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Which of the following statement is/are true
  • a)
    Malonyl CoA inhibits carnitine acyl transferase I [CAT-I]
  • b)
    Net gain of two ATP occurs if glucose is converted into ethanol
  • c)
    In gluconeogenesis, pyruvate is converted directly into phosphoenol pyruvate
  • d)
    Gluconeogenesis takes place only in liver
Correct answer is option 'A,B'. Can you explain this answer?
Verified Answer
Which of the following statement is/are truea)Malonyl CoA inhibits car...
Statement (a) is correct.
Acetyl CoA is converted into malonyl CoA by acetyl CoA carboxylase enzyme during fatty acid biosynthesis. Malonyl CoA so formed inhibits carnitine acyl transferase I (CAT-I), thereby preventing transport of fatty acids into mitochondria, hence inhibiting oxidation of fatty acids.
Statement (b) is correct. Net gain of two ATP occurs if glucose is converted into ethanol because NADH formed during the process of glycolysis is used in converting pyruvate to ethanol.
Statement (c) is incorrect. Pyruvate is not converted directly into phosphoenol pyruvate. Pyruvate is first converted into oxaloacetate by pyruvate carboxylase. Oxaloacetate is then converted into phosphoenolpyruvate [PEP] by PEP carboxykinase.
Statement (d) is incorrect
Gluconeogenesis occurs both in liver and kidney. Glucose 6 phosphatase enzyme of gluconeogenesis is found on the lumenal side of endoplasmic reticulum of both hepatocytes and renal / kidney cells.    
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Which of the following statement is/are truea)Malonyl CoA inhibits carnitine acyl transferase I [CAT-I]b)Net gain of two ATP occurs if glucose is converted into ethanolc)In gluconeogenesis, pyruvate is converted directly into phosphoenol pyruvated)Gluconeogenesis takes place only in liverCorrect answer is option 'A,B'. Can you explain this answer?
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Which of the following statement is/are truea)Malonyl CoA inhibits carnitine acyl transferase I [CAT-I]b)Net gain of two ATP occurs if glucose is converted into ethanolc)In gluconeogenesis, pyruvate is converted directly into phosphoenol pyruvated)Gluconeogenesis takes place only in liverCorrect answer is option 'A,B'. Can you explain this answer? for IIT JAM 2024 is part of IIT JAM preparation. The Question and answers have been prepared according to the IIT JAM exam syllabus. Information about Which of the following statement is/are truea)Malonyl CoA inhibits carnitine acyl transferase I [CAT-I]b)Net gain of two ATP occurs if glucose is converted into ethanolc)In gluconeogenesis, pyruvate is converted directly into phosphoenol pyruvated)Gluconeogenesis takes place only in liverCorrect answer is option 'A,B'. Can you explain this answer? covers all topics & solutions for IIT JAM 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Which of the following statement is/are truea)Malonyl CoA inhibits carnitine acyl transferase I [CAT-I]b)Net gain of two ATP occurs if glucose is converted into ethanolc)In gluconeogenesis, pyruvate is converted directly into phosphoenol pyruvated)Gluconeogenesis takes place only in liverCorrect answer is option 'A,B'. Can you explain this answer?.
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