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Test: Molecular Basis of Inheritance - 2


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26 Questions MCQ Test Biology Class 12 | Test: Molecular Basis of Inheritance - 2

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Test: Molecular Basis of Inheritance - 2 - Question 1

Which of the following statements is true about DNA replication?

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 1

DNA molecules are replicated in both meiosis and mitosis.  DNA unwinds and unzips along its base pair chemical bonds.  Free nucleotides then connect to the exposed base pairs on both strands resulting in the formation of the missing side of each new DNA.

Test: Molecular Basis of Inheritance - 2 - Question 2

Beadle and Tatum showed that each kind of mutant bread mould they studied lacked a specific enzyme. Their experiments demonstrated that

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 2

Beadle and Tatum carried out experiment on mutant bread mould that lacked specific enzymes. They demonstrated that gene carry information for making proteins.

Test: Molecular Basis of Inheritance - 2 - Question 3

A single strand of nucleic acid tagged with a radioactive molecule is called?

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 3

A single strand of nucleic acid tagged with a radioactive molecule is calledProbe. Probe is used to know the mechanism of transcription of DNA. Radioactive substance can be easily detected.

Test: Molecular Basis of Inheritance - 2 - Question 4

A phenomenon where the third base of t-RNA at its 5’ end can pair with a non-complementary base of m-RNA is called?

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 4

Wobbling is a phenomenon where the third base of t-RNA at its 5’ end pair with a non-complementary base of m-RNA.

Test: Molecular Basis of Inheritance - 2 - Question 5

What does A & B represent?

   

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 5

In figure above, A represent helicase and B represents single strand binding protein. These structures are formed during semiconservative replication of DNA.

Test: Molecular Basis of Inheritance - 2 - Question 6

Degeneracy of genetic code is due to

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 6

There are 64 codons if genetic code is triplet, total 64 codons are formed in which 3 codon are terminator or stop codon. There are 64-3 61 codons and 20 amino acids. More than one codons code for same amino acids, so, genetic code is degenerate.

Test: Molecular Basis of Inheritance - 2 - Question 7

A DNA segment which serves as a kind of “ON-OFF switch” for transcription is a/an

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 7

The DNA segment which serves as ON-OFF switch for transcription is called an operator. Operator attach with template strand to initiate transcription process.

Test: Molecular Basis of Inheritance - 2 - Question 8

Which one of the following pairs is correctly matched with regard to the codon and the amino acid coded by it?

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 8

Codon AAA code for amino acid lysine but UUA, AUG and CCC do not code for Valine, cysteine and alanine respectively. So, AAA and lysine pair is correct option out of given options.

Test: Molecular Basis of Inheritance - 2 - Question 9

During translation initiation in prokaryotes, a GTP molecule is needed in

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 9

During translation initiation in prokaryotes, a GTP molecule is required along with 30S ribosome, m-RNA with formyl-met-t-RNA. GTP provides energy and ribosomes provide site for translation.

Test: Molecular Basis of Inheritance - 2 - Question 10

Why are UGA, UAG and UAA called termination codons?

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 10

UGA, UAG and UAAare called termination or stop codon because they do not code for any amino acid. As soon as any one of them codon is located on m-RNA translation process is stopped.

Test: Molecular Basis of Inheritance - 2 - Question 11

Removal of introns and joining of exons in a defined order during transcription is called?

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 11

The mRNA produced by transcription of DNA consists of exons and introns. The removal of introns and joining of exons to obtain mature mRNA is called splicing. It is followed by capping and tailing.

Test: Molecular Basis of Inheritance - 2 - Question 12

What does "lac" refer to in what we call the lac operon?

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 12

In lac operon the word lac refers to lactose. A polycistronic structural gene is regulated by a common promoter and regulatory genes.

Test: Molecular Basis of Inheritance - 2 - Question 13

The sequence of structural gene in lac operon concept is

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 13

In lac operon concept the sequence of arrangement of structural gene is as lac Z, lac Y and lac A. The z gene codes for beta-galactosidase. The y gene code for permease and a gene encodes a transacytylase.

Test: Molecular Basis of Inheritance - 2 - Question 14

What does X replesent in the followwing diagram:

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 14

Figure shown above represent translation process in which protein is produced. Ribosome provide site for protein synthesis and t-RNA brings the amino acids. The ‘x’ is the polypeptide chain produced.

