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A 28-year-old woman, Vimla is being evaluated to find the cause of her urine turning a dark brown color after a recent upper respiratory tract infection. She has been otherwise symptomatic, and her blood pressure has been within normal limits. Urinalysis finds moderate blood present with red cells and red cell casts. Immunofluorescence examination of a renal biopsy reveals deposits of IgA within the mesangium. These clinical findings suggest that her disorder is associated with activation of the alternate complement system. Which of the following serum laboratory findings is the most suggestive of activation of the alternate complement system rather than the classic complement system?
  • a)
    a
  • b)
    b
  • c)
    c
  • d)
    d
  • e)
    e
Correct answer is option 'B'. Can you explain this answer?
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A 28-year-old woman, Vimla is being evaluated to find the cause of her...
Activation of the complement cascade can lead to the local accumulation of C3, detectable through specific histological techniques. If a patient experiences extensive activation of the complement system, serum tests may reveal reduced C3 levels. Specifically, activation of the classical complement pathway results in diminished levels of the early complement components, including C1, C4, and C2. Conversely, activation of the alternative complement pathway lowers C3 levels, while the early factors (C2 and C4) remain at normal levels. A condition linked with the activation of the alternative complement system is IgA nephropathy (Berger’s disease), which is marked by the deposition of IgA in the mesangium of the glomeruli.
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A 28-year-old woman, Vimla is being evaluated to find the cause of her urine turning a dark brown color after a recent upper respiratory tract infection. She has been otherwise symptomatic, and her blood pressure has been within normal limits. Urinalysis finds moderate blood present with red cells and red cell casts. Immunofluorescence examination of a renal biopsy reveals deposits of IgA within the mesangium. These clinical findings suggest that her disorder is associated with activation of the alternate complement system. Which of the following serum laboratory findings is the most suggestive of activation of the alternate complement system rather than the classic complement system?a)ab)bc)cd)de)eCorrect answer is option 'B'. Can you explain this answer? for NEET PG 2026 is part of NEET PG preparation. The Question and answers have been prepared according to the NEET PG exam syllabus. Information about A 28-year-old woman, Vimla is being evaluated to find the cause of her urine turning a dark brown color after a recent upper respiratory tract infection. She has been otherwise symptomatic, and her blood pressure has been within normal limits. Urinalysis finds moderate blood present with red cells and red cell casts. Immunofluorescence examination of a renal biopsy reveals deposits of IgA within the mesangium. These clinical findings suggest that her disorder is associated with activation of the alternate complement system. Which of the following serum laboratory findings is the most suggestive of activation of the alternate complement system rather than the classic complement system?a)ab)bc)cd)de)eCorrect answer is option 'B'. Can you explain this answer? covers all topics & solutions for NEET PG 2026 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for A 28-year-old woman, Vimla is being evaluated to find the cause of her urine turning a dark brown color after a recent upper respiratory tract infection. She has been otherwise symptomatic, and her blood pressure has been within normal limits. Urinalysis finds moderate blood present with red cells and red cell casts. Immunofluorescence examination of a renal biopsy reveals deposits of IgA within the mesangium. These clinical findings suggest that her disorder is associated with activation of the alternate complement system. Which of the following serum laboratory findings is the most suggestive of activation of the alternate complement system rather than the classic complement system?a)ab)bc)cd)de)eCorrect answer is option 'B'. Can you explain this answer?.
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