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Hypertension-JNC 8 Guidelines

Hypertension - Guidelines | Medical Science Optional Notes for UPSC

Hypertension - Guidelines

Hypertension - Guidelines | Medical Science Optional Notes for UPSC

The AHA/ACC ASCVD (Atherosclerotic Cardiovascular Disease) 2013 Risk Calculator assesses the 10-year risk of heart disease or stroke. It considers parameters such as age, sex, race, history of smoking, diabetes, hypertension treatment, and values of total cholesterol, HDL, and systolic blood pressure (SBP) in its calculation.

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What factors does the AHA/ACC ASCVD Risk Calculator consider when assessing the 10-year risk of heart disease or stroke?
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Non-Pharmacological Interventions

Hypertension - Guidelines | Medical Science Optional Notes for UPSC

Pharmacological Interventions

1. Specific Recommendations:

  • For the non-black population (including those with diabetes), initial treatment should encompass a thiazide-type diuretic, calcium channel blocker (CCB), angiotensin-converting enzyme inhibitor (ACE-I), or angiotensin receptor blocker (ARB).
  • In the general African American population (including those with diabetes), the preferred initial treatment is a thiazide-type diuretic or CCB.
  • Among adults with chronic kidney disease, the recommended initial (or add-on) treatment involves an ACE inhibitor or ARB to enhance kidney outcomes.

2. Initiation of Treatment and Follow-up:

  • Consider the number of antihypertensives.
    • For newly diagnosed hypertension with blood pressure (BP) below 150/90 mm Hg, initiate therapy with one primary antihypertensive.
    • For newly diagnosed hypertension with BP above 150/90 mm Hg, initiate therapy with two primary antihypertensives.
  • Reassess within one month of initiating or modifying pharmacological therapy.
    • If the treatment goal is not achieved with one drug, consider increasing the dose of the initial drug or adding a second drug.
    • If the treatment goal cannot be reached with two drugs, add a third drug.
    • Evaluate for secondary causes of hypertension.
    • If blood pressure is controlled, reassess after 3-6 months and subsequently on an annual basis.
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FAQs on Hypertension - Guidelines - Medical Science Optional Notes for UPSC

1. What are the non-pharmacological interventions recommended in the JNC 8 guidelines for hypertension?
Ans. The JNC 8 guidelines recommend several non-pharmacological interventions for hypertension, including lifestyle modifications such as weight loss, adopting a healthy diet (such as the DASH diet), reducing sodium intake, increasing physical activity, limiting alcohol consumption, and quitting smoking.
2. Are non-pharmacological interventions effective in managing hypertension?
Ans. Yes, non-pharmacological interventions have been shown to be effective in managing hypertension. Lifestyle modifications, such as weight loss and adopting a healthy diet, can significantly lower blood pressure and reduce the risk of cardiovascular events.
3. What are the pharmacological interventions recommended in the JNC 8 guidelines for hypertension?
Ans. The JNC 8 guidelines recommend several classes of antihypertensive medications for pharmacological interventions, including thiazide diuretics, calcium channel blockers, angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), and beta-blockers. The choice of medication depends on various factors, including the patient's age, race, and comorbidities.
4. Should non-pharmacological interventions be tried before starting pharmacological interventions for hypertension?
Ans. Yes, non-pharmacological interventions should be tried before starting pharmacological interventions for hypertension, unless the patient has stage 2 hypertension or a high cardiovascular risk. Lifestyle modifications can often help lower blood pressure and reduce the need for medication.
5. Can non-pharmacological interventions alone be sufficient in managing hypertension?
Ans. In some cases, non-pharmacological interventions alone can be sufficient in managing hypertension, particularly in patients with prehypertension or stage 1 hypertension. However, in more severe cases or when lifestyle modifications are not enough, pharmacological interventions may also be necessary to achieve optimal blood pressure control. It is important to work with a healthcare professional to determine the most appropriate treatment plan.
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