible to attain which must
nevertheless be sought for, because man is
condemned to seek out and know everything
whether or not the knowledge gives him pleasure. In
40 short, it is the same unthinking lust for knowledge
that drove our First Parents out of the garden.
And suppose you were to find it in spite of all, this
wonderful place that everybody is so anxious to stand
on! What would you find? Exactly nothing.
45 A point precisely identical to all the others in a
completely featureless wasteland stretching around it
for hundreds of miles. It is an abstraction, a
mathematical fiction. No one but a Swedish madman
could take the slightest interest in it. Here I am. The
50 wind is still from the south, bearing us steadily
northward at the speed of a trotting dog. Behind us,
perhaps forever, lie the Cities of Men with their
teacups and their brass bedsteads. I am going forth of
my own volition to join the ghosts of Bering and
55 poor Franklin, of frozen De Long and his men.
What I am on the brink of knowing, I now see, is not
an ephemeral mathematical spot but myself. The
doctor was right, even though I dislike him.
Fundamentally I am a dangerous madman, and what
60 I do is both a challenge to my egotism and a
surrender to it.

Q. Which choice best describes the narrator’s view of his expedition to the North Pole?

Question is based on the following passage.

This passage is adapted from MacDonald Harris, The Balloonist. ©2011 by The Estate of Donald Heiney. During the summer of 1897, the narrator of this story, afictional Swedish scientist, has set out for the North Pole in a hydrogen powered balloon.

My emotions are complicated and not
readily verifiable. I feel a vast yearning that is
simultaneously a pleasure and a pain. I am certain
of the consummation of this yearning, but I don’t
5 know yet what form it will take, since I do not
understand quite what it is that the yearning desires.
For the first time there is borne in upon me the full
truth of what I myself said to the doctor only an hour
ago: that my motives in this undertaking are not
10 entirely clear. For years, for a lifetime, the machinery
of my destiny has worked in secret to prepare for this
moment; its clockwork has moved exactly toward
this time and place and no other. Rising slowly from
the earth that bore me and gave me sustenance, I am
15 carried helplessly toward an uninhabited and hostile,
or at best indifferent, part of the earth, littered with
the bones of explorers and the wrecks of ships, frozen
supply caches, messages scrawled with chilled fingers
and hidden in cairns that no eye will ever see.
20 Nobody has succeeded in this thing, and many have
died. Yet in freely willing this enterprise, in choosing
this moment and no other when the south wind
will carry me exactly northward at a velocity of
eight knots, I have converted the machinery of my
25 fate into the servant of my will. All this I understand,
as I understand each detail of the technique by which
this is carried out. What I don’t understand is why I
am so intent on going to this particular place. Who
wants the North Pole! What good is it! Can you eat
30 it? Will it carry you from Gothenburg to Malmö like
a railway? The Danish ministers have declared from
their pulpits that participation in polar expeditions is
beneficial to the soul’s eternal well-being, or so I read
in a newspaper. It isn’t clear how this doctrine is to
35 be interpreted, except that the Pole is something
difficult or impossible to attain which must
nevertheless be sought for, because man is
condemned to seek out and know everything
whether or not the knowledge gives him pleasure. In
40 short, it is the same unthinking lust for knowledge
that drove our First Parents out of the garden.
And suppose you were to find it in spite of all, this
wonderful place that everybody is so anxious to stand
on! What would you find? Exactly nothing.
45 A point precisely identical to all the others in a
completely featureless wasteland stretching around it
for hundreds of miles. It is an abstraction, a
mathematical fiction. No one but a Swedish madman
could take the slightest interest in it. Here I am. The
50 wind is still from the south, bearing us steadily
northward at the speed of a trotting dog. Behind us,
perhaps forever, lie the Cities of Men with their
teacups and their brass bedsteads. I am going forth of
my own volition to join the ghosts of Bering and
55 poor Franklin, of frozen De Long and his men.
What I am on the brink of knowing, I now see, is not
an ephemeral mathematical spot but myself. The
doctor was right, even though I dislike him.
Fundamentally I am a dangerous madman, and what
60 I do is both a challenge to my egotism and a
surrender to it.

Q. The question the narrator asks in lines 30-31 (“Will it... railway”) most nearly implies that

Question is based on the following passage.

This passage is adapted from MacDonald Harris, The Balloonist. ©2011 by The Estate of Donald Heiney. During the summer of 1897, the narrator of this story, afictional Swedish scientist, has set out for the North Pole in a hydrogen powered balloon.

