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Vaccination & Immunisation - NEET Biology Class 12 Free MCQ Test with solutions


MCQ Practice Test & Solutions: Test: Vaccination & Immunisation (15 Questions)

You can prepare effectively for NEET Biology Class 12 with this dedicated MCQ Practice Test (available with solutions) on the important topic of "Test: Vaccination & Immunisation". These 15 questions have been designed by the experts with the latest curriculum of NEET 2026, to help you master the concept.

Test Highlights:

  • - Format: Multiple Choice Questions (MCQ)
  • - Duration: 10 minutes
  • - Number of Questions: 15

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Test: Vaccination & Immunisation - Question 1

Innate immunity fails to protect an individual when

Detailed Solution: Question 1

Innate immunity is non-specific and relies on barriers. If a pathogen bypasses these, innate immunity fails.

Test: Vaccination & Immunisation - Question 2

Which cells will most likely show an immediate response during the first few hours of a viral infection?

Detailed Solution: Question 2

NK cells are part of innate immunity and destroy infected cells quickly before specific immunity is activated.

Test: Vaccination & Immunisation - Question 3

Assertion: Secondary immune response appears more rapid and intense than primary response.
Reason: Memory B-cells formed during the primary response quickly differentiate into plasma cells upon second exposure.

Detailed Solution: Question 3

Memory cells lead to a rapid, stronger secondary response.

Test: Vaccination & Immunisation - Question 4

Which immunoglobulin would be most useful in diagnosing an ongoing acute infection?

Detailed Solution: Question 4

IgM is produced first in primary immune responses and indicates recent infection.

Test: Vaccination & Immunisation - Question 5

A child received antibodies intravenously after a snakebite. Later, he also receives a vaccine. Which statement distinguishes the two treatments?

Detailed Solution: Question 5

Injected antibodies act immediately and do not produce memory; vaccines induce active immunity.

Test: Vaccination & Immunisation - Question 6

Match the items of Column I with Column II.

Detailed Solution: Question 6

Interferons are antiviral, mast cells release histamine, Peyer’s patches are intestinal lymphoid tissues, and thymus matures T-cells.

Test: Vaccination & Immunisation - Question 7

A person with severe thymus degeneration in adulthood is most likely to show

Detailed Solution: Question 7

Thymus governs T-cell maturation; degeneration reduces T-cell mediated immunity.

Test: Vaccination & Immunisation - Question 8

Which scenario demonstrates humoral immunity?

Detailed Solution: Question 8

Humoral immunity involves antibody production by plasma cells.

Test: Vaccination & Immunisation - Question 9

A patient develops watery eyes and sneezing immediately upon entering a dusty room. Which immunoglobulin and cell type are primarily responsible?

Detailed Solution: Question 9

Allergy reactions involve IgE binding to mast cells, which release histamine.

Test: Vaccination & Immunisation - Question 10

Which one is correct regarding auto-immune diseases?

Detailed Solution: Question 10

Autoimmunity results from self-reactive lymphocytes attacking body tissues.

Test: Vaccination & Immunisation - Question 11

A person exposed to the hepatitis B antigen shows a rapid antibody spike within two days. What does this indicate?

Detailed Solution: Question 11

Rapid and intense response is characteristic of secondary exposure.

Test: Vaccination & Immunisation - Question 12

Which structure acts as a filtration site for blood-borne pathogens?

Detailed Solution: Question 12

The spleen filters blood and traps pathogens.

Test: Vaccination & Immunisation - Question 13

MALT is most important for protection against pathogens entering through

Detailed Solution: Question 13

MALT is present in mucosal linings of respiratory, digestive and urogenital tracts.

Test: Vaccination & Immunisation - Question 14

Which feature distinguishes innate immunity from acquired immunity?

Detailed Solution: Question 14

Answer: C

Innate immunity does not produce a stronger or faster response on subsequent exposures because it lacks immunological memory, so lack of memory is the distinguishing feature.

Innate responses are non-specific and act immediately, whereas acquired (adaptive) immunity is specific to particular pathogens and develops memory after exposure.

The option Presence of antibodies is a feature of adaptive immunity (antibodies are produced by B cells), so it does not describe innate immunity.

The option Involvement of T-cells refers to adaptive cellular responses; T-cells are components of adaptive immunity, not a defining feature of innate immunity.

Therefore, only option C correctly identifies a feature that distinguishes innate immunity from acquired immunity.

Test: Vaccination & Immunisation - Question 15

During organ transplantation, rejection occurs primarily due to

Detailed Solution: Question 15

Cell-mediated immunity (T-cells) recognises non-self tissues and initiates graft rejection.

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