NEET Exam > NEET Questions > Which of the following statements about the w... Start Learning for Free
Which of the following statements about the wobble hypothesis is correct?
- a)The first base of the codon can pair with multiple bases of the anticodon
- b)The third base of the codon can pair with multiple bases of the anticodon
- c)The second base of the codon shows wobble pairing
- d)All three bases of the codon show wobble pairing
Correct answer is option 'B'. Can you explain this answer?
Most Upvoted Answer
Which of the following statements about the wobble hypothesis is corre...
The correct answer is Option B - The third base of the codon can pair with multiple bases of the anticodon
According to the wobble hypothesis proposed by Francis Crick, flexible or non-standard pairing occurs at the third base of the codon (the 3' end of the codon) with the first base of the anticodon (the 5' end of the anticodon).
The first two positions of the codon pair by strict Watson-Crick base pairing, which enforces exact complementary geometry and prevents wobble at those positions.
This wobble at the third codon base explains the degeneracy of the genetic code, allowing fewer distinct tRNA species to recognise multiple codons that differ only in the third base.
For example, when inosine is present at the 5' position of an anticodon, it can pair with A, U or C, enabling a single tRNA to read several synonymous codons that vary at the third position.
Therefore, statements claiming wobble at the first or second codon bases, or claiming that all three bases wobble, are incorrect because only the third base of the codon exhibits this flexible pairing behaviour.
Free Test
FREE
| Start Free Test |
Community Answer
Which of the following statements about the wobble hypothesis is corre...
Understanding the Wobble Hypothesis
The wobble hypothesis is a key concept in molecular biology that explains how tRNA can recognize multiple codons for the same amino acid. Here's a detailed look at the statement and why option 'B' is correct.
Wobble Position in Codons
- The "wobble" refers specifically to the third base of the codon.
- This base can pair with more than one base in the corresponding tRNA anticodon.
Why Option 'B' is Correct
- The third base of the codon is less stringent in its pairing rules, allowing for flexibility.
- This flexibility means that for certain tRNA molecules, they can recognize codons that differ by the third base, leading to the phenomenon of wobble pairing.
Examples of Wobble Pairing
- For instance, the codon CCG can be recognized by a tRNA with the anticodon GGC or GGU, demonstrating the ability of the third base to "wobble."
- This reduces the number of tRNA molecules required for translation, as one tRNA can pair with multiple codons.
Incorrect Statements in Other Options
- Option A: The first base of the codon does not exhibit wobble pairing; it must match precisely with the corresponding base in the anticodon.
- Option C: The second base of the codon also shows strict pairing rules and does not participate in wobbling.
- Option D: Not all three bases show wobble pairing, as only the third base does.
Conclusion
In summary, the wobble hypothesis highlights the flexibility of the third base in codon-anticodon interactions, making option 'B' the correct answer. This principle is crucial for understanding genetic coding and protein synthesis in cells.
The wobble hypothesis is a key concept in molecular biology that explains how tRNA can recognize multiple codons for the same amino acid. Here's a detailed look at the statement and why option 'B' is correct.
Wobble Position in Codons
- The "wobble" refers specifically to the third base of the codon.
- This base can pair with more than one base in the corresponding tRNA anticodon.
Why Option 'B' is Correct
- The third base of the codon is less stringent in its pairing rules, allowing for flexibility.
- This flexibility means that for certain tRNA molecules, they can recognize codons that differ by the third base, leading to the phenomenon of wobble pairing.
Examples of Wobble Pairing
- For instance, the codon CCG can be recognized by a tRNA with the anticodon GGC or GGU, demonstrating the ability of the third base to "wobble."
- This reduces the number of tRNA molecules required for translation, as one tRNA can pair with multiple codons.
Incorrect Statements in Other Options
- Option A: The first base of the codon does not exhibit wobble pairing; it must match precisely with the corresponding base in the anticodon.
- Option C: The second base of the codon also shows strict pairing rules and does not participate in wobbling.
- Option D: Not all three bases show wobble pairing, as only the third base does.
