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Which of the following is the true orientation for purine and pyrimidine in B-DNA when, Watson crick pairing is known to exist
  • a)
    Syn for purine and anti for pyrimidine
  • b)
    Anti for both purine and pyrimidine
  • c)
    Anti for purine and Syn for pyrimidine
  • d)
    Syn for both purine and pyrimidine
Correct answer is option 'B'. Can you explain this answer?
Verified Answer
Which of the following is the true orientation for purine and pyrimidi...
Glycosyl bond conformation in A and B form of DNA is ‘Anti’, whereas in Z form of DNA, it is Anti for pyrimidines and syn for purines.
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Most Upvoted Answer
Which of the following is the true orientation for purine and pyrimidi...
The true orientation for purine and pyrimidine in B-DNA when Watson-Crick pairing is known to exist is anti for both purine and pyrimidine.

Explanation:
B-DNA is the most common and stable form of DNA. It is a right-handed double helix structure in which the two strands are antiparallel and held together by hydrogen bonds. The bases in DNA can be categorized into two types: purines (adenine and guanine) and pyrimidines (cytosine and thymine/uracil).

Watson-Crick pairing:
Watson-Crick pairing refers to the specific base pairing interactions between the purine and pyrimidine bases. Adenine (A) always pairs with thymine (T) through two hydrogen bonds, while guanine (G) always pairs with cytosine (C) through three hydrogen bonds. This complementary base pairing allows for the accurate replication and transmission of genetic information.

Orientations of purine and pyrimidine:
The orientation of the bases in DNA can be either "anti" or "syn" depending on the rotation of the glycosidic bond. In the anti conformation, the base is rotated away from the sugar moiety, while in the syn conformation, the base is rotated towards the sugar moiety.

Correct orientation:
In B-DNA, the correct orientation for both purine and pyrimidine bases is anti. This means that the purine and pyrimidine bases are rotated away from the sugar moiety. The anti conformation allows for optimal hydrogen bonding and stacking interactions between the bases, contributing to the stability of the DNA double helix.

Significance:
The anti orientation of the bases in B-DNA is crucial for maintaining the correct geometry and stability of the double helix structure. The specific Watson-Crick base pairing between A-T and G-C relies on the anti orientation to form the appropriate hydrogen bonds and maintain the proper distance between the base pairs.

Conclusion:
In summary, the true orientation for purine and pyrimidine in B-DNA when Watson-Crick pairing is known to exist is anti for both purine and pyrimidine. This orientation allows for the formation of stable base pairs and the accurate transmission of genetic information.
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Which of the following is the true orientation for purine and pyrimidine in B-DNA when, Watson crick pairing is known to exista)Syn for purine and anti for pyrimidineb)Anti for both purine and pyrimidinec)Anti for purine and Syn for pyrimidined)Syn for both purine and pyrimidineCorrect answer is option 'B'. Can you explain this answer?
Question Description
Which of the following is the true orientation for purine and pyrimidine in B-DNA when, Watson crick pairing is known to exista)Syn for purine and anti for pyrimidineb)Anti for both purine and pyrimidinec)Anti for purine and Syn for pyrimidined)Syn for both purine and pyrimidineCorrect answer is option 'B'. Can you explain this answer? for IIT JAM 2024 is part of IIT JAM preparation. The Question and answers have been prepared according to the IIT JAM exam syllabus. Information about Which of the following is the true orientation for purine and pyrimidine in B-DNA when, Watson crick pairing is known to exista)Syn for purine and anti for pyrimidineb)Anti for both purine and pyrimidinec)Anti for purine and Syn for pyrimidined)Syn for both purine and pyrimidineCorrect answer is option 'B'. Can you explain this answer? covers all topics & solutions for IIT JAM 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Which of the following is the true orientation for purine and pyrimidine in B-DNA when, Watson crick pairing is known to exista)Syn for purine and anti for pyrimidineb)Anti for both purine and pyrimidinec)Anti for purine and Syn for pyrimidined)Syn for both purine and pyrimidineCorrect answer is option 'B'. Can you explain this answer?.
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