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Pick the correct statement(s) with respect to the inter-conversion of the topoisomers of a circularlyclosed double stranded DNA.
- a)Only one strand needs to be cut
- b)Both strands have to be cut
- c)No strand needs to be cut
- d)ATP is required for inter-conversion
Correct answer is option 'A,D'. Can you explain this answer?
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Pick the correct statement(s) with respect to the inter-conversion of ...
Correct Answer :- a,d
Explanation : Answer is A & D. only one strand needs to be cut. As it will bring DNA from Positively supercoiled to negative supercoiled. ATP is required for inter-conversion. For Positive to negative supercoiled conditions.
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Pick the correct statement(s) with respect to the inter-conversion of ...
Inter-conversion of topoisomers of circularly closed double-stranded DNA
Introduction:
Topoisomers are different forms of DNA molecules that have the same sequence but differ in their topology. In the case of circularly closed double-stranded DNA, there are different topoisomers that can be inter-converted through certain mechanisms.
Statement A: Only one strand needs to be cut
This statement is correct. Inter-conversion of topoisomers of circularly closed double-stranded DNA can be achieved by cutting only one strand of the DNA molecule. This process is catalyzed by enzymes called topoisomerases. The enzyme breaks one of the DNA strands, allows the other strand to pass through the break, and then reseals the DNA strand. This breakage and resealing of a single strand allow the DNA molecule to change its topology.
Statement D: ATP is required for inter-conversion
This statement is correct. ATP (adenosine triphosphate) is required for the inter-conversion of topoisomers. Topoisomerases are ATP-dependent enzymes, meaning they require ATP as an energy source to carry out the process of inter-conversion. ATP hydrolysis provides the energy necessary for the topoisomerase enzyme to break and reseal the DNA strand.
Explanation:
- The inter-conversion of topoisomers of circularly closed double-stranded DNA involves the action of topoisomerase enzymes.
- These enzymes recognize the DNA molecule and create a transient break in one of the DNA strands.
- The topoisomerase enzyme then allows the other DNA strand to pass through the transient break, changing the topology of the DNA molecule.
- After the strand passage is complete, the topoisomerase reseals the DNA strand, restoring the integrity of the DNA molecule.
- This process requires energy, which is provided by ATP hydrolysis. ATP is converted into ADP (adenosine diphosphate) and inorganic phosphate, releasing energy that drives the inter-conversion reaction.
- The inter-conversion of topoisomers is essential for various biological processes, including DNA replication, transcription, and recombination.
- By changing the topology of the DNA molecule, topoisomerases help to relieve torsional strain and supercoiling, ensuring proper DNA function and stability.
Conclusion:
To inter-convert the topoisomers of circularly closed double-stranded DNA, only one strand needs to be cut, and ATP is required for the process. The action of topoisomerases, ATP-dependent enzymes, allows the DNA molecule to change its topology by breaking and resealing a single strand of the DNA molecule. This process is crucial for DNA function and stability.
Introduction:
Topoisomers are different forms of DNA molecules that have the same sequence but differ in their topology. In the case of circularly closed double-stranded DNA, there are different topoisomers that can be inter-converted through certain mechanisms.
Statement A: Only one strand needs to be cut
This statement is correct. Inter-conversion of topoisomers of circularly closed double-stranded DNA can be achieved by cutting only one strand of the DNA molecule. This process is catalyzed by enzymes called topoisomerases. The enzyme breaks one of the DNA strands, allows the other strand to pass through the break, and then reseals the DNA strand. This breakage and resealing of a single strand allow the DNA molecule to change its topology.
Statement D: ATP is required for inter-conversion
This statement is correct. ATP (adenosine triphosphate) is required for the inter-conversion of topoisomers. Topoisomerases are ATP-dependent enzymes, meaning they require ATP as an energy source to carry out the process of inter-conversion. ATP hydrolysis provides the energy necessary for the topoisomerase enzyme to break and reseal the DNA strand.
Explanation:
- The inter-conversion of topoisomers of circularly closed double-stranded DNA involves the action of topoisomerase enzymes.
- These enzymes recognize the DNA molecule and create a transient break in one of the DNA strands.
- The topoisomerase enzyme then allows the other DNA strand to pass through the transient break, changing the topology of the DNA molecule.
