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Which one of the following is true in breast cancer cells that involve the BRCA 1 gene?
  • a)
    Mutated cells are unable to divide because of increased expression of the BRCA 1 gene
  • b)
    Mutated cells fail to reach the G1-S checkpoint
  • c)
    Mutated cells have an abnormal number of endosomes
  • d)
    Mutated cells lose their G2-M cell cycle checkpoint
Correct answer is option 'D'. Can you explain this answer?
Verified Answer
Which one of the following is true in breast cancer cells that involve...
Mutations in the BRCA 1 gene, a breast tumor supressor gene, are the major cause of breast cancer. In most breast cancers involving this gene, deoxyribonucleic acid synthesis proceeds, indicating that the G1-S checkpoint is not affected; however, the mutated cells cannot control the transition between G2 and M. Moreover, the mutated cells have abnormal centrosome numbers, and their nuclear division does not proceed normally, leading to aneuploidy and genetic instability of the daughter cells.
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Which one of the following is true in breast cancer cells that involve the BRCA 1 gene?a)Mutated cells are unable to divide because of increased expression of the BRCA 1 geneb)Mutated cells fail to reach the G1-S checkpointc)Mutated cells have an abnormal number of endosomesd)Mutated cells lose their G2-M cell cycle checkpointCorrect answer is option 'D'. Can you explain this answer?
Question Description
Which one of the following is true in breast cancer cells that involve the BRCA 1 gene?a)Mutated cells are unable to divide because of increased expression of the BRCA 1 geneb)Mutated cells fail to reach the G1-S checkpointc)Mutated cells have an abnormal number of endosomesd)Mutated cells lose their G2-M cell cycle checkpointCorrect answer is option 'D'. Can you explain this answer? for IIT JAM 2024 is part of IIT JAM preparation. The Question and answers have been prepared according to the IIT JAM exam syllabus. Information about Which one of the following is true in breast cancer cells that involve the BRCA 1 gene?a)Mutated cells are unable to divide because of increased expression of the BRCA 1 geneb)Mutated cells fail to reach the G1-S checkpointc)Mutated cells have an abnormal number of endosomesd)Mutated cells lose their G2-M cell cycle checkpointCorrect answer is option 'D'. Can you explain this answer? covers all topics & solutions for IIT JAM 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Which one of the following is true in breast cancer cells that involve the BRCA 1 gene?a)Mutated cells are unable to divide because of increased expression of the BRCA 1 geneb)Mutated cells fail to reach the G1-S checkpointc)Mutated cells have an abnormal number of endosomesd)Mutated cells lose their G2-M cell cycle checkpointCorrect answer is option 'D'. Can you explain this answer?.
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