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Thyroid gland-Gross Anatomy

The thyroid gland is comprised of two lobes, namely the right and left lobes. Each lobe has dimensions of approximately 5cm x 2.5cm x 2.5cm, extending from the middle of the thyroid cartilage to the Fourth/Fifth tracheal ring. These lobes are interconnected by an isthmus measuring 1.2cm x 1.2071cm in the lower parts. Notably, the size of the lobes tends to be larger in females during pregnancy and menstruation.

Thyroid Gland: Miscellaneous | Medical Science Optional Notes for UPSC

The gland is enveloped by a pseudo or false capsule created by the Pretracheal layer of the deep cervical fascia, while the authentic capsule is shaped by the peripheral condensation of the gland's connective tissue. To prevent hemorrhage during surgical procedures, the thyroid is excised along with the genuine capsule.

Thyroid Gland: Miscellaneous | Medical Science Optional Notes for UPSC

The False capsule, known as the Suspensory Ligament of Berry, is constituted by the Pretracheal layer of the deep cervical fascia. While it is thin along the posterior border of the lobes, it becomes thicker on the inner surface of the gland, creating the Suspensory Ligament of Berry. This ligament connects the thyroid lobe to the cricoid cartilage.

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Relations of lobes of the thyroid

Thyroid Gland: Miscellaneous | Medical Science Optional Notes for UPSC

Relations of Isthmus of the thyroid

Thyroid Gland: Miscellaneous | Medical Science Optional Notes for UPSC

Thyroid Gland: Miscellaneous | Medical Science Optional Notes for UPSC

Thyroid gland-Blood supply

Arterial supply

The thyroid gland receives arterial supply from the superior and inferior thyroid arteries.

Superior Thyroid Artery:

  • A branch of the external carotid artery.
  • It descends in front of the external laryngeal nerve.
  • The artery pierces the Pretracheal fascia to reach the upper pole of the trachea.
  • It subsequently divides into anterior and posterior branches.
  • The anterior branch courses along the anterior border of the thyroid, following the isthmus.
  • The posterior branch travels along the posterior border, forming an anastomosis with a branch of the inferior thyroid artery.

Thyroid Gland: Miscellaneous | Medical Science Optional Notes for UPSC

Inferior thyroid artery

  • It stems from the thyrocervical trunk.
  • Following its origin, it ascends and moves medially before descending to reach the lower pole of the gland.
  • In its terminal segment, it has proximity to the recurrent laryngeal nerve.

Thyroid Gland: Miscellaneous | Medical Science Optional Notes for UPSC

Note: The superior thyroid artery provides blood to the upper one-third of the thyroid lobes and the upper half of the isthmus, while the inferior thyroid artery supplies the remaining portion of the gland.
In approximately 3% of the population, there is an extra artery known as the thyroidea ima artery, originating from either the brachiocephalic trunk or the arch of the aorta.

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Which artery supplies the upper one-third of the thyroid lobes and the upper half of the isthmus?
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Venous supply

  • The superior thyroid vein originates in the upper pole of the gland and empties into the internal jugular vein.
  • The middle thyroid vein originates near the middle of the gland and drains into the internal jugular vein.
  • The inferior thyroid vein, originating near the lower border of the isthmus, drains into the left brachiocephalic vein.
  • The fourth thyroid vein of Kochee, situated between the middle and inferior veins, drains into the internal jugular vein.

Thyroid gland-Lymphatic drainage

Lymphatic vessels of the thyroid connect with the tracheal plexus and extend to the prelaryngeal nodes located just above the thyroid isthmus, as well as to the pretracheal and paratracheal nodes. Some may also direct drainage into the brachiocephalic nodes associated with the thymus in the superior mediastinum. On the lateral aspect, vessels along the superior thyroid veins drain the gland into the deep cervical nodes. Additionally, thyroid lymphatics may establish a direct drainage path to the thoracic duct without an intervening node.

Thyroid gland - Repeats

  • Discuss the development of thyroid gland and its blood supply (2002).
  • Describe the thyroid gland under the following headings (2013)
    i. Lobes
    ii. Relations
    iii. Surgical anatomy
The document Thyroid Gland: Miscellaneous | Medical Science Optional Notes for UPSC is a part of the UPSC Course Medical Science Optional Notes for UPSC.
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FAQs on Thyroid Gland: Miscellaneous - Medical Science Optional Notes for UPSC

1. What is the gross anatomy of the thyroid gland?
Ans. The thyroid gland is located in the front of the neck, just below the Adam's apple. It consists of two lobes connected by a narrow isthmus. The lobes are shaped like butterflies or the letter "H" and are situated on either side of the trachea. The gland is composed of numerous follicles filled with colloid, which is a gel-like substance containing thyroid hormones.
2. What is the blood supply of the thyroid gland?
Ans. The thyroid gland receives its blood supply from two pairs of arteries: the superior thyroid arteries and the inferior thyroid arteries. The superior thyroid arteries arise from the external carotid arteries, while the inferior thyroid arteries arise from the thyrocervical trunk, a branch of the subclavian arteries. These arteries provide oxygenated blood to the thyroid gland, allowing it to function properly.
3. How does the thyroid gland drain lymphatically?
Ans. The lymphatic drainage of the thyroid gland occurs through a network of lymphatic vessels. The lymphatic vessels from the superior part of the gland drain into the deep cervical lymph nodes, located along the internal jugular vein. The lymphatic vessels from the inferior part of the gland drain into the pretracheal and paratracheal lymph nodes. From these lymph nodes, the lymphatic fluid eventually reaches the thoracic duct and is returned to the bloodstream.
4. What are some miscellaneous facts about the thyroid gland?
Ans. The thyroid gland is responsible for producing and secreting thyroid hormones, which regulate the body's metabolism and energy levels. It is also involved in the growth and development of various tissues and organs. Conditions such as hypothyroidism and hyperthyroidism can occur when the thyroid gland is underactive or overactive, respectively. The function of the thyroid gland can be assessed through blood tests that measure the levels of thyroid-stimulating hormone (TSH), thyroxine (T4), and triiodothyronine (T3). Additionally, the thyroid gland is susceptible to diseases such as goiter, thyroid nodules, and thyroid cancer.
5. How can thyroid gland disorders be treated?
Ans. The treatment of thyroid gland disorders depends on the specific condition. For hypothyroidism, synthetic thyroid hormone replacement therapy is typically prescribed to restore hormone levels. Hyperthyroidism can be treated with medications that reduce thyroid hormone production or with radioactive iodine therapy to destroy overactive thyroid cells. Surgical removal of part or all of the thyroid gland may be necessary in certain cases, such as thyroid cancer or large goiters. Regular monitoring and follow-up with a healthcare provider are crucial for managing thyroid gland disorders effectively.
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