My emotions are complicated and not
readily verifiable. I feel a vast yearning that is
simultaneously a pleasure and a pain. I am certain
of the consummation of this yearning, but I don’t
5 know yet what form it will take, since I do not
understand quite what it is that the yearning desires.
For the first time there is borne in upon me the full
truth of what I myself said to the doctor only an hour
ago: that my motives in this undertaking are not
10 entirely clear. For years, for a lifetime, the machinery
of my destiny has worked in secret to prepare for this
moment; its clockwork has moved exactly toward
this time and place and no other. Rising slowly from
the earth that bore me and gave me sustenance, I am
15 carried helplessly toward an uninhabited and hostile,
or at best indifferent, part of the earth, littered with
the bones of explorers and the wrecks of ships, frozen
supply caches, messages scrawled with chilled fingers
and hidden in cairns that no eye will ever see.
20 Nobody has succeeded in this thing, and many have
died. Yet in freely willing this enterprise, in choosing
this moment and no other when the south wind
will carry me exactly northward at a velocity of
eight knots, I have converted the machinery of my
25 fate into the servant of my will. All this I understand,
as I understand each detail of the technique by which
this is carried out. What I don’t understand is why I
am so intent on going to this particular place. Who
wants the North Pole! What good is it! Can you eat
30 it? Will it carry you from Gothenburg to Malmö like
a railway? The Danish ministers have declared from
their pulpits that participation in polar expeditions is
beneficial to the soul’s eternal well-being, or so I read
in a newspaper. It isn’t clear how this doctrine is to
35 be interpreted, except that the Pole is something
difficult or impossible to attain which must
nevertheless be sought for, because man is
condemned to seek out and know everything
whether or not the knowledge gives him pleasure. In
40 short, it is the same unthinking lust for knowledge
that drove our First Parents out of the garden.
And suppose you were to find it in spite of all, this
wonderful place that everybody is so anxious to stand
on! What would you find? Exactly nothing.
45 A point precisely identical to all the others in a
completely featureless wasteland stretching around it
for hundreds of miles. It is an abstraction, a
mathematical fiction. No one but a Swedish madman
could take the slightest interest in it. Here I am. The
50 wind is still from the south, bearing us steadily
northward at the speed of a trotting dog. Behind us,
perhaps forever, lie the Cities of Men with their
teacups and their brass bedsteads. I am going forth of
my own volition to join the ghosts of Bering and
55 poor Franklin, of frozen De Long and his men.
What I am on the brink of knowing, I now see, is not
an ephemeral mathematical spot but myself. The
doctor was right, even though I dislike him.
Fundamentally I am a dangerous madman, and what
60 I do is both a challenge to my egotism and a
surrender to it.

Q. As used in line 49, “take the slightest interest in” most nearly means

Question is based on the following passage.

This passage is adapted from MacDonald Harris, The Balloonist. ©2011 by The Estate of Donald Heiney. During the summer of 1897, the narrator of this story, afictional Swedish scientist, has set out for the North Pole in a hydrogen powered balloon.

My emotions are complicated and not
readily verifiable. I feel a vast yearning that is
simultaneously a pleasure and a pain. I am certain
of the consummation of this yearning, but I don’t
5 know yet what form it will take, since I do not
understand quite what it is that the yearning desires.
For the first time there is borne in upon me the full
truth of what I myself said to the doctor only an hour
ago: that my motives in this undertaking are not
10 entirely clear. For years, for a lifetime, the machinery
of my destiny has worked in secret to prepare for this
moment; its clockwork has moved exactly toward
this time and place and no other. Rising slowly from
the earth that bore me and gave me sustenance, I am
15 carried helplessly toward an uninhabited and hostile,
or at best indifferent, part of the earth, littered with
the bones of explorers and the wrecks of ships, frozen
supply caches, messages scrawled with chilled fingers
and hidden in cairns that no eye will ever see.
20 Nobody has succeeded in this thing, and many have
died. Yet in freely willing this enterprise, in choosing
this moment and no other when the south wind
will carry me exactly northward at a velocity of
eight knots, I have converted the machinery of my
25 fate into the servant of my will. All this I understand,
as I understand each detail of the technique by which
this is carried out. What I don’t understand is why I
am so intent on going to this particular place. Who
wants the North Pole! What good is it! Can you eat
30 it? Will it carry you from Gothenburg to Malmö like
a railway? The Danish ministers have declared from
their pulpits that participation in polar expeditions is
beneficial to the soul’s eternal well-being, or so I read
in a newspaper. It isn’t clear how this doctrine is to
35 be interpreted, except that the Pole is something
difficult or impossible to attain which must
nevertheless be sought for, because man is
condemned to seek out and know everything
whether or not the knowledge gives him pleasure. In
40 short, it is the same unthinking lust for knowledge
that drove our First Parents out of the garden.
And suppose you were to find it in spite of all, this
wonderful place that everybody is so anxious to stand
on! What would you find? Exactly nothing.
45 A point precisely identical to all the others in a
completely featureless wasteland stretching around it
for hundreds of miles. It is an abstraction, a
mathematical fiction. No one but a Swedish madman
could take the slightest interest in it. Here I am. The
50 wind is still from the south, bearing us steadily
northward at the speed of a trotting dog. Behind us,
perhaps forever, lie the Cities of Men with their
teacups and their brass bedsteads. I am going forth of
my own volition to join the ghosts of Bering and
55 poor Franklin, of frozen De Long and his men.
What I am on the brink of knowing, I now see, is not
an ephemeral mathematical spot but myself. The
doctor was right, even though I dislike him.
Fundamentally I am a dangerous madman, and what
60 I do is both a challenge to my egotism and a
surrender to it.

Q. As used in line 50, “bearing” most nearly means

Question is based on the following passage.

