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How can a female be haemophilic?
  • a)
    Mother is haemophilic and father is normal
  • b)
    Mother is a carrier and father is haemophilic
  • c)
    Both mother and father are carriers
  • d)
    Both mother and father are haemophilic
Correct answer is option 'B'. Can you explain this answer?
Most Upvoted Answer
How can a female be haemophilic?a)Mother is haemophilic and father is ...

Explanation:

Carrier Status:
- Hemophilia is an X-linked recessive genetic disorder, meaning the gene responsible for the disorder is located on the X chromosome.
- Females have two X chromosomes, while males have one X and one Y chromosome.
- A female can be a carrier of hemophilia if she has one normal X chromosome and one X chromosome with the hemophilia gene.
- Carriers do not typically show symptoms of the disorder because they have a normal X chromosome to compensate for the defective one.

Parental Inheritance:
- If the mother is a carrier of the hemophilia gene and the father is unaffected, there is a 50% chance that their daughters will be carriers.
- In this scenario, the female offspring would inherit one X chromosome with the hemophilia gene from the carrier mother.
- Since females have two X chromosomes, they can be carriers of the disorder without exhibiting symptoms.

Conclusion:
- Therefore, a female can be hemophilic if her mother is a carrier of the hemophilia gene and her father is unaffected. The female would inherit the defective X chromosome from her carrier mother and would be a carrier herself.
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Community Answer
How can a female be haemophilic?a)Mother is haemophilic and father is ...
A female can only be haemophilic if her mother is at least a carrier of this disease and her father is haemophilic. But the possibility of a female becoming haemophilic is extremely rare because being haemophilic for the parents at the later stage of life is unviable.
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How can a female be haemophilic?a)Mother is haemophilic and father is normalb)Mother is a carrier and father is haemophilicc)Both mother and father are carriersd)Both mother and father are haemophilicCorrect answer is option 'B'. Can you explain this answer?
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