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A scientist working at enzymes manufacturing firm created a modified enzyme with application for blood brain barrier(BBB) crossing capabilities to deliver a conjugated drug. Although the composition of new formation was kept secret by company, someone from the company gave a clue that at least three successive amino acids at the external surface of proteins were replaced with one type of aromatic amino acid. Can you predict which of the following replacements were made in the protein?
  • a)
    K453F, L446F, N600F   
  • b)
    N453Y, Q553Y, D345Y
  • c)
    T673W, L678W, K600W
  • d)
    N563W, T636W, K316W
Correct answer is option 'A'. Can you explain this answer?
Verified Answer
A scientist working at enzymes manufacturing firm created a modified e...
Abilities of phenyalanine is highest to cross BBB, hence substitution of few amino acids with F will help.
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A scientist working at enzymes manufacturing firm created a modified enzyme with application for blood brain barrier(BBB) crossing capabilities to deliver a conjugated drug. Although the composition of new formation was kept secret by company, someone from the company gave a clue that at least three successive amino acids at the external surface of proteins were replaced with one type of aromatic amino acid. Can you predict which of the following replacements were made in the protein?a)K453F, L446F, N600Fb)N453Y, Q553Y, D345Yc)T673W, L678W, K600Wd)N563W, T636W, K316WCorrect answer is option 'A'. Can you explain this answer?
Question Description
A scientist working at enzymes manufacturing firm created a modified enzyme with application for blood brain barrier(BBB) crossing capabilities to deliver a conjugated drug. Although the composition of new formation was kept secret by company, someone from the company gave a clue that at least three successive amino acids at the external surface of proteins were replaced with one type of aromatic amino acid. Can you predict which of the following replacements were made in the protein?a)K453F, L446F, N600Fb)N453Y, Q553Y, D345Yc)T673W, L678W, K600Wd)N563W, T636W, K316WCorrect answer is option 'A'. Can you explain this answer? for IIT JAM 2024 is part of IIT JAM preparation. The Question and answers have been prepared according to the IIT JAM exam syllabus. Information about A scientist working at enzymes manufacturing firm created a modified enzyme with application for blood brain barrier(BBB) crossing capabilities to deliver a conjugated drug. Although the composition of new formation was kept secret by company, someone from the company gave a clue that at least three successive amino acids at the external surface of proteins were replaced with one type of aromatic amino acid. Can you predict which of the following replacements were made in the protein?a)K453F, L446F, N600Fb)N453Y, Q553Y, D345Yc)T673W, L678W, K600Wd)N563W, T636W, K316WCorrect answer is option 'A'. Can you explain this answer? covers all topics & solutions for IIT JAM 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for A scientist working at enzymes manufacturing firm created a modified enzyme with application for blood brain barrier(BBB) crossing capabilities to deliver a conjugated drug. Although the composition of new formation was kept secret by company, someone from the company gave a clue that at least three successive amino acids at the external surface of proteins were replaced with one type of aromatic amino acid. Can you predict which of the following replacements were made in the protein?a)K453F, L446F, N600Fb)N453Y, Q553Y, D345Yc)T673W, L678W, K600Wd)N563W, T636W, K316WCorrect answer is option 'A'. Can you explain this answer?.
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