This passage is adapted from Emily Anthes, Frankenstein's Cat. ©2013 by Emily Anthes.
When scientists first learned how to edit the
genomes of animals, they began to imagine all the
ways they could use this new power. Creating
brightly colored novelty pets was not a high priority.
5 Instead, most researchers envisioned far more
consequential applications, hoping to create
genetically engineered animals that saved human
lives. One enterprise is now delivering on this dream.
Welcome to the world of “pharming,” in which
10 simple genetic tweaks turn animals into living
pharmaceutical factories.
Many of the proteins that our cells crank out
naturally make for good medicine. Our bodies’ own
enzymes, hormones, clotting factors, and antibodies
15 are commonly used to treat cancer, diabetes,
autoimmune diseases, and more. The trouble is that
it’s difficult and expensive to make these compounds
on an industrial scale, and as a result, patients can
face shortages of the medicines they need. Dairy
20 animals, on the other hand, are expert protein
producers, their udders swollen with milk. So the
creation of the first transgenic animals—first mice,
then other species—in the 1980s gave scientists an
idea: What if they put the gene for a human antibody
25 or enzyme into a cow, goat, or sheep? If they put the
gene in just the right place, under the control of the
right molecular switch, maybe they could engineer
animals that produced healing human proteins in
their milk. Then doctors could collect medicine by
30 the bucketful.
Throughout the 1980s and ’90s, studies provided
proof of principle, as scientists created transgenic
mice, sheep, goats, pigs, cattle, and rabbits that did in
fact make therapeutic compounds in their milk.
35 At first, this work was merely gee-whiz, scientific
geekery, lab-bound thought experiments come true.
That all changed with ATryn, a drug produced by the
Massachusetts firm GTC Biotherapeutics. ATryn is
antithrombin, an anticoagulant that can be used to
40 prevent life-threatening blood clots. The compound,
made by our liver cells, plays a key role in keeping
our bodies clot-free. It acts as a molecular bouncer,
sidling up to clot-forming compounds and escorting
them out of the bloodstream. But as many as 1 in
45 2,000 Americans are born with a genetic mutation
that prevents them from making antithrombin.
These patients are prone to clots, especially in their
legs and lungs, and they are at elevated risk of
suffering from fatal complications during surgery
50 and childbirth. Supplemental antithrombin can
reduce this risk, and GTC decided to try to
manufacture the compound using genetically
engineered goats.
To create its special herd of goats, GTC used
55 microinjection, the same technique that produced
GloFish and AquAdvantage salmon. The company’s
scientists took the gene for human antithrombin and
injected it directly into fertilized goat eggs. Then they
implanted the eggs in the wombs of female goats.
60 When the kids were born, some of them proved to be
transgenic, the human gene nestled safely in their
cells. The researchers paired the antithrombin gene
with a promoter (which is a sequence of DNA that
controls gene activity) that is normally active in the
65 goat’s mammary glands during milk production.
When the transgenic females lactated, the promoter
turned the transgene on and the goats’ udders filled
with milk containing antithrombin. All that was left
to do was to collect the milk, and extract and purify
70 the protein. Et voilà—human medicine! And, for
GTC, liquid gold. ATryn hit the market in 2006,
becoming the world’s first transgenic animal drug.
Over the course of a year, the “milking parlors” on
GTC’s 300-acre farm in Massachusetts can collect
75 more than a kilogram of medicine from a single
animal.

Q. The primary purpose of the passage is to

Question is based on the following passage.

This passage is adapted from Emily Anthes, Frankenstein's Cat. ©2013 by Emily Anthes.
When scientists first learned how to edit the
genomes of animals, they began to imagine all the
ways they could use this new power. Creating
brightly colored novelty pets was not a high priority.
5 Instead, most researchers envisioned far more
consequential applications, hoping to create
genetically engineered animals that saved human
lives. One enterprise is now delivering on this dream.
Welcome to the world of “pharming,” in which
10 simple genetic tweaks turn animals into living
pharmaceutical factories.
Many of the proteins that our cells crank out
naturally make for good medicine. Our bodies’ own
enzymes, hormones, clotting factors, and antibodies
15 are commonly used to treat cancer, diabetes,
autoimmune diseases, and more. The trouble is that
it’s difficult and expensive to make these compounds
on an industrial scale, and as a result, patients can
face shortages of the medicines they need. Dairy
20 animals, on the other hand, are expert protein
producers, their udders swollen with milk. So the
creation of the first transgenic animals—first mice,
then other species—in the 1980s gave scientists an
idea: What if they put the gene for a human antibody
25 or enzyme into a cow, goat, or sheep? If they put the
gene in just the right place, under the control of the
right molecular switch, maybe they could engineer
animals that produced healing human proteins in
their milk. Then doctors could collect medicine by
30 the bucketful.
Throughout the 1980s and ’90s, studies provided
proof of principle, as scientists created transgenic
mice, sheep, goats, pigs, cattle, and rabbits that did in
fact make therapeutic compounds in their milk.
35 At first, this work was merely gee-whiz, scientific
geekery, lab-bound thought experiments come true.
That all changed with ATryn, a drug produced by the
Massachusetts firm GTC Biotherapeutics. ATryn is
antithrombin, an anticoagulant that can be used to
40 prevent life-threatening blood clots. The compound,
made by our liver cells, plays a key role in keeping
our bodies clot-free. It acts as a molecular bouncer,
sidling up to clot-forming compounds and escorting
them out of the bloodstream. But as many as 1 in
45 2,000 Americans are born with a genetic mutation
that prevents them from making antithrombin.
These patients are prone to clots, especially in their
legs and lungs, and they are at elevated risk of
suffering from fatal complications during surgery
50 and childbirth. Supplemental antithrombin can
reduce this risk, and GTC decided to try to
manufacture the compound using genetically
engineered goats.
To create its special herd of goats, GTC used
55 microinjection, the same technique that produced
GloFish and AquAdvantage salmon. The company’s
scientists took the gene for human antithrombin and
injected it directly into fertilized goat eggs. Then they
implanted the eggs in the wombs of female goats.
60 When the kids were born, some of them proved to be
transgenic, the human gene nestled safely in their
cells. The researchers paired the antithrombin gene
with a promoter (which is a sequence of DNA that
controls gene activity) that is normally active in the
65 goat’s mammary glands during milk production.
When the transgenic females lactated, the promoter
turned the transgene on and the goats’ udders filled
with milk containing antithrombin. All that was left
to do was to collect the milk, and extract and purify
70 the protein. Et voilà—human medicine! And, for
GTC, liquid gold. ATryn hit the market in 2006,
becoming the world’s first transgenic animal drug.
Over the course of a year, the “milking parlors” on
GTC’s 300-acre farm in Massachusetts can collect
75 more than a kilogram of medicine from a single
animal.

