Page 1
Introduction to Cell
Institute of Lifelong Learning, University of Delhi
Lesson: Introduction to cell
Lesson Developer: Manju A.Lal
College/Department: Kirori Mal College, University of Delhi
Page 2
Introduction to Cell
Institute of Lifelong Learning, University of Delhi
Lesson: Introduction to cell
Lesson Developer: Manju A.Lal
College/Department: Kirori Mal College, University of Delhi
Institute of Lifelong Learning, University of Delhi 1
Table of Contents
Chapter: Introduction to Cell
? Cell is unit of life
? Characteristics of a living cell
? History of Cell Biology
? Cell is the basic unit of structure and function
? Cell size
? Cell types
? Prokaryotic cell
? Characteristics
? Diversity of prokaryotes
? Eukaryotic cell
? Infective particles
? Viruses
? Viroids
? Prions
? Summary
? Exercise/ Practice
? Glossary
? References/ Bibliography/ Further Reading
Page 3
Introduction to Cell
Institute of Lifelong Learning, University of Delhi
Lesson: Introduction to cell
Lesson Developer: Manju A.Lal
College/Department: Kirori Mal College, University of Delhi
Institute of Lifelong Learning, University of Delhi 1
Table of Contents
Chapter: Introduction to Cell
? Cell is unit of life
? Characteristics of a living cell
? History of Cell Biology
? Cell is the basic unit of structure and function
? Cell size
? Cell types
? Prokaryotic cell
? Characteristics
? Diversity of prokaryotes
? Eukaryotic cell
? Infective particles
? Viruses
? Viroids
? Prions
? Summary
? Exercise/ Practice
? Glossary
? References/ Bibliography/ Further Reading
Institute of Lifelong Learning, University of Delhi 2
Cell is unit of life
When you see the world around you, a distinction between living and nonliving can be made
immediately. Let us see, how do you distinguish between these two?
The organisms, which are living, are able to grow (i.e., there is increase either in size of the
organism, or in their mass), they can utilize energy from their surrounding for their growth,
and they are able to reproduce i.e. they produce the progeny of their kind.
Figure: You see a great diversity of living organisms both in size, as well as in shape.
Source: http://cimg1.ck12.org/datastreams/f-
d%3A0517ff938b6d399c6c915fba103f142ed29e82bf4e8d71e7deccf02e%2BIMAGE%2BIMA
GE.1 (CC-BY-SA)
Some of the living organisms are so small that you are not able to see them with your
unaided eyes, These are smaller than 0.1 mm and are called microorganisms. Others can be
as big as 300 meters e.g. redwood trees.
Microscopic study of all organisms suggests that they are made up of cells. Like a house, in
which bricks are the basic unit of structure, cells are the basic unit of structure and
function of all the living beings. Some organisms are made up of single cell and are called
unicellular, while others have many cells, so are called multicellular.
In this chapter you will learn about: -
1. The characteristics of a living cell.
2. Discoveries that led to understanding of cell structure and cell
function.
3. How did the concept of cell biology evolve?
Page 4
Introduction to Cell
Institute of Lifelong Learning, University of Delhi
Lesson: Introduction to cell
Lesson Developer: Manju A.Lal
College/Department: Kirori Mal College, University of Delhi
Institute of Lifelong Learning, University of Delhi 1
Table of Contents
Chapter: Introduction to Cell
? Cell is unit of life
? Characteristics of a living cell
? History of Cell Biology
? Cell is the basic unit of structure and function
? Cell size
? Cell types
? Prokaryotic cell
? Characteristics
? Diversity of prokaryotes
? Eukaryotic cell
? Infective particles
? Viruses
? Viroids
? Prions
? Summary
? Exercise/ Practice
? Glossary
? References/ Bibliography/ Further Reading
Institute of Lifelong Learning, University of Delhi 2
Cell is unit of life
When you see the world around you, a distinction between living and nonliving can be made
immediately. Let us see, how do you distinguish between these two?