Test: Molecular Basis of Inheritance - 2 - Question 15

Autoradiogram of VNTR probe gives many band of different size. It differ from individual to individual except

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 15

Autoradiogram of VNTR probe gives many band of different size. It differs from individual to individual except monozygotic twins or identical twins.

Test: Molecular Basis of Inheritance - 2 - Question 16

In human genome project, commonly used host were bacteria and yeast and their vectors are called as

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 16

In human genome project, commonly used host were bacteria and yeast and their vectors are called as Bacterial artificial chromosome (BAC) and yeast artificial chromosome (YAC)

Test: Molecular Basis of Inheritance - 2 - Question 17

Assertion: Genetic map up of an organism or individual lies in the DNA sequence.

Reason: If two individual differs, then their DNA sequence should also be different.

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 17

Genetic map up of an organism or individual lies in the DNA sequence. If two individual differs, then their DNA sequence should also be different.

Test: Molecular Basis of Inheritance - 2 - Question 18

Rice genome projects includes
a. Fingerprinting of HindIII and Eco RI.
b. Assembly of the fingerprinted BACs into contigs.

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 18

Rice genome projects includes finger printing of HindIII and Eco RI and assembling of finger printed BACs into contigs.

Test: Molecular Basis of Inheritance - 2 - Question 19

Genetic and physical map of genome was generated using information on
a. Polymorphism of restriction endonuclease recognition sites.
b. Repetitive DNA sequence called microsatellites.

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 19

Genetic and physical map of genome was generated using information on polymorphism of restriction endonuclease recognition sites and repetitive DNA sequence called microsatellites.

Test: Molecular Basis of Inheritance - 2 - Question 20

In human genome project, commonly used host were bacteria and yeast and their vectors are called as

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 20

In human genome project, commonly used host were bacteria and yeast and their vectors are called as Bacterial artificial chromosome (BAC) and yeast artificial chromosome (YAC)

Test: Molecular Basis of Inheritance - 2 - Question 21

DNA is made of two chains that twist about one another in the shape of a _______.

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 21

The double helix describes the appearance of double-stranded DNA, which is composed of two linear strands that run opposite to each other, or anti-parallel, and twist together. Each DNA strand within the double helix is a long, linear molecule made of smaller units called nucleotides that form a chain.

Test: Molecular Basis of Inheritance - 2 - Question 22

Assertion: UAA codon is a termination codon.

Reason: If in a mRNA, a termination codon is present, the protein synthesis stops abruptly whether the protein synthesis is complete or not.

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 22

UAA of mRNA do not code for any amino acids so it is a termination codon. If termination codon is present on mRNA, the protein synthesis stops abruptly at that point.

Test: Molecular Basis of Inheritance - 2 - Question 23

The sensitivity of fingerprinting technique has been increased by use of

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 23

The sensitivity of fingerprinting technique has been increased by use of Polymerase chain reaction (PCR). After that single cell obtained from organism in enough for this technique.

Test: Molecular Basis of Inheritance - 2 - Question 24

Statement I: DNA finger printing is highly reliable method of identification of individual involved in crimes.
Statement II: DNA a fingerprinting is a sure method in solving paternity and maternity disputes.
Statement III: DNA fingerprinting can be used to cure HIV infection.

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 24

DNA finger printing is highly reliable method of identification of individual involved in crimes. DNA a fingerprinting is a sure method in solving paternity and maternity disputes.DNA fingerprinting cannot be used to cure HIV infection.

Test: Molecular Basis of Inheritance - 2 - Question 25

The hybridization of probes having radioactive isotopes with various sequence of nitrogen bases with ssVNTR is called?

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 25

The hybridization of probes having radioactive isotopes with various sequence of nitrogen bases with ssVNTR is called Southern blotting.

Test: Molecular Basis of Inheritance - 2 - Question 26

Assertion: VNTR of two persons may be similar at certain sites but could be different at other sites.

Reason: A child inherits 50% of chromosomes from mother and remaining 50% from father.

Detailed Solution for Test: Molecular Basis of Inheritance - 2 - Question 26

VNTR of two persons may be similar at certain sites but could be different at other sites because a child inherits 50% of chromosomes from mother and remaining 50% from father. VNTR genes also undergoes different kinds of mutations.

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