Q. The author’s attitude toward pharming is best described as one of

Question is based on the following passage.

This passage is adapted from Emily Anthes, Frankenstein's Cat. ©2013 by Emily Anthes.
When scientists first learned how to edit the
genomes of animals, they began to imagine all the
ways they could use this new power. Creating
brightly colored novelty pets was not a high priority.
5 Instead, most researchers envisioned far more
consequential applications, hoping to create
genetically engineered animals that saved human
lives. One enterprise is now delivering on this dream.
Welcome to the world of “pharming,” in which
10 simple genetic tweaks turn animals into living
pharmaceutical factories.
Many of the proteins that our cells crank out
naturally make for good medicine. Our bodies’ own
enzymes, hormones, clotting factors, and antibodies
15 are commonly used to treat cancer, diabetes,
autoimmune diseases, and more. The trouble is that
it’s difficult and expensive to make these compounds
on an industrial scale, and as a result, patients can
face shortages of the medicines they need. Dairy
20 animals, on the other hand, are expert protein
producers, their udders swollen with milk. So the
creation of the first transgenic animals—first mice,
then other species—in the 1980s gave scientists an
idea: What if they put the gene for a human antibody
25 or enzyme into a cow, goat, or sheep? If they put the
gene in just the right place, under the control of the
right molecular switch, maybe they could engineer
animals that produced healing human proteins in
their milk. Then doctors could collect medicine by
30 the bucketful.
Throughout the 1980s and ’90s, studies provided
proof of principle, as scientists created transgenic
mice, sheep, goats, pigs, cattle, and rabbits that did in
fact make therapeutic compounds in their milk.
35 At first, this work was merely gee-whiz, scientific
geekery, lab-bound thought experiments come true.
That all changed with ATryn, a drug produced by the
Massachusetts firm GTC Biotherapeutics. ATryn is
antithrombin, an anticoagulant that can be used to
40 prevent life-threatening blood clots. The compound,
made by our liver cells, plays a key role in keeping
our bodies clot-free. It acts as a molecular bouncer,
sidling up to clot-forming compounds and escorting
them out of the bloodstream. But as many as 1 in
45 2,000 Americans are born with a genetic mutation
that prevents them from making antithrombin.
These patients are prone to clots, especially in their
legs and lungs, and they are at elevated risk of
suffering from fatal complications during surgery
50 and childbirth. Supplemental antithrombin can
reduce this risk, and GTC decided to try to
manufacture the compound using genetically
engineered goats.
To create its special herd of goats, GTC used
55 microinjection, the same technique that produced
GloFish and AquAdvantage salmon. The company’s
scientists took the gene for human antithrombin and
injected it directly into fertilized goat eggs. Then they
implanted the eggs in the wombs of female goats.
60 When the kids were born, some of them proved to be
transgenic, the human gene nestled safely in their
cells. The researchers paired the antithrombin gene
with a promoter (which is a sequence of DNA that
controls gene activity) that is normally active in the
65 goat’s mammary glands during milk production.
When the transgenic females lactated, the promoter
turned the transgene on and the goats’ udders filled
with milk containing antithrombin. All that was left
to do was to collect the milk, and extract and purify
70 the protein. Et voilà—human medicine! And, for
GTC, liquid gold. ATryn hit the market in 2006,
becoming the world’s first transgenic animal drug.
Over the course of a year, the “milking parlors” on
GTC’s 300-acre farm in Massachusetts can collect
75 more than a kilogram of medicine from a single
animal.

Q. As used in line 20, “expert” most nearly means

Question is based on the following passage.

This passage is adapted from Emily Anthes, Frankenstein's Cat. ©2013 by Emily Anthes.
When scientists first learned how to edit the
genomes of animals, they began to imagine all the
ways they could use this new power. Creating
brightly colored novelty pets was not a high priority.
5 Instead, most researchers envisioned far more
consequential applications, hoping to create
genetically engineered animals that saved human
lives. One enterprise is now delivering on this dream.
Welcome to the world of “pharming,” in which
10 simple genetic tweaks turn animals into living
pharmaceutical factories.
Many of the proteins that our cells crank out
naturally make for good medicine. Our bodies’ own
enzymes, hormones, clotting factors, and antibodies
15 are commonly used to treat cancer, diabetes,
autoimmune diseases, and more. The trouble is that
it’s difficult and expensive to make these compounds
on an industrial scale, and as a result, patients can
face shortages of the medicines they need. Dairy
20 animals, on the other hand, are expert protein
producers, their udders swollen with milk. So the
creation of the first transgenic animals—first mice,
then other species—in the 1980s gave scientists an
idea: What if they put the gene for a human antibody
25 or enzyme into a cow, goat, or sheep? If they put the
gene in just the right place, under the control of the
right molecular switch, maybe they could engineer
animals that produced healing human proteins in
their milk. Then doctors could collect medicine by
30 the bucketful.
Throughout the 1980s and ’90s, studies provided
proof of principle, as scientists created transgenic
mice, sheep, goats, pigs, cattle, and rabbits that did in
fact make therapeutic compounds in their milk.
35 At first, this work was merely gee-whiz, scientific
geekery, lab-bound thought experiments come true.
That all changed with ATryn, a drug produced by the
Massachusetts firm GTC Biotherapeutics. ATryn is
antithrombin, an anticoagulant that can be used to
40 prevent life-threatening blood clots. The compound,
made by our liver cells, plays a key role in keeping
our bodies clot-free. It acts as a molecular bouncer,
sidling up to clot-forming compounds and escorting
them out of the bloodstream. But as many as 1 in
45 2,000 Americans are born with a genetic mutation
that prevents them from making antithrombin.
These patients are prone to clots, especially in their
legs and lungs, and they are at elevated risk of
suffering from fatal complications during surgery
50 and childbirth. Supplemental antithrombin can
reduce this risk, and GTC decided to try to
manufacture the compound using genetically
engineered goats.
To create its special herd of goats, GTC used
55 microinjection, the same technique that produced
GloFish and AquAdvantage salmon. The company’s
scientists took the gene for human antithrombin and
injected it directly into fertilized goat eggs. Then they
implanted the eggs in the wombs of female goats.
60 When the kids were born, some of them proved to be
transgenic, the human gene nestled safely in their
cells. The researchers paired the antithrombin gene
with a promoter (which is a sequence of DNA that
controls gene activity) that is normally active in the
65 goat’s mammary glands during milk production.
When the transgenic females lactated, the promoter
turned the transgene on and the goats’ udders filled
with milk containing antithrombin. All that was left
to do was to collect the milk, and extract and purify
70 the protein. Et voilà—human medicine! And, for
GTC, liquid gold. ATryn hit the market in 2006,
becoming the world’s first transgenic animal drug.
Over the course of a year, the “milking parlors” on
GTC’s 300-acre farm in Massachusetts can collect
75 more than a kilogram of medicine from a single
animal.

