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Understanding the Reaction of Glucose with Acetic Anhydride
When glucose reacts with acetic anhydride, it undergoes acetylation, where the hydroxyl (–OH) groups on the glucose molecule are replaced with acetate (–OCOCH3) groups.
Structure of Glucose
- Glucose is a hexose sugar with six carbon atoms.
- It contains five hydroxyl groups (–OH) and one aldehyde group (–CHO).
Acetylation Process
- In the presence of acetic anhydride, each hydroxyl group can be acetylated.
- The reaction typically leads to the formation of an ester bond between the hydroxyl group and the acetic anhydride.
Number of Acetylation Sites
- Glucose has five hydroxyl groups available for acetylation.
- In addition to these, the aldehyde group can also be converted into an acetate, leading to an additional acetylation.
Formation of Penta-acetate
- Since all five hydroxyl groups can react with acetic anhydride, and the aldehyde group can also be acetylated, glucose can form a total of six acetate groups.
- This results in the formation of a fully acetylated glucose compound known as penta-acetate.
Conclusion
- The correct product formed from the reaction of glucose with acetic anhydride is penta-acetate, which accounts for the acetylation of all hydroxyl and the aldehyde functional groups.
- Hence, the correct answer is option 'C', penta-acetate.