GABA (Gamma-aminobutyric acid) is an inhibitory neurotransmitter in the central nervous system, meaning it reduces the activity of neurons. When GABA is released at the synapse area between two neurons, it has specific effects on the postsynaptic neuron. The correct answer is option 'C' - Hyperpolarization of neuron. Let's further explain this answer in detail:

1. Role of GABA:
GABA acts as an inhibitory neurotransmitter in the brain, meaning it reduces the likelihood of the postsynaptic neuron firing an action potential. It plays a crucial role in regulating the excitability of neurons and maintaining the balance between excitation and inhibition in the brain.

2. Opening of GABA receptors:
When GABA is released into the synaptic cleft, it binds to specific receptors called GABA receptors on the postsynaptic neuron. These receptors are ion channels that can open or close in response to the binding of GABA.

3. Hyperpolarization of the neuron:
When GABA binds to its receptors on the postsynaptic neuron, it opens chloride ion channels. This allows the influx of negatively charged chloride ions into the neuron, leading to an increase in its membrane potential. This increase in membrane potential makes the neuron more negative than its resting state, resulting in hyperpolarization.

4. Inhibition of action potential:
Hyperpolarization caused by GABA inhibits the generation of an action potential in the postsynaptic neuron. It raises the threshold for firing an action potential, making it more difficult for the neuron to reach the necessary depolarization level to initiate an action potential.

5. Effects on neuronal activity:
By hyperpolarizing the postsynaptic neuron, GABA reduces its excitability and inhibits the transmission of signals to downstream neurons. This helps to prevent excessive neural activity and maintain a balance between excitation and inhibition in the brain.

In summary, when GABA is released at the synapse area, it binds to its receptors on the postsynaptic neuron, leading to the opening of chloride ion channels and subsequent hyperpolarization of the neuron. This inhibits the generation of an action potential and reduces the excitability of the neuron. Hence, the correct answer is option 'C' - Hyperpolarization of neuron.

The neurotransmitter at inhibitory synapses hyperpolarizes the postsynaptic membrane. For example, gamma-aminobutyric acid (GABA). Binding of GABA to the receptors increases the influx of chloride (Cl) ions into the postsynaptic cell and efflux potassium (K+) ions decreasing its membrane potential and thus inhibiting it.