Q. What does the author suggest about the transgenic studies done in the 1980s and 1990s?

Question is based on the following passage.

This passage is adapted from Emily Anthes, Frankenstein's Cat. ©2013 by Emily Anthes.
When scientists first learned how to edit the
genomes of animals, they began to imagine all the
ways they could use this new power. Creating
brightly colored novelty pets was not a high priority.
5 Instead, most researchers envisioned far more
consequential applications, hoping to create
genetically engineered animals that saved human
lives. One enterprise is now delivering on this dream.
Welcome to the world of “pharming,” in which
10 simple genetic tweaks turn animals into living
pharmaceutical factories.
Many of the proteins that our cells crank out
naturally make for good medicine. Our bodies’ own
enzymes, hormones, clotting factors, and antibodies
15 are commonly used to treat cancer, diabetes,
autoimmune diseases, and more. The trouble is that
it’s difficult and expensive to make these compounds
on an industrial scale, and as a result, patients can
face shortages of the medicines they need. Dairy
20 animals, on the other hand, are expert protein
producers, their udders swollen with milk. So the
creation of the first transgenic animals—first mice,
then other species—in the 1980s gave scientists an
idea: What if they put the gene for a human antibody
25 or enzyme into a cow, goat, or sheep? If they put the
gene in just the right place, under the control of the
right molecular switch, maybe they could engineer
animals that produced healing human proteins in
their milk. Then doctors could collect medicine by
30 the bucketful.
Throughout the 1980s and ’90s, studies provided
proof of principle, as scientists created transgenic
mice, sheep, goats, pigs, cattle, and rabbits that did in
fact make therapeutic compounds in their milk.
35 At first, this work was merely gee-whiz, scientific
geekery, lab-bound thought experiments come true.
That all changed with ATryn, a drug produced by the
Massachusetts firm GTC Biotherapeutics. ATryn is
antithrombin, an anticoagulant that can be used to
40 prevent life-threatening blood clots. The compound,
made by our liver cells, plays a key role in keeping
our bodies clot-free. It acts as a molecular bouncer,
sidling up to clot-forming compounds and escorting
them out of the bloodstream. But as many as 1 in
45 2,000 Americans are born with a genetic mutation
that prevents them from making antithrombin.
These patients are prone to clots, especially in their
legs and lungs, and they are at elevated risk of
suffering from fatal complications during surgery
50 and childbirth. Supplemental antithrombin can
reduce this risk, and GTC decided to try to
manufacture the compound using genetically
engineered goats.
To create its special herd of goats, GTC used
55 microinjection, the same technique that produced
GloFish and AquAdvantage salmon. The company’s
scientists took the gene for human antithrombin and
injected it directly into fertilized goat eggs. Then they
implanted the eggs in the wombs of female goats.
60 When the kids were born, some of them proved to be
transgenic, the human gene nestled safely in their
cells. The researchers paired the antithrombin gene
with a promoter (which is a sequence of DNA that
controls gene activity) that is normally active in the
65 goat’s mammary glands during milk production.
When the transgenic females lactated, the promoter
turned the transgene on and the goats’ udders filled
with milk containing antithrombin. All that was left
to do was to collect the milk, and extract and purify
70 the protein. Et voilà—human medicine! And, for
GTC, liquid gold. ATryn hit the market in 2006,
becoming the world’s first transgenic animal drug.
Over the course of a year, the “milking parlors” on
GTC’s 300-acre farm in Massachusetts can collect
75 more than a kilogram of medicine from a single
animal.

Q. Which choice provides the best evidence for the answer to the previous question?

Question is based on the following passage.

