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In DNA the linkages between differentnitrogenous bases are:    [NEET Kar. 2013]
  • a)
    peptide linkage
  • b)
    phosphate linkage
  • c)
    H-bonding
  • d)
    glycosidic linkage
Correct answer is option 'C'. Can you explain this answer?
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Verified Answer
In DNA the linkages between differentnitrogenous bases are: [NEET Kar...
The base pairs of the two strands of DNA
are linked together through H-bonds.
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In DNA the linkages between differentnitrogenous bases are: [NEET Kar...


Explanation:

H-bonding:
- In DNA, the linkages between different nitrogenous bases are primarily due to hydrogen bonding.
- Hydrogen bonding occurs between specific pairs of nitrogenous bases: adenine (A) pairs with thymine (T) via two hydrogen bonds, and guanine (G) pairs with cytosine (C) via three hydrogen bonds.
- These hydrogen bonds provide the specificity needed for base pairing in the DNA double helix structure.

Peptide linkage, Phosphate linkage, and Glycosidic linkage:
- Peptide linkage is formed between amino acids in proteins, not between nitrogenous bases in DNA.
- Phosphate linkage refers to the phosphodiester bonds that connect the sugar-phosphate backbone of DNA, not the nitrogenous bases.
- Glycosidic linkage is the bond between the sugar and the nitrogenous base in nucleotides, not the linkage between different nitrogenous bases.

Therefore, the correct answer is option 'C' - H-bonding, as hydrogen bonding is responsible for the specific pairing of nitrogenous bases in DNA.
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Read the passage given below and answer the following questions:EVIDENCE FOR THE FIBROUS NATURE OF DNAThe basic chemical formula of DNA is now well established. As shown in Figure 1 it consists of a very long chain, the backbone of which is made up of alternate sugar and phosphate groups, joined together in regular 3’ 5’ phosphate di-ester linkages. To each sugar is attached a nitrogenous base, only four different kinds of which are commonly found in DNA. Two of these---adenine and guanine--- are purines, and the other two thymine and cytosine-are pyrimidines. A fifth base, 5-methyl cytosine, occurs in smaller amounts in certain organisms, and a sixth, 5-hydroxy-methyl-cytosine, is found instead of cytosine in the T even phages. It should be noted that the chain is unbranched, a consequence of the regular internucleotide linkage. On the other hand the sequence of the different nucleotides is, as far as can be ascertained,completely irregular. Thus, DNA has some features which are regular, and some which are irregular. A similar conception of the DNA molecule as a long thin fiber is obtained from physicochemical analysis involving sedimentation, diffusion, light scattering, and viscosity measurements. These techniques indicate that DNA is a very asymmetrical structure approximately 20 A wide and many thousands of angstroms long. Estimates of its molecular weight currently center between 5 X106 and X107 (approximately 3 X104 nucleotides). Surprisingly each of these measurements tend to suggest that the DNA is relatively rigid, a puzzling finding in view of the large number of single bonds (5 per nucleotid e) in the phosphate-sugar back bone. Recently these indirect inferences have been confirmed by electron microscopy.Q. DNA molecule has ___________ internucleotide linkage and __________ sequence of the different nucleotides

In DNA the linkages between differentnitrogenous bases are: [NEET Kar. 2013]a)peptide linkageb)phosphate linkagec)H-bondingd)glycosidic linkageCorrect answer is option 'C'. Can you explain this answer?
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