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Pre-mRNAs Are rapidly bound by snRNPs which carry out dual steps of RNA splicing, that remove the intron and joins the upstream and downstream exons. The following statements describe some facts related to this event.
A. Almost all introns begin with GU and end with AG sequences hence all the GU or AG sequences are spliced out of RNA.
B. U2 RNA recognizes important sequences at the 3' acceptor end of the intron.
C. The spliceosome uses ATP to carry out accurate removal of the intron.
D. An unusual linkage with 2’ OH group of guanosine within the intron form a Lariet structure.
Which of the following combinations is correct:
- a)A only
- b)B and D
- c)C and D
- d)A and D
Correct answer is option 'B'. Can you explain this answer?
Verified Answer
Pre-mRNAs Are rapidly bound by snRNPs which carry out dual steps of RN...
Concept:
- snRNPs participate in pre-mRNA splicing by recognizing the critical sequence elements present in the introns, thereby forming active spliceosomes.
- The recognition is achieved primarily by base-pairing interactions (or nucleotide-nucleotide contact) between snRNAs and pre-mRNA.
- Notably, snRNAs are extensively modified with different RNA modifications, which confer unique properties to the RNAs.
- Researchers have the current knowledge of the mechanisms and functions of snRNA modifications and their biological relevance in the splicing process.
Explanation:
Fig 1: Spliceosome assembly
Spliceosome assembly is a dynamic multi-step process:
- A. Almost all introns begin with GU and end with AG sequences, hence all the GU or AG sequences are spliced out of RNA.
- This statement is incorrect.
- While it is true that many introns begin with a GU sequence at the 5' end and end with an AG sequence at the 3' end, not all GU or AG sequences are spliced out.
- These sequences serve as consensus sequences that help in the recognition of the intron-exon boundaries, but they are not completely spliced out. Instead, they play important roles in the splicing process.
- B. U2 RNA recognizes important sequences at the 3' acceptor end of the intron.
- This statement is correct.
- U2 RNA is part of a small nuclear ribonucleoprotein particle (snRNP) called U2 snRNP.
- U2 snRNP recognizes and binds to the intron-exon boundary at the 3' acceptor site of the intron.
- This interaction is essential for the accurate splicing of the intron.
- C. The spliceosome uses ATP to carry out accurate removal of the intron.
- This statement is incorrect.
- While ATP is involved in various steps of RNA splicing, it is not directly used by the spliceosome for the removal of the intron.
- ATP hydrolysis is required for the assembly, rearrangement, and disassembly of the spliceosome during the splicing process.
- D. An unusual linkage with 2’ OH group of guanosine within the intron forms a Lariat structure.
- This statement is correct.
- During the splicing process, the 2' OH group of an adenosine residue within the intron forms a phosphodiester bond with the 5' end of the intron, resulting in the formation of a lariat structure.
- This lariat structure allows the intron to be excised from the pre-mRNA molecule, and the exons are then joined together to form the mature mRNA.
- Thus, statement B is correct as U2 RNA recognizes important sequences at the 3' acceptor end of the intron. Statement D is also correct as the 2' OH group of guanosine within the intron forms a lariat structure. Statements A and C are incorrect.
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Pre-mRNAs Are rapidly bound by snRNPs which carry out dual steps of RNA splicing, that remove the intron and joins the upstream and downstream exons. The following statements describe some facts related to this event. A. Almost all introns begin with GU and end with AG sequences hence all the GU or AG sequences are spliced out of RNA. B. U2 RNA recognizes important sequences at the 3' acceptor end of the intron. C. The spliceosome uses ATP to carry out accurate removal of the intron. D. An unusual linkage with 2’ OH group of guanosine within the intron form a Lariet structure. Which of the following combinations is correct:a)A onlyb)B and Dc)C and Dd)A and DCorrect answer is option 'B'. Can you explain this answer?
Question Description
Pre-mRNAs Are rapidly bound by snRNPs which carry out dual steps of RNA splicing, that remove the intron and joins the upstream and downstream exons. The following statements describe some facts related to this event. A. Almost all introns begin with GU and end with AG sequences hence all the GU or AG sequences are spliced out of RNA. B. U2 RNA recognizes important sequences at the 3' acceptor end of the intron. C. The spliceosome uses ATP to carry out accurate removal of the intron. D. An unusual linkage with 2’ OH group of guanosine within the intron form a Lariet structure. Which of the following combinations is correct:a)A onlyb)B and Dc)C and Dd)A and DCorrect answer is option 'B'. Can you explain this answer? for Software Development 2025 is part of Software Development preparation. The Question and answers have been prepared according to the Software Development exam syllabus. Information about Pre-mRNAs Are rapidly bound by snRNPs which carry out dual steps of RNA splicing, that remove the intron and joins the upstream and downstream exons. The following statements describe some facts related to this event. A. Almost all introns begin with GU and end with AG sequences hence all the GU or AG sequences are spliced out of RNA. B. U2 RNA recognizes important sequences at the 3' acceptor end of the intron. C. The spliceosome uses ATP to carry out accurate removal of the intron. D. An unusual linkage with 2’ OH group of guanosine within the intron form a Lariet structure. Which of the following combinations is correct:a)A onlyb)B and Dc)C and Dd)A and DCorrect answer is option 'B'. Can you explain this answer? covers all topics & solutions for Software Development 2025 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Pre-mRNAs Are rapidly bound by snRNPs which carry out dual steps of RNA splicing, that remove the intron and joins the upstream and downstream exons. The following statements describe some facts related to this event. A. Almost all introns begin with GU and end with AG sequences hence all the GU or AG sequences are spliced out of RNA. B. U2 RNA recognizes important sequences at the 3' acceptor end of the intron. C. The spliceosome uses ATP to carry out accurate removal of the intron. D. An unusual linkage with 2’ OH group of guanosine within the intron form a Lariet structure. Which of the following combinations is correct:a)A onlyb)B and Dc)C and Dd)A and DCorrect answer is option 'B'. Can you explain this answer?.