The organisms, which are living, are able to grow (i.e., there is increase either in size of the
organism, or in their mass), they can utilize energy from their surrounding for their growth,
and they are able to reproduce i.e. they produce the progeny of their kind.
Figure: You see a great diversity of living organisms both in size, as well as in shape.
Source: http://cimg1.ck12.org/datastreams/f-
d%3A0517ff938b6d399c6c915fba103f142ed29e82bf4e8d71e7deccf02e%2BIMAGE%2BIMA
GE.1 (CC-BY-SA)
Some of the living organisms are so small that you are not able to see them with your
unaided eyes, These are smaller than 0.1 mm and are called microorganisms. Others can be
as big as 300 meters e.g. redwood trees.
Microscopic study of all organisms suggests that they are made up of cells. Like a house, in
which bricks are the basic unit of structure, cells are the basic unit of structure and
function of all the living beings. Some organisms are made up of single cell and are called
unicellular, while others have many cells, so are called multicellular.
In this chapter you will learn about: -
1. The characteristics of a living cell.
2. Discoveries that led to understanding of cell structure and cell
function.
3. How did the concept of cell biology evolve?
Institute of Lifelong Learning, University of Delhi 3
4. Cell types and cell sizes.
5. Some of the acellular structures.
Characteristics of living cells
All the living cells have following characteristics:-
? Presence of a membrane around the cell, which restricts entry to only certain
molecules, besides allowing free passage to water and to some of the gases such as
oxygen and carbon-di-oxide. The membrane is able to separate the inside space of
the cell from the surroundings. This helps in keeping the environment of the cell at
optimal level suitable for various chemical reactions occurring inside the living cell.
? The cell has its own energy generating system. The energy, which is produced by the
cell, is conserved in the form of ATP and it is this form of energy, which is utilized for
various life functions.
? A cell has its own genetic information, which it has received from its parent cell.
? The cell has its own machinery by which it can copy, and translate the genetic
information, which is present in it in the form of polymer of nitrogen bases. This
information is translated to the sequence of amino acids of a protein molecule by the
cell machinery.
? The cell is able to produce its own kind i.e. the cell is capable of forming new
daughter cells. In plants this capacity of cell division is limited to the meristematic
tissues, such as stem meristems, root meristems and intercalary meristems.
History of Cell Biology
Discovery of the cell was dependent on the invention and improvement of the microscope,
the equipment used to observe the structures having dimensions lesser than 0.1 mm.
Janssen had invented the first compound microscope in 1590 with the magnification of 9X.
Robert Hooke used it in 1665 for the first time to observe a thin section of cork (cork was
the piece of bark, which is outer dead layer of tree and it was being used as a stopper of the
bottles). He observed that the section was like a honeycomb structure. It had a number of
compartments, which were separated by a wall. He considered the wall as a living structure,
which was enclosing the empty space. These empty spaces were called as „Cells?. He
thought these cells to be the containers of „noble juices? or „fibrous threads? of once living
Page 5
Introduction to Cell
Institute of Lifelong Learning, University of Delhi
Lesson: Introduction to cell
Lesson Developer: Manju A.Lal
College/Department: Kirori Mal College, University of Delhi
Institute of Lifelong Learning, University of Delhi 1
Table of Contents
Chapter: Introduction to Cell
? Cell is unit of life
? Characteristics of a living cell
? History of Cell Biology
? Cell is the basic unit of structure and function
? Cell size
? Cell types
? Prokaryotic cell
? Characteristics
? Diversity of prokaryotes
? Eukaryotic cell
? Infective particles
? Viruses
? Viroids
? Prions
? Summary
? Exercise/ Practice
? Glossary
? References/ Bibliography/ Further Reading
Institute of Lifelong Learning, University of Delhi 2
Cell is unit of life
When you see the world around you, a distinction between living and nonliving can be made
immediately. Let us see, how do you distinguish between these two?
