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If a genetic disease is transferred from a phenotypically normal but carrier female to only some of the male progeny, the disease is
- a)Autosomal dominant
- b)Autosomal recessive
- c)Sex-linked dominant
- d)Sex-linked recessive
Correct answer is option 'A'. Can you explain this answer?
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If a genetic disease is transferred from a phenotypically normal but c...
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If a genetic disease is transferred from a phenotypically normal but c...
Explanation:
In order to understand why the correct answer is option 'A' (autosomal dominant), it is important to have a basic understanding of genetic inheritance patterns.
Autosomal Dominant Inheritance:
- Autosomal dominant diseases are caused by a mutation in one copy of a gene located on one of the autosomes (non-sex chromosomes).
- A person with an autosomal dominant disorder has a 50% chance of passing the disease-causing allele to each of their children.
- Both males and females can be affected by the disease, and it is equally likely to be passed on to both male and female offspring.
Carrier Female:
- A carrier is an individual who carries a disease-causing allele but does not exhibit any symptoms of the disease.
- In this scenario, the carrier female is phenotypically normal, meaning she does not show any signs of the genetic disease.
Transferring the Disease to Only Some Male Progeny:
- In autosomal dominant inheritance, if a carrier female passes on the disease-causing allele to her offspring, there is a 50% chance that each child will inherit the disease.
- Since the disease is only transferred to some of the male progeny, it indicates that the trait is not sex-linked.
- If the disease were sex-linked, it would more likely affect all male progeny, as males only have one X chromosome and are more susceptible to sex-linked disorders.
Conclusion:
Based on the information provided, it can be concluded that the genetic disease in question follows an autosomal dominant inheritance pattern because it is transferred from a phenotypically normal, carrier female to only some of the male progeny.
In order to understand why the correct answer is option 'A' (autosomal dominant), it is important to have a basic understanding of genetic inheritance patterns.
Autosomal Dominant Inheritance:
- Autosomal dominant diseases are caused by a mutation in one copy of a gene located on one of the autosomes (non-sex chromosomes).
- A person with an autosomal dominant disorder has a 50% chance of passing the disease-causing allele to each of their children.
- Both males and females can be affected by the disease, and it is equally likely to be passed on to both male and female offspring.
Carrier Female:
- A carrier is an individual who carries a disease-causing allele but does not exhibit any symptoms of the disease.
- In this scenario, the carrier female is phenotypically normal, meaning she does not show any signs of the genetic disease.
Transferring the Disease to Only Some Male Progeny:
- In autosomal dominant inheritance, if a carrier female passes on the disease-causing allele to her offspring, there is a 50% chance that each child will inherit the disease.
- Since the disease is only transferred to some of the male progeny, it indicates that the trait is not sex-linked.
- If the disease were sex-linked, it would more likely affect all male progeny, as males only have one X chromosome and are more susceptible to sex-linked disorders.
Conclusion:
Based on the information provided, it can be concluded that the genetic disease in question follows an autosomal dominant inheritance pattern because it is transferred from a phenotypically normal, carrier female to only some of the male progeny.
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If a genetic disease is transferred from a phenotypically normal but carrier female to only some of the male progeny, the disease isa)Autosomal dominantb)Autosomal recessivec)Sex-linked dominantd)Sex-linked recessiveCorrect answer is option 'A'. Can you explain this answer?
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