RCs: 21 to 30 Questions for CAT with Answers PDF

Directions: Read the given passage carefully and answer the questions that follow:
Several genes have been acknowledged that appear to play a role in the advance of obesity. These genes are often identified through mouse models for obesity, such as a pure–breeding strain of obese mice called Rotund. The behavior of Rotund mice includes increased food consumption and body weight, and decreased body temperature and activity. When injected with blood from normal animals, Rotund mice exhibit a momentary decrease in food intake. This information suggests that a secreted factor that signals satiety exists, turning off the desire for food in normal animals when energy reserves in stock tissue are sufficient.
When the gene responsible for the Rotund behavior was identified, it was found to encode a protein secreted from adipocytes in normal mice. This protein was termed the rotund protein. Injection of purified rotund protein from wild–type mice into Rotund mice induces a decrease in food intake, an increase in body temperature, an increase in activity, and a decrease over several weeks in the ratio of energy stock tissue to skeletal muscle. Control injections lacking rotund protein did not produce these changes.
Also, injection of rotund protein into normal mice does not alter weight or other parameters of mouse physiology, indicating that the weight loss in Rotund mice is not caused by toxicity of the protein to the animal. Although the research on the rotund protein and on its effects on obesity is in its development phase, scientists hope that what they learn from these experiments with mice will shed some light on the ongoing research on human obesity.
Q1: Which of the following can be most strongly concluded from the passage?
(a) Humans possess similar proteins to those of Rotund mice.
(b) There are heart failure problems in Rotund mice.
(c) Rotund proteins from wild–type mice and pure–breeding mice do not have the identical impact.
(d) Rotund protein does not have create any toxic effects on the Rotund mice.
Ans: (c)
Sol: This choice is supported by the text, since Injection of purified rotund protein from wild–type mice into Rotund mice induces a decrease in food intake…skeletal muscle. If it is seen that the wild–type protein changes how the Rotund mice behaves, then it must be different from the protein that Rotund mice produce themselves.

Q2: The author of the passage would possibly agree with which of the following sentences?
(a) This study on rotund proteins, by itself, might not be sufficient enough to solve the human obesity problem.
(b) Scientists will be able to make much progress on human obesity because of their findings on rotund proteins.
(c) The study is expected to result in a repercussion from consumer groups and civil rights unions.
(d) There are some faults in the way the experiment has been designed.
Ans: (a)
Sol: The author’s statements throughout the passage are tentative. Phrases such as appear to play a role and this information suggests, as well as that scientists hope…will shed some light show that the author may not believe that this research will necessarily be a complete solution. The injection of purified rotund protein from wild–type mice into Rotund mice which induced a decrease in food intake is an external means of changing behavior.

Q3: All of the following choices regarding the pure–breeding Rotund mice behavior are true EXCEPT:
(a) These mice tend to possess colder bodies as compared to the non–obese Rotund mice’s bodies.
(b) The consumption of daily food is higher than that of other mice.
(c) The obese Rotund mice roam in their environment less than do other mice.
(d) Rotund mice experience more problems associated with foot pain usually related with obesity.
Ans: (d)
Sol: While it might be tempting due to outside knowledge to suppose that obese mice suffer from foot pain because obese people often do, this choice is outside knowledge. The relation between foot pain and obese mice is not offered in  the text.