- After the strand passage is complete, the topoisomerase reseals the DNA strand, restoring the integrity of the DNA molecule.
- This process requires energy, which is provided by ATP hydrolysis. ATP is converted into ADP (adenosine diphosphate) and inorganic phosphate, releasing energy that drives the inter-conversion reaction.
- The inter-conversion of topoisomers is essential for various biological processes, including DNA replication, transcription, and recombination.
- By changing the topology of the DNA molecule, topoisomerases help to relieve torsional strain and supercoiling, ensuring proper DNA function and stability.
Conclusion:
To inter-convert the topoisomers of circularly closed double-stranded DNA, only one strand needs to be cut, and ATP is required for the process. The action of topoisomerases, ATP-dependent enzymes, allows the DNA molecule to change its topology by breaking and resealing a single strand of the DNA molecule. This process is crucial for DNA function and stability.
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Pick the correct statement(s) with respect to the inter-conversion of the topoisomers of a circularlyclosed double stranded DNA.a)Only one strand needs to be cutb)Both strands have to be cutc)No strand needs to be cutd)ATP is required for inter-conversionCorrect answer is option 'A,D'. Can you explain this answer?
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Pick the correct statement(s) with respect to the inter-conversion of the topoisomers of a circularlyclosed double stranded DNA.a)Only one strand needs to be cutb)Both strands have to be cutc)No strand needs to be cutd)ATP is required for inter-conversionCorrect answer is option 'A,D'. Can you explain this answer? for IIT JAM 2024 is part of IIT JAM preparation. The Question and answers have been prepared according to the IIT JAM exam syllabus. Information about Pick the correct statement(s) with respect to the inter-conversion of the topoisomers of a circularlyclosed double stranded DNA.a)Only one strand needs to be cutb)Both strands have to be cutc)No strand needs to be cutd)ATP is required for inter-conversionCorrect answer is option 'A,D'. Can you explain this answer? covers all topics & solutions for IIT JAM 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Pick the correct statement(s) with respect to the inter-conversion of the topoisomers of a circularlyclosed double stranded DNA.a)Only one strand needs to be cutb)Both strands have to be cutc)No strand needs to be cutd)ATP is required for inter-conversionCorrect answer is option 'A,D'. Can you explain this answer?.
Pick the correct statement(s) with respect to the inter-conversion of the topoisomers of a circularlyclosed double stranded DNA.a)Only one strand needs to be cutb)Both strands have to be cutc)No strand needs to be cutd)ATP is required for inter-conversionCorrect answer is option 'A,D'. Can you explain this answer? for IIT JAM 2024 is part of IIT JAM preparation. The Question and answers have been prepared according to the IIT JAM exam syllabus. Information about Pick the correct statement(s) with respect to the inter-conversion of the topoisomers of a circularlyclosed double stranded DNA.a)Only one strand needs to be cutb)Both strands have to be cutc)No strand needs to be cutd)ATP is required for inter-conversionCorrect answer is option 'A,D'. Can you explain this answer? covers all topics & solutions for IIT JAM 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Pick the correct statement(s) with respect to the inter-conversion of the topoisomers of a circularlyclosed double stranded DNA.a)Only one strand needs to be cutb)Both strands have to be cutc)No strand needs to be cutd)ATP is required for inter-conversionCorrect answer is option 'A,D'. Can you explain this answer?.
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Pick the correct statement(s) with respect to the inter-conversion of the topoisomers of a circularlyclosed double stranded DNA.a)Only one strand needs to be cutb)Both strands have to be cutc)No strand needs to be cutd)ATP is required for inter-conversionCorrect answer is option 'A,D'. Can you explain this answer?, a detailed solution for Pick the correct statement(s) with respect to the inter-conversion of the topoisomers of a circularlyclosed double stranded DNA.a)Only one strand needs to be cutb)Both strands have to be cutc)No strand needs to be cutd)ATP is required for inter-conversionCorrect answer is option 'A,D'. Can you explain this answer? has been provided alongside types of Pick the correct statement(s) with respect to the inter-conversion of the topoisomers of a circularlyclosed double stranded DNA.a)Only one strand needs to be cutb)Both strands have to be cutc)No strand needs to be cutd)ATP is required for inter-conversionCorrect answer is option 'A,D'. Can you explain this answer? theory, EduRev gives you an
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