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Which type of substance would face difficulty to pass through the cell membrane? [NEET 2022 Phase 2]
- a)Substance soluble in lipids
- b)Substance with hydrophobic moiety
- c)Substance with hydrophilic moiety
- d)All substance irrespective of hydrophobic and hydrophilic moiety
Correct answer is option 'C'. Can you explain this answer?
Most Upvoted Answer
Which type of substance would face difficulty to pass through the cell...
Substances that have a hydrophilic moiety find it difficult to pass through the plasma membrane; thus, their movement has to be facilitated.
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Which type of substance would face difficulty to pass through the cell...
Understanding Cell Membrane Permeability
The cell membrane, or plasma membrane, is primarily composed of a phospholipid bilayer, which serves as a barrier to regulate what enters and exits the cell. The nature of a substance largely determines its ability to permeate this membrane.
Substance Solubility in Lipids
- Substances that are lipid-soluble can easily pass through the cell membrane.
- The hydrophobic (water-repelling) tails of phospholipids allow lipid-soluble substances to integrate and diffuse through the membrane.
Hydrophobic Moieties
- Substances with hydrophobic properties also tend to pass through the cell membrane more easily.
- These substances can interact favorably with the lipid bilayer, facilitating their movement across the membrane.
Hydrophilic Moieties
- In contrast, substances with hydrophilic properties are polar or charged, making it difficult for them to cross the hydrophobic lipid bilayer.
- Water-soluble substances, ions, and polar molecules struggle to diffuse through the membrane without assistance.
Conclusion
- The correct answer is option 'C' because hydrophilic substances face significant difficulty when attempting to pass through the cell membrane.
- They require specific transport mechanisms, such as channel proteins or carrier proteins, to facilitate their movement across the membrane.
Thus, understanding the nature of substances in relation to the cell membrane's structure is crucial for comprehending their transport mechanisms.
The cell membrane, or plasma membrane, is primarily composed of a phospholipid bilayer, which serves as a barrier to regulate what enters and exits the cell. The nature of a substance largely determines its ability to permeate this membrane.
Substance Solubility in Lipids
- Substances that are lipid-soluble can easily pass through the cell membrane.
- The hydrophobic (water-repelling) tails of phospholipids allow lipid-soluble substances to integrate and diffuse through the membrane.
Hydrophobic Moieties
- Substances with hydrophobic properties also tend to pass through the cell membrane more easily.
- These substances can interact favorably with the lipid bilayer, facilitating their movement across the membrane.
Hydrophilic Moieties
- In contrast, substances with hydrophilic properties are polar or charged, making it difficult for them to cross the hydrophobic lipid bilayer.
- Water-soluble substances, ions, and polar molecules struggle to diffuse through the membrane without assistance.
Conclusion
- The correct answer is option 'C' because hydrophilic substances face significant difficulty when attempting to pass through the cell membrane.
- They require specific transport mechanisms, such as channel proteins or carrier proteins, to facilitate their movement across the membrane.
Thus, understanding the nature of substances in relation to the cell membrane's structure is crucial for comprehending their transport mechanisms.
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