RRB Staff Nurse Mock Test - 5 - RRB NTPC/ASM/CA/TA MCQ

Chaperone proteins, or molecular chaperones, are proteins that assist others to fold properly during or after synthesis, to refold after partial denaturation, and to translocate to the cellular locales at which they reside and function.

Isoniazid: reduces folate activity is the wrong mechanism of action for the listed drug/toxin. Mechanism of action — The antimicrobial activity of INH is selective for mycobacteria, likely due to its ability to inhibit mycolic acid synthesis, which interferes with cell wall synthesis, thereby producing a bactericidal effect. Isoniazid (INH) was the first synthesized drug that mediated bactericidal killing of the bacterium Mycobacterium tuberculosis, a major clinical breakthrough.

For fecal occult blood testing at home, the stool specimens cannot be contaminated with water or urine. The fecal occult blood test (FOBT) is a diagnostic test to assess for occult blood in the stool. This test has commonly been used for colorectal cancer screening, especially in developed nations. When used correctly for screening, this testing modality has established associations with decreased morbidity and mortality. When performing at home, the stool should be collected in a dry, clean container.

β-ketoacyl ACP synthase condenses acyl and malonyl groups.

Malonyl co-A ACP transferase transfers malonyl group from co-A to ACP.

Acyl carrier protein carries acetyl groups in thio-ester linkage.

Acetyl co-A ACP transacylase transfers acyl group from co-A to cys residue of KS.

Dihydrotestosterone is also known as stanolone. It is an endogenous androgen sex steroid and hormone. Wilson7 hypothesized that it was dihydrotestosterone (DHT), the highly biologically active metabolite converted from testosterone in the prostate by the isoenzymes 5α-reductase type 1 (5AR1) and type 2 (5AR2), which was responsible for activating the AR.

The nurse makes sure of the availability of atropine sulfate (Atropine).

The patient is experiencing signs of a cholinergic crisis. When administering edrophonium chloride, have emergency resuscitation equipment on hand and atropine sulfate available.

A patient tells the nurse that she is practicing fertility awareness. The nurse tells the patient that the "unsafe period" can range from seven days before and seven days after ovulation.

According to the family planning method of contraception, the period in which conception can occur and one should refrain from intercourse is up to 7 days before and 7 days after ovulation. Some references show that sperm can live for up to five to seven days inside the female reproductive system. An unfertilized egg can live from between 12-24 hours. This greatly increases the window in which conception can occur.

Straining on defecation requires the person to hold the breath while bearing down. This maneuver increases the intrathoracic and intracranial pressures, which can precipitate dysrhythmias, brain attack, and respiratory difficulties; all of these can be life threatening. Strain at stool causes blood pressure rise, which can trigger cardiovascular events such as congestive heart failure, arrhythmia, acute coronary disease, and aortic dissection.

A nurse giving a shot of vitamin K to a 30-day-old baby. The target area vastus lateralis would be best suited. The drugs are injected into the widest part of the vastus lateral thigh muscle, the muscle located on the lateral part of the thigh.

Vitamin K helps the blood to clot and prevents serious bleeding. In newborns, vitamin K injections can prevent a now rare, but potentially fatal, bleeding disorder called 'vitamin K deficiency bleeding' (VKDB), also known as 'haemorrhagic disease of the newborn' (HDN).

Alveoli are tiny air sacs in the lungs where the exchange of oxygen and carbon dioxide takes place.

It is a hollow cup-shaped cavity where the gaseous exchange takes place. In other words, Alveoli facilitates gaseous exchange of oxygen and carbon dioxide between inhaled air and the bloodstream. A typical pair of human lungs contain approximately 480 million alveoli.

The medium of anaphylactic shock is histamine.

• Anaphylaxis is caused by an overreaction of your immune system to an allergen or something your body is allergic to. This involves hives, swelling and sudden drop in blood pressure, and sometimes shock.
• Anaphylactic shock is a rare but severe allergic reaction that can be deadly if you don't treat it right away. It's most often caused by an allergy to food, insect bites, or certain medications.
• With anaphylaxis, histamine concentrations in the blood increase rapidly.
• In anaphylaxis histamine, H1-receptor stimulation can mediate vascular permeability, smooth muscle contraction, and tachycardia, whereas H2-receptor stimulation can mediate mucus secretion. Stimulation of both receptors can mediate vasodilation and reduce peripheral vascular resistance.

Antoni van Leeuwenhoek, a Delft cloth merchant, is considered the father of microbiology. He discovered the invisible world of microorganisms using homemade microscopes.

Subluxation is the most common form of DDH. DDH is a group of congenital abnormalities of the hip joints, which includes subluxation, dislocation, and preluxation.

Fetal tachycardia is caused due to all of the given factors except Severe Fetal hypoxia.

A fetal tachycardia can be associated with several maternal, as well as fetal conditions, including:

Maternal:

• Maternal hyperthyroidism
• Maternal medications
• Maternal anaemia
• Maternal tachycardia (eg systemic infection)

Fetal:

• In uterine infection
• In utero hypoxia
• Fetal anaemia
• Chromosomal anomalie

Frog has shown the ability to breathe through its skin. Apart from it earthworm can also breathe through its skin. The frog has three respiratory surfaces on its body that it uses to exchange gas with the surroundings: the skin, in the lungs and on the lining of the mouth. While completely submerged all of the frog's respiration takes place through the skin.

