Which of the following is not matched during cell apoptosis eventa)Mit...
Apoptosis is characterized by
• decrease in size; plasma mebrane remains intact
• energy dependent, reversible process
• release of cyt-C from mitochondria
• caspases are required for completion of this process
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Which of the following is not matched during cell apoptosis eventa)Mit...
Explanation:
Apoptosis is a programmed cell death process that occurs in multicellular organisms. It plays a crucial role in various physiological processes such as tissue development, immune response, and elimination of damaged cells.
During apoptosis, several events occur that ultimately lead to the death and removal of the cell. Let's analyze each option and determine which one is not matched during cell apoptosis.
a) Mitochondria are involved:
During apoptosis, mitochondria play a central role. They release specific proteins such as cytochrome c into the cytoplasm, which triggers a cascade of events leading to cell death. These proteins activate caspases, a group of enzymes that orchestrate the dismantling of the cell.
b) Energy-dependent, reversible process:
Apoptosis is an energy-dependent process that requires ATP to carry out various cellular events. However, it is important to note that apoptosis is an irreversible process. Once the cell commits to apoptosis, it cannot be reversed or stopped.
c) Cell increases its size and inflamed:
This statement is incorrect. During apoptosis, the cell undergoes shrinkage, not an increase in size. The cell also undergoes characteristic morphological changes such as condensation of the nucleus, fragmentation of the DNA, and formation of apoptotic bodies. Inflammation is not a characteristic of apoptosis but rather associated with necrosis, a different form of cell death.
d) Caspases are intrinsic to the apoptosis pathway:
Caspases are a family of cysteine proteases that play a central role in apoptosis. They are activated during apoptosis and mediate the cleavage of various cellular substrates, leading to cell death. Therefore, this statement is correct.
Conclusion:
Among the given options, the statement "c) Cell increases its size and inflamed" is not matched during cell apoptosis. Apoptosis is characterized by cell shrinkage and the absence of inflammation.