This passage is adapted from Emily Anthes, Frankenstein's Cat. ©2013 by Emily Anthes.
When scientists first learned how to edit the
genomes of animals, they began to imagine all the
ways they could use this new power. Creating
brightly colored novelty pets was not a high priority.
5 Instead, most researchers envisioned far more
consequential applications, hoping to create
genetically engineered animals that saved human
lives. One enterprise is now delivering on this dream.
Welcome to the world of “pharming,” in which
10 simple genetic tweaks turn animals into living
pharmaceutical factories.
Many of the proteins that our cells crank out
naturally make for good medicine. Our bodies’ own
enzymes, hormones, clotting factors, and antibodies
15 are commonly used to treat cancer, diabetes,
autoimmune diseases, and more. The trouble is that
it’s difficult and expensive to make these compounds
on an industrial scale, and as a result, patients can
face shortages of the medicines they need. Dairy
20 animals, on the other hand, are expert protein
producers, their udders swollen with milk. So the
creation of the first transgenic animals—first mice,
then other species—in the 1980s gave scientists an
idea: What if they put the gene for a human antibody
25 or enzyme into a cow, goat, or sheep? If they put the
gene in just the right place, under the control of the
right molecular switch, maybe they could engineer
animals that produced healing human proteins in
their milk. Then doctors could collect medicine by
30 the bucketful.
Throughout the 1980s and ’90s, studies provided
proof of principle, as scientists created transgenic
mice, sheep, goats, pigs, cattle, and rabbits that did in
fact make therapeutic compounds in their milk.
35 At first, this work was merely gee-whiz, scientific
geekery, lab-bound thought experiments come true.
That all changed with ATryn, a drug produced by the
Massachusetts firm GTC Biotherapeutics. ATryn is
antithrombin, an anticoagulant that can be used to
40 prevent life-threatening blood clots. The compound,
made by our liver cells, plays a key role in keeping
our bodies clot-free. It acts as a molecular bouncer,
sidling up to clot-forming compounds and escorting
them out of the bloodstream. But as many as 1 in
45 2,000 Americans are born with a genetic mutation
that prevents them from making antithrombin.
These patients are prone to clots, especially in their
legs and lungs, and they are at elevated risk of
suffering from fatal complications during surgery
50 and childbirth. Supplemental antithrombin can
reduce this risk, and GTC decided to try to
manufacture the compound using genetically
engineered goats.
To create its special herd of goats, GTC used
55 microinjection, the same technique that produced
GloFish and AquAdvantage salmon. The company’s
scientists took the gene for human antithrombin and
injected it directly into fertilized goat eggs. Then they
implanted the eggs in the wombs of female goats.
60 When the kids were born, some of them proved to be
transgenic, the human gene nestled safely in their
cells. The researchers paired the antithrombin gene
with a promoter (which is a sequence of DNA that
controls gene activity) that is normally active in the
65 goat’s mammary glands during milk production.
When the transgenic females lactated, the promoter
turned the transgene on and the goats’ udders filled
with milk containing antithrombin. All that was left
to do was to collect the milk, and extract and purify
70 the protein. Et voilà—human medicine! And, for
GTC, liquid gold. ATryn hit the market in 2006,
becoming the world’s first transgenic animal drug.
Over the course of a year, the “milking parlors” on
GTC’s 300-acre farm in Massachusetts can collect
75 more than a kilogram of medicine from a single
animal.

Q. According to the passage, which of the following is true of antithrombin?

Question is based on the following passage.

This passage is adapted from Emily Anthes, Frankenstein's Cat. ©2013 by Emily Anthes.
When scientists first learned how to edit the
genomes of animals, they began to imagine all the
ways they could use this new power. Creating
brightly colored novelty pets was not a high priority.
5 Instead, most researchers envisioned far more
consequential applications, hoping to create
genetically engineered animals that saved human
lives. One enterprise is now delivering on this dream.
Welcome to the world of “pharming,” in which
10 simple genetic tweaks turn animals into living
pharmaceutical factories.
Many of the proteins that our cells crank out
naturally make for good medicine. Our bodies’ own
enzymes, hormones, clotting factors, and antibodies
15 are commonly used to treat cancer, diabetes,
autoimmune diseases, and more. The trouble is that
it’s difficult and expensive to make these compounds
on an industrial scale, and as a result, patients can
face shortages of the medicines they need. Dairy
20 animals, on the other hand, are expert protein
producers, their udders swollen with milk. So the
creation of the first transgenic animals—first mice,
then other species—in the 1980s gave scientists an
idea: What if they put the gene for a human antibody
25 or enzyme into a cow, goat, or sheep? If they put the
gene in just the right place, under the control of the
right molecular switch, maybe they could engineer
animals that produced healing human proteins in
their milk. Then doctors could collect medicine by
30 the bucketful.
Throughout the 1980s and ’90s, studies provided
proof of principle, as scientists created transgenic
mice, sheep, goats, pigs, cattle, and rabbits that did in
fact make therapeutic compounds in their milk.
35 At first, this work was merely gee-whiz, scientific
geekery, lab-bound thought experiments come true.
That all changed with ATryn, a drug produced by the
Massachusetts firm GTC Biotherapeutics. ATryn is
antithrombin, an anticoagulant that can be used to
40 prevent life-threatening blood clots. The compound,
made by our liver cells, plays a key role in keeping
our bodies clot-free. It acts as a molecular bouncer,
sidling up to clot-forming compounds and escorting
them out of the bloodstream. But as many as 1 in
45 2,000 Americans are born with a genetic mutation
that prevents them from making antithrombin.
These patients are prone to clots, especially in their
legs and lungs, and they are at elevated risk of
suffering from fatal complications during surgery
50 and childbirth. Supplemental antithrombin can
reduce this risk, and GTC decided to try to
manufacture the compound using genetically
engineered goats.
To create its special herd of goats, GTC used
55 microinjection, the same technique that produced
GloFish and AquAdvantage salmon. The company’s
scientists took the gene for human antithrombin and
injected it directly into fertilized goat eggs. Then they
implanted the eggs in the wombs of female goats.
60 When the kids were born, some of them proved to be
transgenic, the human gene nestled safely in their
cells. The researchers paired the antithrombin gene
with a promoter (which is a sequence of DNA that
controls gene activity) that is normally active in the
65 goat’s mammary glands during milk production.
When the transgenic females lactated, the promoter
turned the transgene on and the goats’ udders filled
with milk containing antithrombin. All that was left
to do was to collect the milk, and extract and purify
70 the protein. Et voilà—human medicine! And, for
GTC, liquid gold. ATryn hit the market in 2006,
becoming the world’s first transgenic animal drug.
Over the course of a year, the “milking parlors” on
GTC’s 300-acre farm in Massachusetts can collect
75 more than a kilogram of medicine from a single
animal.