Pre-mRNAs Are rapidly bound by snRNPs which carry out dual steps of RNA splicing, that remove the intron and joins the upstream and downstream exons. The following statements describe some facts related to this event. A. Almost all introns begin with GU and end with AG sequences hence all the GU or AG sequences are spliced out of RNA. B. U2 RNA recognizes important sequences at the 3' acceptor end of the intron. C. The spliceosome uses ATP to carry out accurate removal of the intron. D. An unusual linkage with 2’ OH group of guanosine within the intron form a Lariet structure. Which of the following combinations is correct:a)A onlyb)B and Dc)C and Dd)A and DCorrect answer is option 'B'. Can you explain this answer? for Software Development 2025 is part of Software Development preparation. The Question and answers have been prepared according to the Software Development exam syllabus. Information about Pre-mRNAs Are rapidly bound by snRNPs which carry out dual steps of RNA splicing, that remove the intron and joins the upstream and downstream exons. The following statements describe some facts related to this event. A. Almost all introns begin with GU and end with AG sequences hence all the GU or AG sequences are spliced out of RNA. B. U2 RNA recognizes important sequences at the 3' acceptor end of the intron. C. The spliceosome uses ATP to carry out accurate removal of the intron. D. An unusual linkage with 2’ OH group of guanosine within the intron form a Lariet structure. Which of the following combinations is correct:a)A onlyb)B and Dc)C and Dd)A and DCorrect answer is option 'B'. Can you explain this answer? covers all topics & solutions for Software Development 2025 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Pre-mRNAs Are rapidly bound by snRNPs which carry out dual steps of RNA splicing, that remove the intron and joins the upstream and downstream exons. The following statements describe some facts related to this event. A. Almost all introns begin with GU and end with AG sequences hence all the GU or AG sequences are spliced out of RNA. B. U2 RNA recognizes important sequences at the 3' acceptor end of the intron. C. The spliceosome uses ATP to carry out accurate removal of the intron. D. An unusual linkage with 2’ OH group of guanosine within the intron form a Lariet structure. Which of the following combinations is correct:a)A onlyb)B and Dc)C and Dd)A and DCorrect answer is option 'B'. Can you explain this answer?.
Solutions for Pre-mRNAs Are rapidly bound by snRNPs which carry out dual steps of RNA splicing, that remove the intron and joins the upstream and downstream exons. The following statements describe some facts related to this event. A. Almost all introns begin with GU and end with AG sequences hence all the GU or AG sequences are spliced out of RNA. B. U2 RNA recognizes important sequences at the 3' acceptor end of the intron. C. The spliceosome uses ATP to carry out accurate removal of the intron. D. An unusual linkage with 2’ OH group of guanosine within the intron form a Lariet structure. Which of the following combinations is correct:a)A onlyb)B and Dc)C and Dd)A and DCorrect answer is option 'B'. Can you explain this answer? in English & in Hindi are available as part of our courses for Software Development.
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Pre-mRNAs Are rapidly bound by snRNPs which carry out dual steps of RNA splicing, that remove the intron and joins the upstream and downstream exons. The following statements describe some facts related to this event. A. Almost all introns begin with GU and end with AG sequences hence all the GU or AG sequences are spliced out of RNA. B. U2 RNA recognizes important sequences at the 3' acceptor end of the intron. C. The spliceosome uses ATP to carry out accurate removal of the intron. D. An unusual linkage with 2’ OH group of guanosine within the intron form a Lariet structure. Which of the following combinations is correct:a)A onlyb)B and Dc)C and Dd)A and DCorrect answer is option 'B'. Can you explain this answer?, a detailed solution for Pre-mRNAs Are rapidly bound by snRNPs which carry out dual steps of RNA splicing, that remove the intron and joins the upstream and downstream exons. The following statements describe some facts related to this event. A. Almost all introns begin with GU and end with AG sequences hence all the GU or AG sequences are spliced out of RNA. B. U2 RNA recognizes important sequences at the 3' acceptor end of the intron. C. The spliceosome uses ATP to carry out accurate removal of the intron. D. An unusual linkage with 2’ OH group of guanosine within the intron form a Lariet structure. Which of the following combinations is correct:a)A onlyb)B and Dc)C and Dd)A and DCorrect answer is option 'B'. Can you explain this answer? has been provided alongside types of Pre-mRNAs Are rapidly bound by snRNPs which carry out dual steps of RNA splicing, that remove the intron and joins the upstream and downstream exons. The following statements describe some facts related to this event. A. Almost all introns begin with GU and end with AG sequences hence all the GU or AG sequences are spliced out of RNA. B. U2 RNA recognizes important sequences at the 3' acceptor end of the intron. C. The spliceosome uses ATP to carry out accurate removal of the intron. D. An unusual linkage with 2’ OH group of guanosine within the intron form a Lariet structure. Which of the following combinations is correct:a)A onlyb)B and Dc)C and Dd)A and DCorrect answer is option 'B'. Can you explain this answer? theory, EduRev gives you an
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