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Which of the following statements about antigen- antibody (Ag- Ab) complexes is (are) TRUE?
  • a)
    Hydrogen bonds and van der Waals forces participate in Ag- Ab interactions
  • b)
    Ionic bonds and hydrophobic bonds participate in Ag- Ab interactions
  • c)
    The combined strengths of all interactions between a single antigen binding site on an antibody and a single epitope is called avidity
  • d)
    Antibody elicited by one antigen can cross react with an unrelated antigen
Correct answer is option 'A,B,D'. Can you explain this answer?
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Which of the following statements about antigen- antibody (Ag- Ab) com...
Introduction:
Antigen-antibody (Ag-Ab) complexes are formed when an antibody binds to an antigen. These complexes play a crucial role in the immune response and are involved in various biological processes. Several forces and interactions contribute to the formation and stability of Ag-Ab complexes.

Hydrogen bonds and van der Waals forces participate in Ag-Ab interactions:
Hydrogen bonds and van der Waals forces are two types of non-covalent interactions that participate in Ag-Ab interactions. Hydrogen bonds are formed between the antigen and antibody through the attraction between a hydrogen atom and a highly electronegative atom (such as oxygen or nitrogen). These bonds contribute to the specificity and stability of the Ag-Ab complex. Van der Waals forces, on the other hand, are weak attractive forces between molecules due to temporary shifts in electron density. These forces also contribute to the stability of the Ag-Ab complex.

Ionic bonds and hydrophobic bonds participate in Ag-Ab interactions:
Ionic bonds are formed between oppositely charged ions and can participate in Ag-Ab interactions. If the antigen or antibody contains charged groups, they can interact through ionic bonds. Hydrophobic bonds, also known as hydrophobic interactions, occur between nonpolar molecules in an aqueous environment. Hydrophobic regions on the antigen or antibody can interact with each other, contributing to the stability of the Ag-Ab complex.

The combined strengths of all interactions between a single antigen binding site on an antibody and a single epitope is called avidity:
Avidity refers to the combined strength of all interactions between a single antigen binding site on an antibody and a single epitope. It takes into account multiple interactions, including hydrogen bonds, van der Waals forces, ionic bonds, and hydrophobic bonds. Avidity is an important parameter to assess the overall strength of the Ag-Ab complex.

Antibody elicited by one antigen can cross-react with an unrelated antigen:
Antibodies can sometimes exhibit cross-reactivity, which means they can bind to antigens other than the one they were originally elicited by. This occurs when the unrelated antigen shares structural similarities with the original antigen, leading to binding of the antibody. Cross-reactivity can have both positive and negative implications in the immune response.

In conclusion, the statements A, B, and D are true. Hydrogen bonds and van der Waals forces participate in Ag-Ab interactions, ionic bonds and hydrophobic bonds can also be involved, and antibodies can elicit a cross-reactive response with unrelated antigens. These interactions and phenomena contribute to the formation, stability, and specificity of Ag-Ab complexes.
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Which of the following statements about antigen- antibody (Ag- Ab) complexes is (are) TRUE?a)Hydrogen bonds and van der Waals forces participate in Ag- Ab interactionsb)Ionic bonds and hydrophobic bonds participate in Ag- Ab interactionsc)The combined strengths of all interactions between a single antigen binding site on an antibody and a single epitope is called avidityd)Antibody elicited by one antigen can cross react with an unrelated antigenCorrect answer is option 'A,B,D'. Can you explain this answer?
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Which of the following statements about antigen- antibody (Ag- Ab) complexes is (are) TRUE?a)Hydrogen bonds and van der Waals forces participate in Ag- Ab interactionsb)Ionic bonds and hydrophobic bonds participate in Ag- Ab interactionsc)The combined strengths of all interactions between a single antigen binding site on an antibody and a single epitope is called avidityd)Antibody elicited by one antigen can cross react with an unrelated antigenCorrect answer is option 'A,B,D'. Can you explain this answer? for IIT JAM 2024 is part of IIT JAM preparation. The Question and answers have been prepared according to the IIT JAM exam syllabus. Information about Which of the following statements about antigen- antibody (Ag- Ab) complexes is (are) TRUE?a)Hydrogen bonds and van der Waals forces participate in Ag- Ab interactionsb)Ionic bonds and hydrophobic bonds participate in Ag- Ab interactionsc)The combined strengths of all interactions between a single antigen binding site on an antibody and a single epitope is called avidityd)Antibody elicited by one antigen can cross react with an unrelated antigenCorrect answer is option 'A,B,D'. Can you explain this answer? covers all topics & solutions for IIT JAM 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Which of the following statements about antigen- antibody (Ag- Ab) complexes is (are) TRUE?a)Hydrogen bonds and van der Waals forces participate in Ag- Ab interactionsb)Ionic bonds and hydrophobic bonds participate in Ag- Ab interactionsc)The combined strengths of all interactions between a single antigen binding site on an antibody and a single epitope is called avidityd)Antibody elicited by one antigen can cross react with an unrelated antigenCorrect answer is option 'A,B,D'. Can you explain this answer?.
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