Q. Which choice provides the best evidence for the answer to the previous question?

Question is based on the following passage.

This passage is adapted from Emily Anthes, Frankenstein's Cat. ©2013 by Emily Anthes.
When scientists first learned how to edit the
genomes of animals, they began to imagine all the
ways they could use this new power. Creating
brightly colored novelty pets was not a high priority.
5 Instead, most researchers envisioned far more
consequential applications, hoping to create
genetically engineered animals that saved human
lives. One enterprise is now delivering on this dream.
Welcome to the world of “pharming,” in which
10 simple genetic tweaks turn animals into living
pharmaceutical factories.
Many of the proteins that our cells crank out
naturally make for good medicine. Our bodies’ own
enzymes, hormones, clotting factors, and antibodies
15 are commonly used to treat cancer, diabetes,
autoimmune diseases, and more. The trouble is that
it’s difficult and expensive to make these compounds
on an industrial scale, and as a result, patients can
face shortages of the medicines they need. Dairy
20 animals, on the other hand, are expert protein
producers, their udders swollen with milk. So the
creation of the first transgenic animals—first mice,
then other species—in the 1980s gave scientists an
idea: What if they put the gene for a human antibody
25 or enzyme into a cow, goat, or sheep? If they put the
gene in just the right place, under the control of the
right molecular switch, maybe they could engineer
animals that produced healing human proteins in
their milk. Then doctors could collect medicine by
30 the bucketful.
Throughout the 1980s and ’90s, studies provided
proof of principle, as scientists created transgenic
mice, sheep, goats, pigs, cattle, and rabbits that did in
fact make therapeutic compounds in their milk.
35 At first, this work was merely gee-whiz, scientific
geekery, lab-bound thought experiments come true.
That all changed with ATryn, a drug produced by the
Massachusetts firm GTC Biotherapeutics. ATryn is
antithrombin, an anticoagulant that can be used to
40 prevent life-threatening blood clots. The compound,
made by our liver cells, plays a key role in keeping
our bodies clot-free. It acts as a molecular bouncer,
sidling up to clot-forming compounds and escorting
them out of the bloodstream. But as many as 1 in
45 2,000 Americans are born with a genetic mutation
that prevents them from making antithrombin.
These patients are prone to clots, especially in their
legs and lungs, and they are at elevated risk of
suffering from fatal complications during surgery
50 and childbirth. Supplemental antithrombin can
reduce this risk, and GTC decided to try to
manufacture the compound using genetically
engineered goats.
To create its special herd of goats, GTC used
55 microinjection, the same technique that produced
GloFish and AquAdvantage salmon. The company’s
scientists took the gene for human antithrombin and
injected it directly into fertilized goat eggs. Then they
implanted the eggs in the wombs of female goats.
60 When the kids were born, some of them proved to be
transgenic, the human gene nestled safely in their
cells. The researchers paired the antithrombin gene
with a promoter (which is a sequence of DNA that
controls gene activity) that is normally active in the
65 goat’s mammary glands during milk production.
When the transgenic females lactated, the promoter
turned the transgene on and the goats’ udders filled
with milk containing antithrombin. All that was left
to do was to collect the milk, and extract and purify
70 the protein. Et voilà—human medicine! And, for
GTC, liquid gold. ATryn hit the market in 2006,
becoming the world’s first transgenic animal drug.
Over the course of a year, the “milking parlors” on
GTC’s 300-acre farm in Massachusetts can collect
75 more than a kilogram of medicine from a single
animal.

Q. Which of the following does the author suggest about the “female goats” mentioned in line 59?

Question is based on the following passage.

