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Pyruvate Oxidation Video Lecture | Biology Class 11 - NEET

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FAQs on Pyruvate Oxidation Video Lecture - Biology Class 11 - NEET

1. What is pyruvate oxidation?
Ans. Pyruvate oxidation is a metabolic pathway that occurs in the mitochondria of cells. It is the process by which pyruvate, a product of glycolysis, is converted into acetyl-CoA, releasing carbon dioxide and generating NADH in the process. Acetyl-CoA then enters the citric acid cycle for further energy production.
2. How does pyruvate oxidation contribute to energy production?
Ans. Pyruvate oxidation plays a crucial role in energy production. During pyruvate oxidation, acetyl-CoA is produced, which enters the citric acid cycle. In the citric acid cycle, acetyl-CoA undergoes further reactions, leading to the production of high-energy molecules such as NADH and FADH2. These molecules are then used in the electron transport chain to generate ATP, the primary energy currency of cells.
3. What is the significance of pyruvate oxidation in aerobic respiration?
Ans. Pyruvate oxidation is a vital step in aerobic respiration, the process by which cells generate energy in the presence of oxygen. Without pyruvate oxidation, pyruvate would accumulate and glycolysis, the initial step of glucose breakdown, would halt. By converting pyruvate into acetyl-CoA, pyruvate oxidation allows for the efficient utilization of glucose and the subsequent production of ATP through the citric acid cycle and oxidative phosphorylation.
4. Are there any regulatory mechanisms that control pyruvate oxidation?
Ans. Yes, pyruvate oxidation is tightly regulated to ensure proper energy metabolism in cells. One of the main regulatory mechanisms involves the enzyme pyruvate dehydrogenase, which catalyzes the conversion of pyruvate to acetyl-CoA. Pyruvate dehydrogenase is regulated by various factors, including product inhibition, phosphorylation, and allosteric regulation. These mechanisms help control the flux of pyruvate and maintain metabolic balance.
5. Can pyruvate oxidation occur in the absence of oxygen?
Ans. No, pyruvate oxidation is an aerobic process that requires the presence of oxygen. In the absence of oxygen, pyruvate can be converted into other metabolites through fermentation pathways, such as lactic acid fermentation in muscle cells or ethanol fermentation in yeast. However, these pathways do not involve the complete oxidation of pyruvate and do not generate as much ATP as aerobic respiration.
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