The organisms, which are living, are able to grow (i.e., there is increase either in size of the
organism, or in their mass), they can utilize energy from their surrounding for their growth,
and they are able to reproduce i.e. they produce the progeny of their kind.
Figure: You see a great diversity of living organisms both in size, as well as in shape.
Source: http://cimg1.ck12.org/datastreams/f-
d%3A0517ff938b6d399c6c915fba103f142ed29e82bf4e8d71e7deccf02e%2BIMAGE%2BIMA
GE.1 (CC-BY-SA)
Some of the living organisms are so small that you are not able to see them with your
unaided eyes, These are smaller than 0.1 mm and are called microorganisms. Others can be
as big as 300 meters e.g. redwood trees.
Microscopic study of all organisms suggests that they are made up of cells. Like a house, in
which bricks are the basic unit of structure, cells are the basic unit of structure and
function of all the living beings. Some organisms are made up of single cell and are called
unicellular, while others have many cells, so are called multicellular.
In this chapter you will learn about: -
1. The characteristics of a living cell.
2. Discoveries that led to understanding of cell structure and cell
function.
3. How did the concept of cell biology evolve?
Institute of Lifelong Learning, University of Delhi 3
4. Cell types and cell sizes.
5. Some of the acellular structures.
Characteristics of living cells
All the living cells have following characteristics:-
? Presence of a membrane around the cell, which restricts entry to only certain
molecules, besides allowing free passage to water and to some of the gases such as
oxygen and carbon-di-oxide. The membrane is able to separate the inside space of
the cell from the surroundings. This helps in keeping the environment of the cell at
optimal level suitable for various chemical reactions occurring inside the living cell.
? The cell has its own energy generating system. The energy, which is produced by the
cell, is conserved in the form of ATP and it is this form of energy, which is utilized for
various life functions.
? A cell has its own genetic information, which it has received from its parent cell.
? The cell has its own machinery by which it can copy, and translate the genetic
information, which is present in it in the form of polymer of nitrogen bases. This
information is translated to the sequence of amino acids of a protein molecule by the
cell machinery.
? The cell is able to produce its own kind i.e. the cell is capable of forming new
daughter cells. In plants this capacity of cell division is limited to the meristematic
tissues, such as stem meristems, root meristems and intercalary meristems.
History of Cell Biology
Discovery of the cell was dependent on the invention and improvement of the microscope,
the equipment used to observe the structures having dimensions lesser than 0.1 mm.
Janssen had invented the first compound microscope in 1590 with the magnification of 9X.
Robert Hooke used it in 1665 for the first time to observe a thin section of cork (cork was
the piece of bark, which is outer dead layer of tree and it was being used as a stopper of the
bottles). He observed that the section was like a honeycomb structure. It had a number of
compartments, which were separated by a wall. He considered the wall as a living structure,
which was enclosing the empty space. These empty spaces were called as „Cells?. He
thought these cells to be the containers of „noble juices? or „fibrous threads? of once living
Institute of Lifelong Learning, University of Delhi 4
cork trees. He published his observations made with the microscope in the book
Micrographia.
Figure: Robert Hooke (1665) used the first compound microscope to observe the cells (
cork) .
Source: http://historymicrobio.files.wordpress.com/2012/07/robert-hooke.jpg?w=252&h=300,
http://blogs.scientificamerican.com/history-of-geology/files/2013/07/HOOKE_1665_Micrographia_Cell.jpg
Anton Van Leeuwenhoek improved the lens system. Using the improved lens, he observed a
number of moving structures in a drop of pond water, which he called ‘ an i ma l cul e s’.
Similarly, Nehemiah Grew studied the sections of plant tissues and concluded that all the
tissues consist of cells.
A brief historical account of the landmark researches is given in the table.
Table: History of Cell Biology
Source: Author
Year Name of the Scientist Contribution
1590 Janssen Invented the compound
microscope, which combines
two lenses for greater
magnification.
1665 Robert Hooke Published Micrographia, in
which he describes and
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