In Middle mediastinum compartment of the thoracic cavity are the heart, the phrenic nerve and the pericardium present.

Acceleration type of fetal heart rate characteristic has occurred.

The other name of glycolysis is EMP pathway.

The scheme of glycolysis was given by Gustav Embden, Otto Meyerhof, and J. Parnas, and is often referred to as the EMP pathway. In anaerobic organisms, it is the only process in respiration. Glycolysis occurs in the cytoplasm of the cell and is present in all living organisms. In this process, glucose undergoes partial oxidation to form two molecules of pyruvic acid.

All of the above are serious signs and symptoms of pre-eclampsia.

• Pre-eclampsia is gestational hypertension with proteinuria.
• Blood pressure is 140/90 mmHg.
• It starts after the 20th week in non-hypertensive pregnant women.
• It is also characterized by edema in the ankles.
• Severe headache and trouble seeing.
  
• Increased proteinuria.
  
• Sudden swelling of the feet, ankles, face and hands.

The nurse will need to assess the patient’s performance of clean intermittent self catheterization (CISC) for a client with Kock pouch urinary diversion.

In Kock pouch, a pouch or reservoir is fashioned out of the terminal ileum with a valve mechanism at its exit to the skin surface. This allows storage of the liquid bowel contents in an expandable container with no leakage of stool or gas and therefore no skin problems. There is no need for appliances or bags, no embarrassment from the involuntary noise and smell of flatus through the ileostomy. The stoma is created flush and within the bikini line. The patient catheterizes the pouch an average of three times a day.

A patient's family does not know the patient's end-of-life care preferences, but assumes that they know what is best for the patient under the circumstances. This assumption reflects Paternalism.

It is the system in which a government or an employer protects the people who are governed or employed by providing them with what they need, but does not give them any responsibility or freedom of choice.

A defensive reaction intended to neutralize, control or eliminate the offending agent and to prepare the site for repair is called inflammation.

• Inflammation is a defensive reaction intended to neutralize, control, or eliminate the offending agent and to prepare the site for repair.
• The innate immune system is the body's first line of defense against germs entering the body.

Rational analog: It is a force in a linear motion that is torque.

Formula to calculate rational analog:

Where  is the torque,  is the radius of the rotatory motion, and  is the force applied.

• Force is necessary for a body to do translational motion.
• Similarly, it is torque that is required to rotate a body.
• If the net torque applied to the body about the axis of rotation is zero, then the body does not rotate.

So, the rotational analogue of force is torque.

There are three approaches in overcoming the bioavailability problems these are the pharmaceutic approach, pharmacokinetic approach, and biologic approach. The pharmaceutic approach involves modification of formulation, manufacturing processes. The pharmacokinetic approach is in which the pharmacokinetics of the drug is altered by modifying its chemical structure. The biologic approach is where the route of administration can be changed.

A red blood cell transfusion is used to correct anemia in patients in which the low red blood cell count must be rapidly corrected. Red blood cell transfusions may be given to patients with severe iron-deficiency anemia who are actively bleeding or have significant symptoms such as chest pain, shortness of breath, or weakness. Transfusions are given to replace deficient red blood cells and will not completely correct the iron deficiency.

The Ajanta caves are situated at a distance of about 100 km north of Aurangabad in Maharashtra.

Ajanta has twenty-nine caves.

It has four chaitya caves datable to the earlier phase, i.e., the second and the first century BCE (Cave Nos. 10 and 9) and the later phase, i.e., the fifth century CE (Cave Nos. 19 and 26).

The Hinayana sect of Buddhism started the excavation of caves in Ajanta.

When educating parents regarding known antecedent infections in acute glomerulonephritis, nurse should cover Impetigo.

Impetigo, a bacterial infection of the skin, may be caused by streptococci and may precede acute glomerulonephritis. Although most streptococcal infections do not cause acute glomerulonephritis, when they do, a latent period of 10 to 14 days occurs between the infection, usually of the skin (impetigo) or upper respiratory tract, and the onset of clinical manifestations.

Dakshin Gangotri was a research base station set up by Indian scientists in Antarctica. It was administered by the Indian Antarctic Program under the National Centre for Antarctic and Ocean Research (NCAOR). It started functioning on 26th January 1984. It is located around 2500 km from the South Pole and was used for research about climate change and ocean topography.

The least possible Venn Diagram for the given data is:

Conclusions:

I. Some wallets are envelopes → False (It is possible but not definite, therefore it is false)

II. No wallet is an envelope → False (It is possible but not definite, therefore it is false)

III. No bag is an envelope → False (As some bags are envelope therefore it is false.)

None of the conclusions are true but conclusions I and II form a complementary pair.

Thus, either conclusion I or II follows.

Given,

Option (A) follows.

Option (B) does not follows.

Option (C) does not follows.

Option (D) does not follows.