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Amino acids residue in a peptide that is most likely to behave as both acid and base at the physiological pH is
  • a)
    Histidine
  • b)
    Isoleucine
  • c)
    Phenylalanine
  • d)
    Tyrosine
Correct answer is option 'A'. Can you explain this answer?
Verified Answer
Amino acids residue in a peptide that is most likely to behave as both...
The ability to act as both acid and base at the physiological pH depends upon pKR of the side chain of amino acid. pKR of histidine is close to physiological pH. Thus it is most likely to act as acid as well as base or proton donor as well as proton acceptor.
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Amino acids residue in a peptide that is most likely to behave as both acid and base at the physiological pH isa)Histidineb)Isoleucinec)Phenylalanined)TyrosineCorrect answer is option 'A'. Can you explain this answer?
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