This passage is adapted from Emily Anthes, Frankenstein's Cat. ©2013 by Emily Anthes.
When scientists first learned how to edit the
genomes of animals, they began to imagine all the
ways they could use this new power. Creating
brightly colored novelty pets was not a high priority.
5 Instead, most researchers envisioned far more
consequential applications, hoping to create
genetically engineered animals that saved human
lives. One enterprise is now delivering on this dream.
Welcome to the world of “pharming,” in which
10 simple genetic tweaks turn animals into living
pharmaceutical factories.
Many of the proteins that our cells crank out
naturally make for good medicine. Our bodies’ own
enzymes, hormones, clotting factors, and antibodies
15 are commonly used to treat cancer, diabetes,
autoimmune diseases, and more. The trouble is that
it’s difficult and expensive to make these compounds
on an industrial scale, and as a result, patients can
face shortages of the medicines they need. Dairy
20 animals, on the other hand, are expert protein
producers, their udders swollen with milk. So the
creation of the first transgenic animals—first mice,
then other species—in the 1980s gave scientists an
idea: What if they put the gene for a human antibody
25 or enzyme into a cow, goat, or sheep? If they put the
gene in just the right place, under the control of the
right molecular switch, maybe they could engineer
animals that produced healing human proteins in
their milk. Then doctors could collect medicine by
30 the bucketful.
Throughout the 1980s and ’90s, studies provided
proof of principle, as scientists created transgenic
mice, sheep, goats, pigs, cattle, and rabbits that did in
fact make therapeutic compounds in their milk.
35 At first, this work was merely gee-whiz, scientific
geekery, lab-bound thought experiments come true.
That all changed with ATryn, a drug produced by the
Massachusetts firm GTC Biotherapeutics. ATryn is
antithrombin, an anticoagulant that can be used to
40 prevent life-threatening blood clots. The compound,
made by our liver cells, plays a key role in keeping
our bodies clot-free. It acts as a molecular bouncer,
sidling up to clot-forming compounds and escorting
them out of the bloodstream. But as many as 1 in
45 2,000 Americans are born with a genetic mutation
that prevents them from making antithrombin.
These patients are prone to clots, especially in their
legs and lungs, and they are at elevated risk of
suffering from fatal complications during surgery
50 and childbirth. Supplemental antithrombin can
reduce this risk, and GTC decided to try to
manufacture the compound using genetically
engineered goats.
To create its special herd of goats, GTC used
55 microinjection, the same technique that produced
GloFish and AquAdvantage salmon. The company’s
scientists took the gene for human antithrombin and
injected it directly into fertilized goat eggs. Then they
implanted the eggs in the wombs of female goats.
60 When the kids were born, some of them proved to be
transgenic, the human gene nestled safely in their
cells. The researchers paired the antithrombin gene
with a promoter (which is a sequence of DNA that
controls gene activity) that is normally active in the
65 goat’s mammary glands during milk production.
When the transgenic females lactated, the promoter
turned the transgene on and the goats’ udders filled
with milk containing antithrombin. All that was left
to do was to collect the milk, and extract and purify
70 the protein. Et voilà—human medicine! And, for
GTC, liquid gold. ATryn hit the market in 2006,
becoming the world’s first transgenic animal drug.
Over the course of a year, the “milking parlors” on
GTC’s 300-acre farm in Massachusetts can collect
75 more than a kilogram of medicine from a single
animal.

Q. The most likely purpose of the parenthetical information in lines 63-64 is to

Question is based on the following passage.

This passage is adapted from Emily Anthes, Frankenstein's Cat. ©2013 by Emily Anthes.
When scientists first learned how to edit the
genomes of animals, they began to imagine all the
ways they could use this new power. Creating
brightly colored novelty pets was not a high priority.
5 Instead, most researchers envisioned far more
consequential applications, hoping to create
genetically engineered animals that saved human
lives. One enterprise is now delivering on this dream.
Welcome to the world of “pharming,” in which
10 simple genetic tweaks turn animals into living
pharmaceutical factories.
Many of the proteins that our cells crank out
naturally make for good medicine. Our bodies’ own
enzymes, hormones, clotting factors, and antibodies
15 are commonly used to treat cancer, diabetes,
autoimmune diseases, and more. The trouble is that
it’s difficult and expensive to make these compounds
on an industrial scale, and as a result, patients can
face shortages of the medicines they need. Dairy
20 animals, on the other hand, are expert protein
producers, their udders swollen with milk. So the
creation of the first transgenic animals—first mice,
then other species—in the 1980s gave scientists an
idea: What if they put the gene for a human antibody
25 or enzyme into a cow, goat, or sheep? If they put the
gene in just the right place, under the control of the
right molecular switch, maybe they could engineer
animals that produced healing human proteins in
their milk. Then doctors could collect medicine by
30 the bucketful.
Throughout the 1980s and ’90s, studies provided
proof of principle, as scientists created transgenic
mice, sheep, goats, pigs, cattle, and rabbits that did in
fact make therapeutic compounds in their milk.
35 At first, this work was merely gee-whiz, scientific
geekery, lab-bound thought experiments come true.
That all changed with ATryn, a drug produced by the
Massachusetts firm GTC Biotherapeutics. ATryn is
antithrombin, an anticoagulant that can be used to
40 prevent life-threatening blood clots. The compound,
made by our liver cells, plays a key role in keeping
our bodies clot-free. It acts as a molecular bouncer,
sidling up to clot-forming compounds and escorting
them out of the bloodstream. But as many as 1 in
45 2,000 Americans are born with a genetic mutation
that prevents them from making antithrombin.
These patients are prone to clots, especially in their
legs and lungs, and they are at elevated risk of
suffering from fatal complications during surgery
50 and childbirth. Supplemental antithrombin can
reduce this risk, and GTC decided to try to
manufacture the compound using genetically
engineered goats.
To create its special herd of goats, GTC used
55 microinjection, the same technique that produced
GloFish and AquAdvantage salmon. The company’s
scientists took the gene for human antithrombin and
injected it directly into fertilized goat eggs. Then they
implanted the eggs in the wombs of female goats.
60 When the kids were born, some of them proved to be
transgenic, the human gene nestled safely in their
cells. The researchers paired the antithrombin gene
with a promoter (which is a sequence of DNA that
controls gene activity) that is normally active in the
65 goat’s mammary glands during milk production.
When the transgenic females lactated, the promoter
turned the transgene on and the goats’ udders filled
with milk containing antithrombin. All that was left
to do was to collect the milk, and extract and purify
70 the protein. Et voilà—human medicine! And, for
GTC, liquid gold. ATryn hit the market in 2006,
becoming the world’s first transgenic animal drug.
Over the course of a year, the “milking parlors” on
GTC’s 300-acre farm in Massachusetts can collect
75 more than a kilogram of medicine from a single
animal.

Q. The phrase “liquid gold” (line 71) most directly suggests that