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Immunology (Lecture 17) - Complement System Video Lecture - MBBS

FAQs on Immunology (Lecture 17) - Complement System Video Lecture - MBBS

1. What is the role of the complement system in the immune response?

Ans. The complement system is a group of proteins in the blood that plays a crucial role in the immune response. It helps in the recognition and destruction of pathogens, such as bacteria and viruses, by promoting inflammation, opsonization (enhancing phagocytosis), and direct lysis of the pathogens.

2. How is the complement system activated?

Ans. The complement system can be activated through three pathways: the classical pathway, the lectin pathway, and the alternative pathway. The classical pathway is initiated by the binding of antibodies to the pathogens. The lectin pathway is activated when lectins bind to specific sugar molecules on the pathogens' surface. The alternative pathway is continuously activated at a low level and can be triggered by certain molecules on the pathogens' surface.

3. What are the main functions of the complement system?

Ans. The main functions of the complement system are to enhance the immune response by promoting inflammation, opsonization (coating pathogens to enhance phagocytosis), and direct lysis of pathogens. Additionally, the complement system helps in clearing immune complexes and initiating the adaptive immune response.

4. How does the complement system promote inflammation?

Ans. The complement system promotes inflammation by attracting immune cells, such as neutrophils and macrophages, to the site of infection or tissue damage. This is achieved through the release of chemotactic factors, which act as chemical signals to recruit immune cells. Inflammation helps in containing and eliminating pathogens, as well as initiating tissue repair.

5. What happens when the complement system is overactivated?

Ans. When the complement system is overactivated, it can lead to harmful effects on the body. Excessive complement activation can cause tissue damage, inflammation, and even autoimmune diseases. Therefore, the complement system is tightly regulated to prevent overactivation and maintain immune homeostasis.

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Nov 23, 2024 Last updated

Immunology (Lecture 17) - Complement System for MBBS2024 is part of MBBS preparation. The notes and questions for Immunology (Lecture 17) - Complement System have been prepared according to the MBBS exam syllabus. Information about Immunology (Lecture 17) - Complement System covers all important topics for MBBS2024 Exam. Find important definitions, questions, notes, meanings, examples, exercises and tests below for Immunology (Lecture 17) - Complement System.

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