Conclusion
In summary, the wobble hypothesis highlights the flexibility of the third base in codon-anticodon interactions, making option 'B' the correct answer. This principle is crucial for understanding genetic coding and protein synthesis in cells.
 | Explore Courses for NEET exam |  |
Top Courses for NEETView all
Top Courses for NEET
Question Description
Which of the following statements about the wobble hypothesis is correct?a)The first base of the codon can pair with multiple bases of the anticodonb)The third base of the codon can pair with multiple bases of the anticodonc)The second base of the codon shows wobble pairingd)All three bases of the codon show wobble pairingCorrect answer is option 'B'. Can you explain this answer? for NEET 2026 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about Which of the following statements about the wobble hypothesis is correct?a)The first base of the codon can pair with multiple bases of the anticodonb)The third base of the codon can pair with multiple bases of the anticodonc)The second base of the codon shows wobble pairingd)All three bases of the codon show wobble pairingCorrect answer is option 'B'. Can you explain this answer? covers all topics & solutions for NEET 2026 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Which of the following statements about the wobble hypothesis is correct?a)The first base of the codon can pair with multiple bases of the anticodonb)The third base of the codon can pair with multiple bases of the anticodonc)The second base of the codon shows wobble pairingd)All three bases of the codon show wobble pairingCorrect answer is option 'B'. Can you explain this answer?.
Which of the following statements about the wobble hypothesis is correct?a)The first base of the codon can pair with multiple bases of the anticodonb)The third base of the codon can pair with multiple bases of the anticodonc)The second base of the codon shows wobble pairingd)All three bases of the codon show wobble pairingCorrect answer is option 'B'. Can you explain this answer? for NEET 2026 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about Which of the following statements about the wobble hypothesis is correct?a)The first base of the codon can pair with multiple bases of the anticodonb)The third base of the codon can pair with multiple bases of the anticodonc)The second base of the codon shows wobble pairingd)All three bases of the codon show wobble pairingCorrect answer is option 'B'. Can you explain this answer? covers all topics & solutions for NEET 2026 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Which of the following statements about the wobble hypothesis is correct?a)The first base of the codon can pair with multiple bases of the anticodonb)The third base of the codon can pair with multiple bases of the anticodonc)The second base of the codon shows wobble pairingd)All three bases of the codon show wobble pairingCorrect answer is option 'B'. Can you explain this answer?.
Solutions for Which of the following statements about the wobble hypothesis is correct?a)The first base of the codon can pair with multiple bases of the anticodonb)The third base of the codon can pair with multiple bases of the anticodonc)The second base of the codon shows wobble pairingd)All three bases of the codon show wobble pairingCorrect answer is option 'B'. Can you explain this answer? in English & in Hindi are available as part of our courses for NEET. Download more important topics, notes, lectures and mock test series for NEET Exam by signing up for free.
Here you can find the meaning of Which of the following statements about the wobble hypothesis is correct?a)The first base of the codon can pair with multiple bases of the anticodonb)The third base of the codon can pair with multiple bases of the anticodonc)The second base of the codon shows wobble pairingd)All three bases of the codon show wobble pairingCorrect answer is option 'B'. Can you explain this answer? defined & explained in the simplest way possible. Besides giving the explanation of Which of the following statements about the wobble hypothesis is correct?a)The first base of the codon can pair with multiple bases of the anticodonb)The third base of the codon can pair with multiple bases of the anticodonc)The second base of the codon shows wobble pairingd)All three bases of the codon show wobble pairingCorrect answer is option 'B'. Can you explain this answer?, a detailed solution for Which of the following statements about the wobble hypothesis is correct?a)The first base of the codon can pair with multiple bases of the anticodonb)The third base of the codon can pair with multiple bases of the anticodonc)The second base of the codon shows wobble pairingd)All three bases of the codon show wobble pairingCorrect answer is option 'B'. Can you explain this answer? has been provided alongside types of Which of the following statements about the wobble hypothesis is correct?a)The first base of the codon can pair with multiple bases of the anticodonb)The third base of the codon can pair with multiple bases of the anticodonc)The second base of the codon shows wobble pairingd)All three bases of the codon show wobble pairingCorrect answer is option 'B'. Can you explain this answer? theory, EduRev gives you an ample number of questions to practice Which of the following statements about the wobble hypothesis is correct?a)The first base of the codon can pair with multiple bases of the anticodonb)The third base of the codon can pair with multiple bases of the anticodonc)The second base of the codon shows wobble pairingd)All three bases of the codon show wobble pairingCorrect answer is option 'B'. Can you explain this answer? tests, examples and also practice NEET tests.
| Explore Courses for NEET exam | |
Top Courses for NEET
Explore Courses
Signup for Free!
Signup to see your scores go up within 7 days! Learn & Practice with 1000+ FREE Notes, Videos & Tests.
